Professional Summary
Education & Certifications
- Medical Education: Sidney Kimmel Medical College Thomas Jefferson University (1992) PA
- Fellowship: Yale University Pediatric Surgery (2001) CT
- Residency: Hospital of the University of Pennsylvania General Surgery Residency (1999) PA
- Residency: Children's Hospital of Philadelphia Pediatric Surgery Residency (1997) PA
- Internship: Hospital of the University of Pennsylvania General Surgery Residency (1993) PA
- Board Certification: American Board of Surgery, Pediatric Surgery (2002)
Administrative Appointments
- Associate Dean Maternal Child Health - Research, Stanford University School of Medicine (2016 - Present)
- Co-Director Stanford Metabolic Health Center, Stanford University School of Medicine (2017 - Present)
- Director Clinical Research Support Office, Stanford Children's Health (2018 - Present)
Publications
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Donor-derived, liver-specific protein expression after bone marrow transplantation
Jenkins, D. D., Streetz, K., Tataria, M., Sahar, D., Kurobe, M., Longaker, M. T., … Sylvester, K. G. (2004). Donor-derived, liver-specific protein expression after bone marrow transplantation. TRANSPLANTATION, 78(4), 530–36. -
Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells
Tataria, M., Quarto, N., Longaker, M. T., & Sylvester, K. G. (2006). Absence of the p53 tumor suppressor gene promotes osteogenesis in mesenchymal stem cells. JOURNAL OF PEDIATRIC SURGERY, 41(4), 624–32. -
Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation
Moss, R. L., Dimmitt, R. A., Barnhart, D. C., Sylvester, K. G., Brown, R. L., Powell, D. M., … Silverman, B. L. (2006). Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation. NEW ENGLAND JOURNAL OF MEDICINE, 354(21), 2225–34. -
Repair and regeneration: opportunities for carcinogenesis from tissue stem cells
Perryman, S. V., & Sylvester, K. G. (2006). Repair and regeneration: opportunities for carcinogenesis from tissue stem cells. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 10(2), 292–308. -
Stem cells: tissue regeneration and cancer.
Tataria, M., Perryman, S. V., & Sylvester, K. G. (2006). Stem cells: tissue regeneration and cancer. Seminars in Pediatric Surgery, 15(4), 284–92. -
Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells
Hu, M., Kurobe, M., Jeong, Y. J., Fuerer, C., Ghole, S., Nusse, R., & Sylvester, K. G. (2007). Wnt/beta-catenin signaling in murine hepatic transit amplifying progenitor cells. GASTROENTEROLOGY, 133(5), 1579–91. -
Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells
Streetz, K. L., Doyonnas, R., Grimm, D., Jenkins, D. D., Fuess, S., Perryman, S., … Kay, M. A. (2008). Hepatic parenchymal replacement in mice by transplanted allogeneic hepatocytes is facilitated by bone marrow transplantation and mediated by CD4 cells. HEPATOLOGY, 47(2), 706–18. -
Doxycycline sclerotherapy as primary treatment of head and neck lymphatic malformations in children
Nehra, D., Jacobson, L., Barnes, P., Mallory, B., Albanese, C. T., & Sylvester, K. G. (2008). Doxycycline sclerotherapy as primary treatment of head and neck lymphatic malformations in children. JOURNAL OF PEDIATRIC SURGERY, 43(3), 451–60. -
Hepatotoxin-Induced Changes in the Adult Murine Liver Promote MYC-Induced Tumorigenesis
Beer, S., Komatsubara, K., Bellovin, D. I., Kurobe, M., Sylvester, K., & Felsher, D. W. (2008). Hepatotoxin-Induced Changes in the Adult Murine Liver Promote MYC-Induced Tumorigenesis. PLOS ONE, 3(6). -
Clinical parameters do not adequately predict outcome in necrotizing enterocolitis: a multi-institutional study
Moss, R. L., Kalish, L. A., Duggan, C., Johnston, P., Brandt, M. L., Dunn, J. C. Y., … Sylvester, K. G. (2008). Clinical parameters do not adequately predict outcome in necrotizing enterocolitis: a multi-institutional study. JOURNAL OF PERINATOLOGY, 28(10), 665–674. -
Risk Factors for Intestinal Failure in Infants with Necrotizing Enterocolitis: A Glaser Pediatric Research Network Study
Duro, D., Kalish, L. A., Johnston, P., Jaksic, T., Mccarthy, M., Martin, C., … Duggan, C. (2010). Risk Factors for Intestinal Failure in Infants with Necrotizing Enterocolitis: A Glaser Pediatric Research Network Study. JOURNAL OF PEDIATRICS, 157(2), 203–U50. -
URINE PEPTIDOMICS FOR CLINICAL BIOMARKER DISCOVERY
Ling, X. B., Mellins, E. D., Sylvester, K. G., & Cohen, H. J. (2010). URINE PEPTIDOMICS FOR CLINICAL BIOMARKER DISCOVERY. ADVANCES IN CLINICAL CHEMISTRY, VOL 51, 51, 181–213. -
Risk Factors for Parenteral Nutrition-associated Liver Disease Following Surgical Therapy for Necrotizing Enterocolitis
Duro, D., Mitchell, P. D., Kalish, L. A., Martin, C., Mccarthy, M., Jaksic, T., … Duggan, C. (2011). Risk Factors for Parenteral Nutrition-associated Liver Disease Following Surgical Therapy for Necrotizing Enterocolitis. JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 52(5), 595–600. -
Wnt-beta-catenin Signaling Protects Against Hepatic Ischemia and Reperfusion Injury in Mice
Lehwald, N., Tao, G.-Z., Jang, K. Y., Sorkin, M., Knoefel, W. T., & Sylvester, K. G. (2011). Wnt-beta-catenin Signaling Protects Against Hepatic Ischemia and Reperfusion Injury in Mice. GASTROENTEROLOGY, 141(2), 707–U417. -
Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway
Viatour, P., Ehmer, U., Saddic, L. A., Dorrell, C., Andersen, J. B., Lin, C. W., … Sage, J. (2011). Notch signaling inhibits hepatocellular carcinoma following inactivation of the RB pathway. JOURNAL OF EXPERIMENTAL MEDICINE, 208(10), 1963–76. -
beta-Catenin Regulates Hepatic Mitochondrial Function and Energy Balance in Mice
Lehwald, N., Tao, G.-Z., Jang, K. Y., Papandreou, I., Liu, B., Liu, B., … Sylvester, K. G. (2012). beta-Catenin Regulates Hepatic Mitochondrial Function and Energy Balance in Mice. GASTROENTEROLOGY, 143(3), 754–64. -
SIRT1 and c-Myc Promote Liver Tumor Cell Survival and Predict Poor Survival of Human Hepatocellular Carcinomas
Jang, K. Y., Noh, S. J., Lehwald, N., Tao, G.-Z., Bellovin, D. I., Park, H. S., … Sylvester, K. G. (2012). SIRT1 and c-Myc Promote Liver Tumor Cell Survival and Predict Poor Survival of Human Hepatocellular Carcinomas. PLOS ONE, 7(9). -
The surgical management of necrotizing enterocolitis.
Kastenberg, Z. J., & Sylvester, K. G. (2013). The surgical management of necrotizing enterocolitis. Clinics in Perinatology, 40(1), 135–48. -
Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model.
Schulz, S., Wong, R. J., Jang, K. Y., Kalish, F., Chisholm, K. M., Zhao, H., … Stevenson, D. K. (2013). Heme oxygenase-1 deficiency promotes the development of necrotizing enterocolitis-like intestinal injury in a newborn mouse model. American Journal of Physiology. Gastrointestinal and Liver Physiology, 304(11), G991–G1001. -
Wnt/ß-Catenin Signaling Protects Mouse Liver against Oxidative Stress-induced Apoptosis through the Inhibition of Forkhead Transcription Factor FoxO3.
Tao, G.-Z., Lehwald, N., Jang, K. Y., Baek, J., Xu, B., Omary, M. B., & Sylvester, K. G. (2013). Wnt/ß-Catenin Signaling Protects Mouse Liver against Oxidative Stress-induced Apoptosis through the Inhibition of Forkhead Transcription Factor FoxO3. Journal of Biological Chemistry, 288(24), 17214–24. -
Bilateral cystic lung disease in a monoamnionic twin of an anencephalic: A case of glial heterotopia in the lungs.
Anderson, J. M., Adams, M. L., Morgan, T., Robinson, T., Enns, G. M., Keller, K. A., … Hintz, S. R. (2003). Bilateral cystic lung disease in a monoamnionic twin of an anencephalic: A case of glial heterotopia in the lungs. Presented at the Western Regional Meeting of the American-Federation-for-Medical-Research, CARMEL,CA,CA,CA: LIPPINCOTT WILLIAMS & WILKINS. -
In vivo selection of primary and bone-marrow-derived hepatocytes after allogeneic transplantation in mice
Streetz, K. L., Doyonnas, R., Jenkins, D., Perryman, S., Fuess, S., Lin, S., … Kay, M. A. (2006). In vivo selection of primary and bone-marrow-derived hepatocytes after allogeneic transplantation in mice. Presented at the 41st Annual Meeting of the European-Association-for-the-Study-of-the-Liver, VIENNA,AUSTRIA: ELSEVIER SCIENCE BV. -
ROLE OF IIEME OXYGENASE IN A MURINE MODEL OF EARLY NECROTIZING ENTEROCOLITIS
Schulz-Geske, S., Kalish, F. S., Jang, K. Y., Zhao, H., Huey, M., Vreman, H. J., … Stevenson, D. K. (2011). ROLE OF IIEME OXYGENASE IN A MURINE MODEL OF EARLY NECROTIZING ENTEROCOLITIS. JOURNAL OF INVESTIGATIVE MEDICINE, 59(1), 126–27. -
HEME OXYGENASE-1 DEFICIENCY PROMOTES NECROTIZING ENTEROCOLITIS DEVELOPMENT IN A MURINE MOUSE MODEL
Schulz, S., Jang, K., Kalish, F. S., Zhao, H., Vreman, H. J., Sylvester, K. S., … Stevenson, D. K. (2012). HEME OXYGENASE-1 DEFICIENCY PROMOTES NECROTIZING ENTEROCOLITIS DEVELOPMENT IN A MURINE MOUSE MODEL. JOURNAL OF INVESTIGATIVE MEDICINE, 60(1), 158–58. -
Evidence for canonical beta-catenin signaling in neuroblastomas
Ghole, S. A., Kuscuoglu, U., Hu, M., Jeong, Y. J., & Sylvester, K. G. (2007). Evidence for canonical beta-catenin signaling in neuroblastomas. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 205(3), S66–S66. -
WNT/B-CATENIN AND MITOCHONDRIAL FUNCTION IN RESPONSE TO METABOLIC STRESS AND ALD
Liu, B., Zhang, R., Tao, G., Lehwald, N. C., Liu, B., & Sylvester, K. G. (2013). WNT/B-CATENIN AND MITOCHONDRIAL FUNCTION IN RESPONSE TO METABOLIC STRESS AND ALD. Presented at the 36th Annual Scientific Meeting of the Research-Society-on-Alcoholism, ORLANDO,FL: WILEY-BLACKWELL. -
Hepatocyte targeting for quantifiable and functional cellular transplantation
Jenkins, D. D., Streetz, K., Kay, M., Longaker, M., & Sylvester, K. (2003). Hepatocyte targeting for quantifiable and functional cellular transplantation. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 197(3), S15–S15. -
Functional measurement of fusion in the liver after bone-marrow transplantation over time
Streetz, K. L., Jenkins, D., Longaker, G., Sylvester, K., & Kay, M. A. (2004). Functional measurement of fusion in the liver after bone-marrow transplantation over time. Presented at the 39th Annual Meeting of the European-Association-for-the-Study-of-the-Liver, BERLIN,GERMANY: ELSEVIER SCIENCE BV. -
Cell therapy for hepatocyte replacement through bone marrow derived myelomonocytic progenitors
Sylvester, K. G., Jenkins, D., Streetz, K., Doyannis, R., Perryman, S., Kay, M., & Blau, H. (2005). Cell therapy for hepatocyte replacement through bone marrow derived myelomonocytic progenitors. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 201(3), S47–S48. -
Multipotent progenitors from MSCs are regulated by Wnt/beta-catenin signaling
Tataria, M., Ailles, L., Jenkins, D., Longaker, M. T., Weissman, I., & Sylvester, K. (2005). Multipotent progenitors from MSCs are regulated by Wnt/beta-catenin signaling. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 201(3), S45–S45. -
The role of injury on the long-term expression of a hepatocyte transgene from bone marrow
Perryman, S. V., Jenkins, D., Streetz, K., Doyonnas, R., & Sylvester, K. (2005). The role of injury on the long-term expression of a hepatocyte transgene from bone marrow. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 201(3), S89–S89. -
Matched analysis of nonoperative management vs immediate appendectomy for perforated appendicitis
Henry, M. C. W., Gollin, G., Islam, S., Sylvester, K., Walker, A., Silverman, B. L., & Moss, R. L. (2007). Matched analysis of nonoperative management vs immediate appendectomy for perforated appendicitis. JOURNAL OF PEDIATRIC SURGERY, 42(1), 19–24. -
Intestinal involvement during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury in a mouse model
Sukhotnik, I., Kuscuoglu, U., Altindag, B., Tao, G.-Z., Lehwald, N., & Sylvester, K. G. (2011). Intestinal involvement during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury in a mouse model. JOURNAL OF PEDIATRIC SURGERY, 46(8), 1495–1502. -
Risk factors for the development of abdominal abscess following operation for perforated appendicitis in children - A multicenter case-control study
Henry, M. C. W., Walker, A., Silverman, B. L., Gollin, G., Islam, S., Sylvester, K., & Moss, R. L. (2007). Risk factors for the development of abdominal abscess following operation for perforated appendicitis in children - A multicenter case-control study. ARCHIVES OF SURGERY, 142(3), 236–241. -
A novel urine peptide biomarker-based algorithm for the prognosis of necrotising enterocolitis in human infants.
Sylvester, K. G., Ling, X. B., Liu, G. Y., Kastenberg, Z. J., Ji, J., Hu, Z., … Moss, R. L. (2014). A novel urine peptide biomarker-based algorithm for the prognosis of necrotising enterocolitis in human infants. Gut, 63(8), 1284–92. -
Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants.
Sylvester, K. G., Ling, X. B., Liu, G. Y. G., Kastenberg, Z. J., Ji, J., Hu, Z., … Moss, R. L. (2014). Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants. Journal of Pediatrics, 164(3), 607–12 e1 7. -
A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis.
Ji, J., Ling, X. B., Zhao, Y., Hu, Z., Zheng, X., Xu, Z., … Sylvester, K. G. (2014). A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis. PloS One, 9(2). -
Pilot Application of Magnetic Nanoparticle-Based Biosensor for Necrotizing Enterocolitis
Kim, D., Fu, C., Ling, X. B., Hu, Z., Tao, G., Zhao, Y., … Wang, S. X. (2014). Pilot Application of Magnetic Nanoparticle-Based Biosensor for Necrotizing Enterocolitis. Journal of Proteomics and Bioinformatics. -
Heterotaxy syndromes and abnormal bowel rotation.
Newman, B., Koppolu, R., Murphy, D., & Sylvester, K. (2014). Heterotaxy syndromes and abnormal bowel rotation. Pediatric Radiology, 44(5), 542–51. -
A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis.
Ji, J., Ling, X. B., Zhao, Y., Hu, Z., Zheng, X., Xu, Z., … Sylvester, K. G. (2014). A data-driven algorithm integrating clinical and laboratory features for the diagnosis and prognosis of necrotizing enterocolitis. PloS One, 9(2). -
Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants.
Sylvester, K. G., Ling, X. B., Liu, G. Y. G., Kastenberg, Z. J., Ji, J., Hu, Z., … Moss, R. L. (2014). Urine protein biomarkers for the diagnosis and prognosis of necrotizing enterocolitis in infants. Journal of Pediatrics, 164(3), 607–12 e7. -
Effect of deregionalized care on mortality in very low-birth-weight infants with necrotizing enterocolitis.
Kastenberg, Z. J., Lee, H. C., Profit, J., Gould, J. B., & Sylvester, K. G. (2015). Effect of deregionalized care on mortality in very low-birth-weight infants with necrotizing enterocolitis. JAMA Pediatrics, 169(1), 26–32. -
CK2 alpha phosphorylates DBC1 and is involved in the progression of gastric carcinoma and predicts poor survival of gastric carcinoma patients
Bae, J. S., Park, S.-H., Kim, K. M., Kwon, K. S., Kim, C. Y., Lee, H. K., … Jang, K. Y. (2015). CK2 alpha phosphorylates DBC1 and is involved in the progression of gastric carcinoma and predicts poor survival of gastric carcinoma patients. INTERNATIONAL JOURNAL OF CANCER, 136(4), 797–809. -
Risk prediction of emergency department revisit 30 days post discharge: a prospective study.
Hao, S., Jin, B., Shin, A. Y., Zhao, Y., Zhu, C., Li, Z., … Ling, X. B. (2014). Risk prediction of emergency department revisit 30 days post discharge: a prospective study. PloS One, 9(11). -
Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe.
Apfeld, J. C., Wren, S. M., Macheka, N., Mbuwayesango, B. A., Bruzoni, M., Sylvester, K. G., & Kastenberg, Z. J. (2015). Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe. Surgery, 158(6), 1475–80. -
Urine biomarkers for necrotizing enterocolitis
Sylvester, K. G., & Moss, R. L. (2015). Urine biomarkers for necrotizing enterocolitis. PEDIATRIC SURGERY INTERNATIONAL, 31(5), 421–29. -
A robust estimation model for surgery durations with temporal, operational, and surgery team effects
Kayis, E., Khaniyev, T. T., Suermondt, J., & Sylvester, K. (2015). A robust estimation model for surgery durations with temporal, operational, and surgery team effects. HEALTH CARE MANAGEMENT SCIENCE, 18(3), 222–33. -
Impaired Activity of Blood Coagulant Factor XIII in Patients with Necrotizing Enterocolitis
Tao, G.-Z., Liu, B., Zhang, R., Liu, G., Abdullah, F., Harris, M. C., … Sylvester, K. G. (2015). Impaired Activity of Blood Coagulant Factor XIII in Patients with Necrotizing Enterocolitis. SCIENTIFIC REPORTS, 5. -
Development, Validation and Deployment of a Real Time 30 Day Hospital Readmission Risk Assessment Tool in the Maine Healthcare Information Exchange.
Hao, S., Wang, Y., Jin, B., Shin, A. Y., Zhu, C., Huang, M., … Ling, X. B. (2015). Development, Validation and Deployment of a Real Time 30 Day Hospital Readmission Risk Assessment Tool in the Maine Healthcare Information Exchange. PloS One, 10(10). -
Online Prediction of Health Care Utilization in the Next Six Months Based on Electronic Health Record Information: A Cohort and Validation Study
Hu, Z., Hao, S., Jin, B., Shin, A. Y., Zhu, C., Huang, M., … Ling, X. (2015). Online Prediction of Health Care Utilization in the Next Six Months Based on Electronic Health Record Information: A Cohort and Validation Study. JOURNAL OF MEDICAL INTERNET RESEARCH, 17(9). -
NLP based congestive heart failure case finding: A prospective analysis on statewide electronic medical records.
Wang, Y., Luo, J., Hao, S., Xu, H., Shin, A. Y., Jin, B., … Ling, X. B. (2015). NLP based congestive heart failure case finding: A prospective analysis on statewide electronic medical records. International Journal of Medical Informatics, 84(12), 1039–47. -
Real-time web-based assessment of total population risk of future emergency department utilization: statewide prospective active case finding study.
Hu, Z., Jin, B., Shin, A. Y., Zhu, C., Zhao, Y., Hao, S., … Ling, X. B. (2015). Real-time web-based assessment of total population risk of future emergency department utilization: statewide prospective active case finding study. Interactive Journal of Medical Research, 4(1). -
Risk prediction of emergency department revisit 30 days post discharge: a prospective study.
Hao, S., Jin, B., Shin, A. Y., Zhao, Y., Zhu, C., Li, Z., … Ling, X. B. (2014). Risk prediction of emergency department revisit 30 days post discharge: a prospective study. PloS One, 9(11), e112944. -
Hippo/YAP, ß-catenin, and the cancer cell: a "ménage à trois" in hepatoblastoma.
Sylvester, K. G., & Colnot, S. (2014). Hippo/YAP, ß-catenin, and the cancer cell: a "ménage à trois" in hepatoblastoma. Gastroenterology, 147(3), 562–65. -
Impaired Activity of Blood Coagulant Factor XIII in Patients with Necrotizing Enterocolitis.
Tao, G.-Z., Liu, B., Zhang, R., Liu, G., Abdullah, F., Harris, M. C., … Sylvester, K. G. (2015). Impaired Activity of Blood Coagulant Factor XIII in Patients with Necrotizing Enterocolitis. Scientific Reports, 5, 13119-? -
Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe
Apfeld, J. C., Wren, S. M., Macheka, N., Mbuwayesango, B. A., Bruzoni, M., Sylvester, K. G., & Kastenberg, Z. J. (2015). Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe. SURGERY, 158(6), 1476–81. -
Augmented Wnt Signaling as a Therapeutic Tool to Prevent Ischemia/Reperfusion Injury in Liver: Preclinical Studies in a Mouse Model
Liu, B., Zhang, R., Tao, G., Lehwald, N. C., Liu, B., Koh, Y., & Sylvester, K. G. (2015). Augmented Wnt Signaling as a Therapeutic Tool to Prevent Ischemia/Reperfusion Injury in Liver: Preclinical Studies in a Mouse Model. LIVER TRANSPLANTATION, 21(12), 1533–42. -
Development, Validation and Deployment of a Real Time 30 Day Hospital Readmission Risk Assessment Tool in the Maine Healthcare Information Exchange
Hao, S., Wang, Y., Jin, B., Shin, A. Y., Zhu, C., Huang, M., … Ling, X. B. (2015). Development, Validation and Deployment of a Real Time 30 Day Hospital Readmission Risk Assessment Tool in the Maine Healthcare Information Exchange. PLOS ONE, 10(10). -
Prospective stratification of patients at risk for emergency department revisit: resource utilization and population management strategy implications.
Jin, B., Zhao, Y., Hao, S., Shin, A. Y., Wang, Y., Zhu, C., … Ling, X. B. (2016). Prospective stratification of patients at risk for emergency department revisit: resource utilization and population management strategy implications. BMC Emergency Medicine, 16(1), 10-? -
Augmented Wnt signaling as a therapeutic tool to prevent ischemia/reperfusion injury in liver: Preclinical studies in a mouse model.
Liu, B., Zhang, R., Tao, G., Lehwald, N. C., Liu, B., Koh, Y., & Sylvester, K. G. (2015). Augmented Wnt signaling as a therapeutic tool to prevent ischemia/reperfusion injury in liver: Preclinical studies in a mouse model. Liver Transplantation , 21(12), 1533–42. -
Improving prediction of surgery duration using operational and temporal factors.
Kayis, E., Wang, H., Patel, M., Gonzalez, T., Jain, S., Ramamurthi, R. J., … Sylvester, K. (2012). Improving prediction of surgery duration using operational and temporal factors. AMIA ... Annual Symposium Proceedings / AMIA Symposium. AMIA Symposium, 2012, 456–62. -
Serological Targeted Analysis of an ITIH4 Peptide Isoform: A Preterm Birth Biomarker and Its Associated SNP Implications
Tan, Z., Hu, Z., Cai, E. Y., Alev, C., Yang, T., Li, Z., … Ling, X. B. (2015). Serological Targeted Analysis of an ITIH4 Peptide Isoform: A Preterm Birth Biomarker and Its Associated SNP Implications. JOURNAL OF GENETICS AND GENOMICS, 42(9), 507–10. -
Pilot Application of Magnetic Nanoparticle-Based Biosensor for Necrotizing Enterocolitis.
Kim, D., Fu, C., Ling, X. B., Hu, Z., Tao, G., Zhao, Y., … Wang, S. X. (2015). Pilot Application of Magnetic Nanoparticle-Based Biosensor for Necrotizing Enterocolitis. Journal of Proteomics & Bioinformatics. -
Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy.
Fragiadakis, G. K., Baca, Q. J., Gherardini, P. F., Ganio, E. A., Gaudilliere, D. K., Tingle, M., … Gaudilliere, B. L. (2016). Mapping the Fetomaternal Peripheral Immune System at Term Pregnancy. Journal of Immunology . -
Web-based Real-Time Case Finding for the Population Health Management of Patients With Diabetes Mellitus: A Prospective Validation of the Natural Language Processing-Based Algorithm With Statewide Electronic Medical Records.
Zheng, L., Wang, Y., Hao, S., Shin, A. Y., Jin, B., Ngo, A. D., … Ling, X. B. (2016). Web-based Real-Time Case Finding for the Population Health Management of Patients With Diabetes Mellitus: A Prospective Validation of the Natural Language Processing-Based Algorithm With Statewide Electronic Medical Records. JMIR Medical Informatics, 4(4). -
Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness
Wang, Y., Li, Z., Hu, G., Hao, S., Deng, X., Huang, M., … Ling, X. B. (2016). Unique Molecular Patterns Uncovered in Kawasaki Disease Patients with Elevated Serum Gamma Glutamyl Transferase Levels: Implications for Intravenous Immunoglobulin Responsiveness. PLOS ONE, 11(12). -
Acylcarnitine Profiles Reflect Metabolic Vulnerability for Necrotizing Enterocolitis in Newborns Born Premature.
Sylvester, K. G., Kastenberg, Z. J., Moss, R. L., Enns, G. M., Cowan, T. M., Shaw, G. M., … Jelliffe-Pawlowski, L. L. (2017). Acylcarnitine Profiles Reflect Metabolic Vulnerability for Necrotizing Enterocolitis in Newborns Born Premature. Journal of Pediatrics, 181, 80–85 e1. -
CK2 alpha/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients
Bae, J. S., Park, S.-H., Jamiyandorj, U., Kim, K. M., Noh, S. J., Kim, J. R., … Jang, K. Y. (2016). CK2 alpha/CSNK2A1 Phosphorylates SIRT6 and Is Involved in the Progression of Breast Carcinoma and Predicts Shorter Survival of Diagnosed Patients. AMERICAN JOURNAL OF PATHOLOGY, 186(12), 3297–3315. -
Prediction of neonatal respiratory distress in pregnancies complicated by fetal lung masses.
Girsen, A. I., Hintz, S. R., Sammour, R., Naqvi, A., El-Sayed, Y. Y., Sherwin, K., … Blumenfeld, Y. J. (2017). Prediction of neonatal respiratory distress in pregnancies complicated by fetal lung masses. Prenatal Diagnosis. -
Advanced minimal access surgery in infants weighing less than 3kg: A single center experience.
Wall, J. K., Sinclair, T. J., Kethman, W., Williams, C., Albanese, C., Sylvester, K. G., & Bruzoni, M. (2017). Advanced minimal access surgery in infants weighing less than 3kg: A single center experience. Journal of Pediatric Surgery. -
Involvement of prolyl isomerase PIN1 in the cell cycle progression and proliferation of hepatic oval cells
Risal, P., Shrestha, N., Chand, L., Sylvester, K. G., & Jeong, Y. J. (2017). Involvement of prolyl isomerase PIN1 in the cell cycle progression and proliferation of hepatic oval cells. PATHOLOGY RESEARCH AND PRACTICE, 213(4), 373–80. -
Advanced minimal access surgery in infants weighing less than 3kg: A single center experience.
Wall, J. K., Sinclair, T. J., Kethman, W., Williams, C., Albanese, C., Sylvester, K. G., & Bruzoni, M. (2017). Advanced minimal access surgery in infants weighing less than 3kg: A single center experience. Journal of Pediatric Surgery. -
The Effect of Level of Care on Gastroschisis Outcomes.
Apfeld, J. C., Kastenberg, Z. J., Sylvester, K. G., & Lee, H. C. (2017). The Effect of Level of Care on Gastroschisis Outcomes. The Journal of Pediatrics, 190, 79–84.e1. -
Prediction of Incident Hypertension Within the Next Year: Prospective Study Using Statewide Electronic Health Records and Machine Learning.
Ye, C., Fu, T., Hao, S., Zhang, Y., Wang, O., Jin, B., … Ling, X. (2018). Prediction of Incident Hypertension Within the Next Year: Prospective Study Using Statewide Electronic Health Records and Machine Learning. Journal of Medical Internet Research, 20(1), e22. -
Point-of-Care Fecal Calprotectin Monitoring in Preterm Infants at Risk for Necrotizing Enterocolitis.
Nakayuenyongsuk, W., Christofferson, M., Stevenson, D. K., Sylvester, K., Lee, H. C., & Park, K. T. (2018). Point-of-Care Fecal Calprotectin Monitoring in Preterm Infants at Risk for Necrotizing Enterocolitis. The Journal of Pediatrics. -
CVR at the time of mid-trimester diagnosis of congenital lung lesions as a predictor of adverse neonatal outcomes
Sammour, R., Hintz, S., Davis, A., Riley, K., Barth, R., Rubesova, E., … Blumenfeld, Y. (2015). CVR at the time of mid-trimester diagnosis of congenital lung lesions as a predictor of adverse neonatal outcomes. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. MOSBY-ELSEVIER. -
Gene expression network analysis in aneuploid human trophoblast progenitor cells (TBPC) reveals modular structures
Leon-Martinez, D., Ling, X. B., Hao, S., Sylvester, K., & Bianco, K. (2018). Gene expression network analysis in aneuploid human trophoblast progenitor cells (TBPC) reveals modular structures. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 218(1), S163–S164. -
Development of the necrotizing enterocolitis society registry and biorepository
Ralls, M. W., Gadepalli, S. K., Sylvester, K. G., & Good, M. (2018). Development of the necrotizing enterocolitis society registry and biorepository. SEMINARS IN PEDIATRIC SURGERY, 27(1), 25–28. -
Changing the paradigm of defining, detecting, and diagnosing NEC: Perspectives on Bell's stages and biomarkers for NEC
Gephart, S. M., Gordon, P. V., Penn, A. H., Gregory, K. E., Swanson, J. R., Maheshwari, A., & Sylvester, K. (2018). Changing the paradigm of defining, detecting, and diagnosing NEC: Perspectives on Bell's stages and biomarkers for NEC. SEMINARS IN PEDIATRIC SURGERY, 27(1), 3–10. -
Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model
Kourula, S., Ang, J., Zhao, H., Kalish, F., Vandenabeele, P., Sylvester, K. G., … Stevenson, D. K. (2017). Heme Oxygenase Activity and Heme Binding in a Neonatal Mouse Model. NEONATOLOGY, 112(4), 376–83. -
A Multi-Omics Analysis of Human Nucleus-Coded Mitochondrial Genes with Mouse Extraembryonic Tissue/Placenta Phenotypes: Implications in Mitochondria-Mediated Maternal and Fetal Complications.
Hu, G., Chen, R., Deng, X., Li, Z., Mo, L., Hao, S., … Ling, X. B. (2016). A Multi-Omics Analysis of Human Nucleus-Coded Mitochondrial Genes with Mouse Extraembryonic Tissue/Placenta Phenotypes: Implications in Mitochondria-Mediated Maternal and Fetal Complications. REPRODUCTIVE SCIENCES, 23, 320A. -
Estimating One-Year Risk of Incident Chronic Kidney Disease: Retrospective Development and Validation Study Using Electronic Medical Record Data From the State of Maine.
Hao, S., Fu, T., Wu, Q., Jin, B., Zhu, C., Hu, Z., … Ling, X. B. (2017). Estimating One-Year Risk of Incident Chronic Kidney Disease: Retrospective Development and Validation Study Using Electronic Medical Record Data From the State of Maine. JMIR Medical Informatics, 5(3), e21. -
Defining and characterizing the critical transition state prior to the type 2 diabetes disease.
Jin, B., Liu, R., Hao, S., Li, Z., Zhu, C., Zhou, X., … Ling, X. B. (2017). Defining and characterizing the critical transition state prior to the type 2 diabetes disease. PloS One, 12(7), e0180937. -
Assessing Statewide All-Cause Future One-Year Mortality: Prospective Study With Implications for Quality of Life, Resource Utilization, and Medical Futility.
Guo, Y., Zheng, G., Fu, T., Hao, S., Ye, C., Zheng, L., … Ling, X. B. (2018). Assessing Statewide All-Cause Future One-Year Mortality: Prospective Study With Implications for Quality of Life, Resource Utilization, and Medical Futility. Journal of Medical Internet Research, 20(6), e10311. -
Identification of independent metabolic risk groups for necrotizing enterocolitis through machine learning
Oltman, S. P., Rogers, E. E., Pantell, M., Baer, R. J., Rand, L., Ryckman, K. K., … Jeliffe-Pawlowski, L. (2017). Identification of independent metabolic risk groups for necrotizing enterocolitis through machine learning. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 216(1), S372. -
FAM83H is involved in the progression of hepatocellular carcinoma and is regulated by MYC
Kim, K. M., Park, S.-H., Bae, J. S., Noh, S. J., Tao, G.-Z., Kim, J. R., … Jang, K. Y. (2017). FAM83H is involved in the progression of hepatocellular carcinoma and is regulated by MYC. SCIENTIFIC REPORTS, 7. -
Obstetric and neonatal outcomes in pregnancies complicated by fetal lung masses: does final histology matter?
Anderson, J. N., Girsen, A. I., Hintz, S. R., El-Sayed, Y. Y., Davis, A. S., Barth, R. A., … Blumenfeld, Y. J. (2019). Obstetric and neonatal outcomes in pregnancies complicated by fetal lung masses: does final histology matter? AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. MOSBY-ELSEVIER. -
Congenital diaphragmatic hernia-associated neonatal morbidity and mortality based on TOTAL trial severity designation
Boissiere, J. C., Anderson, J. N., Girsen, A. I., Hintz, S. R., El-Sayed, Y. Y., Van Meurs, K. P., … Blumenfeld, Y. J. (2019). Congenital diaphragmatic hernia-associated neonatal morbidity and mortality based on TOTAL trial severity designation. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. MOSBY-ELSEVIER. -
Predicting Pathology From Imaging in Children Undergoing Resection of Congenital Lung Lesions.
Narayan, R. R., Abadilla, N., Greenberg, D. R., Sylvester, K. G., Hintz, S. R., Barth, R. A., & Bruzoni, M. (2018). Predicting Pathology From Imaging in Children Undergoing Resection of Congenital Lung Lesions. The Journal of Surgical Research, 236, 68–73. -
Biomarker Discovery and Utility in Necrotizing Enterocolitis.
Goldstein, G. P., & Sylvester, K. G. (2019). Biomarker Discovery and Utility in Necrotizing Enterocolitis. Clinics in Perinatology, 46(1), 1–17. -
The role of Wnt signaling in maintaining the neuroblast phenotype in neuroblastomas
Ghole, S. A., Kuscuoglu, U., & Sylvester, K. (2008). The role of Wnt signaling in maintaining the neuroblast phenotype in neuroblastomas. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 207(3), S53. -
Role of the Wnt/beta-Catenin Pathway in the Pathogenesis of Alcoholic Liver Disease
Behari, J., & Sylvester, K. G. (2017). Role of the Wnt/beta-Catenin Pathway in the Pathogenesis of Alcoholic Liver Disease. CURRENT MOLECULAR PHARMACOLOGY, 10(3), 186–94. -
Necroptosis is Associated with Development Dependent Enterocyte Death in a Mouse Model of Intestinal Injury and Human Necrotizing Enterocolitis
Sinclair, T., Tao, G., Liu, B., Zhang, R., Lu, C.-T., & Sylvester, K. G. (2016). Necroptosis is Associated with Development Dependent Enterocyte Death in a Mouse Model of Intestinal Injury and Human Necrotizing Enterocolitis. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. ELSEVIER SCIENCE INC. -
Advanced Minimal Access Surgery in Infants Weighing Less Than 3 Kilograms: A Single Center Experience
Sinclair, T., Wall, J. K., Albanese, C., Sylvester, K. G., & Bruzoni, M. (2016). Advanced Minimal Access Surgery in Infants Weighing Less Than 3 Kilograms: A Single Center Experience. JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. ELSEVIER SCIENCE INC. -
Risk Prediction of Stroke: A Prospective Statewide Study on Patients in Maine
Zheng, L., Wang, V., Hao, S., Sylvester, K. G., Ling, X. B., Jin, B., … Rogow, T. (2015). Risk Prediction of Stroke: A Prospective Statewide Study on Patients in Maine. PROCEEDINGS 2015 IEEE INTERNATIONAL CONFERENCE ON BIOINFORMATICS AND BIOMEDICINE, 853–55. -
Recent Advances in Prevention and Therapies for Clinical or Experimental Necrotizing Enterocolitis.
Wang, K., Tao, G., & Sylvester, K. G. (2019). Recent Advances in Prevention and Therapies for Clinical or Experimental Necrotizing Enterocolitis. Digestive Diseases and Sciences. -
FAM83H is involved in the progression of hepatocellular carcinoma and is regulated by MYC.
Kim, K. M., Park, S.-H. H., Bae, J. S., Noh, S. J., Tao, G.-Z. Z., Kim, J. R., … Jang, K. Y. (2017). FAM83H is involved in the progression of hepatocellular carcinoma and is regulated by MYC. Scientific Reports, 7(1), 3274. -
The disproportionate cost of operation and congenital anomalies ininfancy.
Apfeld, J. C., Kastenberg, Z. J., Gibbons, A. T., Phibbs, C. S., Lee, H. C., & Sylvester, K. G. (2019). The disproportionate cost of operation and congenital anomalies ininfancy. Surgery. -
Point-of-Care Fecal Calprotectin Monitoring in Preterm Infants at Risk for Necrotizing Enterocolitis
Nakayuenyongsuk, W., Christofferson, M., Stevenson, D. K., Sylvester, K., Lee, H. C., & Park, K. T. (2018). Point-of-Care Fecal Calprotectin Monitoring in Preterm Infants at Risk for Necrotizing Enterocolitis. JOURNAL OF PEDIATRICS, 196, 98-+. -
Prediction of the 1-Year Risk of Incident Lung Cancer: Prospective Study Using Electronic Health Records from the State of Maine.
Wang, X., Zhang, Y., Hao, S., Zheng, L., Liao, J., Ye, C., … Ling, X. B. (2019). Prediction of the 1-Year Risk of Incident Lung Cancer: Prospective Study Using Electronic Health Records from the State of Maine. Journal of Medical Internet Research, 21(5), e13260. -
Recent Potential Noninvasive Biomarkers in Necrotizing Enterocolitis
Wang, K., Tao, G., Sun, Z., & Sylvester, K. G. (2019). Recent Potential Noninvasive Biomarkers in Necrotizing Enterocolitis. GASTROENTEROLOGY RESEARCH AND PRACTICE. -
Prediction of the 1-Year Risk of Incident Lung Cancer: Prospective Study Using Electronic Health Records from the State of Maine
Wang, X., Zhang, Y., Hao, S., Zheng, L., Liao, J., Ye, C., … Ling, X. B. (2019). Prediction of the 1-Year Risk of Incident Lung Cancer: Prospective Study Using Electronic Health Records from the State of Maine. JOURNAL OF MEDICAL INTERNET RESEARCH, 21(5). -
Biomarker Discovery and Utility in Necrotizing Enterocolitis
Goldstein, G. P., & Sylvester, K. G. (2019). Biomarker Discovery and Utility in Necrotizing Enterocolitis. CLINICS IN PERINATOLOGY, 46(1), 1-+. -
Predicting Pathology From Imaging in Children Undergoing Resection of Congenital Lung Lesions
Narayan, R. R., Abadilla, N., Greenberg, D. R., Sylvester, K. G., Hintz, S. R., Barth, R. A., & Bruzoni, M. (2019). Predicting Pathology From Imaging in Children Undergoing Resection of Congenital Lung Lesions. JOURNAL OF SURGICAL RESEARCH. ACADEMIC PRESS INC ELSEVIER SCIENCE. -
Recent Potential Noninvasive Biomarkers in Necrotizing Enterocolitis.
Wang, K., Tao, G., Sun, Z., & Sylvester, K. G. (2019). Recent Potential Noninvasive Biomarkers in Necrotizing Enterocolitis. Gastroenterology Research and Practice, 2019, 8413698. -
Donor-derived circulating cell-free DNA (ccfDNA) reference materials for concordance studies
Konigshofer, Y., Butler, M. G., Dickens, J., Bianco, K., Sylvester, K. G., Anekella, B., & Garlick, R. K. (2018). Donor-derived circulating cell-free DNA (ccfDNA) reference materials for concordance studies. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Prenatally diagnosed omphalocele: characteristics associated with adverse neonatal outcomes.
Chock, V. Y., Davis, A. S., Cho, S.-H., Bax, C., Fluharty, E., Weigel, N., … Hintz, S. R. (2019). Prenatally diagnosed omphalocele: characteristics associated with adverse neonatal outcomes. Journal of Perinatology : Official Journal of the California Perinatal Association. -
A Real-Time Early Warning System for Monitoring Inpatient Mortality Risk: Prospective Study Using Electronic Medical Record Data.
Ye, C., Wang, O., Liu, M., Zheng, L., Xia, M., Hao, S., … Ling, X. (2019). A Real-Time Early Warning System for Monitoring Inpatient Mortality Risk: Prospective Study Using Electronic Medical Record Data. Journal of Medical Internet Research, 21(7), e13719. -
Effects of gestational age at delivery and type of labor on neonatal outcomes among infants with gastroschisis.
Girsen, A. I., Davis, A. S., Hintz, S. R., Fluharty, E., Sherwin, K., Trepman, P., … Blumenfeld, Y. J. (2019). Effects of gestational age at delivery and type of labor on neonatal outcomes among infants with gastroschisis. The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 1–191. -
A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage.
Zheng, L., Zhang, Y., Hao, S., Chen, L., Sun, Z., Yan, C., … Ling, X. B. (2019). A proteomic clock for malignant gliomas: The role of the environment in tumorigenesis at the presymptomatic stage. PloS One, 14(10), e0223558. -
The disproportionate cost of operation and congenital anomalies in infancy
Apfeld, J. C., Kastenberg, Z. J., Gibbons, A. T., Phibbs, C. S., Lee, H. C., & Sylvester, K. G. (2019). The disproportionate cost of operation and congenital anomalies in infancy. SURGERY. MOSBY-ELSEVIER. -
Obstetric and neonatal outcomes in pregnancies complicated by fetal lung masses: does final histology matter?
Anderson, J. N., Girsen, A. I., Hintz, S. R., El-Sayed, Y. Y., Davis, A. S., Barth, R. A., … Blumenfeld, Y. J. (2019). Obstetric and neonatal outcomes in pregnancies complicated by fetal lung masses: does final histology matter? The Journal of Maternal-Fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 1–7. -
In fetuses with congenital lung masses, decreased ventricular and atrioventricular valve dimensions are associated with lesion size and clinical outcome.
Mardy, C., Blumenfeld, Y. J., Arunamata, A. A., Girsen, A. I., Sylvester, K. G., Halabi, S., … Maskatia, S. A. (2019). In fetuses with congenital lung masses, decreased ventricular and atrioventricular valve dimensions are associated with lesion size and clinical outcome. Prenatal Diagnosis. -
Recent Advances in Prevention and Therapies for Clinical or Experimental Necrotizing Enterocolitis
Wang, K., Tao, G., & Sylvester, K. G. (2019). Recent Advances in Prevention and Therapies for Clinical or Experimental Necrotizing Enterocolitis. DIGESTIVE DISEASES AND SCIENCES, 64(11), 3078–85. -
Survival of infants with congenital diaphragmatic hernia in California: impact of hospital, clinical, and sociodemographic factors.
Carmichael, S. L., Ma, C., Lee, H. C., Shaw, G. M., Sylvester, K. G., & Hintz, S. R. (2020). Survival of infants with congenital diaphragmatic hernia in California: impact of hospital, clinical, and sociodemographic factors. Journal of Perinatology : Official Journal of the California Perinatal Association. -
Development of an early-warning system for high-risk patients for suicide attempt using deep learning and electronic health records.
Zheng, L., Wang, O., Hao, S., Ye, C., Liu, M., Xia, M., … Ling, X. B. (2020). Development of an early-warning system for high-risk patients for suicide attempt using deep learning and electronic health records. Translational Psychiatry, 10(1), 72. -
Changes in pregnancy-related serum biomarkers early in gestation are associated with later development of preeclampsia.
Hao, S., You, J., Chen, L., Zhao, H., Huang, Y., Zheng, L., … Ling, X. B. (2020). Changes in pregnancy-related serum biomarkers early in gestation are associated with later development of preeclampsia. PloS One, 15(3), e0230000. -
Identification of elders at higher risk for fall with statewide electronic health records and a machine learning algorithm.
Ye, C., Li, J., Hao, S., Liu, M., Jin, H., Zheng, L., … Ling, X. B. (2020). Identification of elders at higher risk for fall with statewide electronic health records and a machine learning algorithm. International Journal of Medical Informatics, 137, 104105. -
Progressive Metabolic Dysfunction and Nutritional Variability Precedes Necrotizing Enterocolitis.
Sinclair, T. J., Ye, C., Chen, Y., Zhang, D., Li, T., Ling, X. B., … Sylvester, K. G. (2020). Progressive Metabolic Dysfunction and Nutritional Variability Precedes Necrotizing Enterocolitis. Nutrients, 12(5). -
Treating Center Volume and Congenital Diaphragmatic Hernia Outcomes in California.
Apfeld, J. C., Kastenberg, Z. J., Gibbons, A. T., Carmichael, S. L., Lee, H. C., & Sylvester, K. G. (2020). Treating Center Volume and Congenital Diaphragmatic Hernia Outcomes in California. The Journal of Pediatrics. -
Towards personalized medicine in maternal and child health: integrating biologic and social determinants.
Stevenson, D. K., Wong, R. J., Aghaeepour, N., Maric, I., Angst, M. S., Contrepois, K., … Katz, M. (2020). Towards personalized medicine in maternal and child health: integrating biologic and social determinants. Pediatric Research. -
Expression of antibody-drug conjugates (ADC) biomarkers in colorectal cancer.
Thyparambil, S. P., Liao, W.-L., An, E., Tian, Y., Heaton, R., Sylvester, K. G., & Ling, X. B. (2020). Expression of antibody-drug conjugates (ADC) biomarkers in colorectal cancer. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Racial/ethnic disparities and human milk use in necrotizing enterocolitis.
Goldstein, G. P., Pai, V. V., Liu, J., Sigurdson, K., Vernon, L. B., Lee, H. C., … Profit, J. (2020). Racial/ethnic disparities and human milk use in necrotizing enterocolitis. Pediatric Research, 88(Suppl 1), 3–9. -
High-throughput quantitation of serological ceramides/dihydroceramides by LC/MS/MS: Pregnancy baseline biomarkers and potential metabolic messengers.
Huang, Q., Hao, S., Yao, X., You, J., Li, X., Lai, D., … Ling, X. B. (2020). High-throughput quantitation of serological ceramides/dihydroceramides by LC/MS/MS: Pregnancy baseline biomarkers and potential metabolic messengers. Journal of Pharmaceutical and Biomedical Analysis, 192, 113639. -
Proteomic profiling to identify therapeutics targets in glioblastoma (GBM).
Thyparambil, S. P., Liao, W.-L., An, E., Bhalkikar, A., Heaton, R., Sylvester, K. G., & Ling, X. B. (2020). Proteomic profiling to identify therapeutics targets in glioblastoma (GBM). JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Kinetics of SARS-CoV-2 positivity of infected and recovered patients from a single center.
Huang, J., Zheng, L., Li, Z., Hao, S., Ye, F., Chen, J., … Ling, X. B. (2020). Kinetics of SARS-CoV-2 positivity of infected and recovered patients from a single center. Scientific Reports, 10(1), 18629. -
Maternal metabolic profiling to assess fetal gestational age and predict preterm delivery: a two-centre retrospective cohort study in the US.
Sylvester, K. G., Hao, S., You, J., Zheng, L., Tian, L., Yao, X., … Ling, X. B. (2020). Maternal metabolic profiling to assess fetal gestational age and predict preterm delivery: a two-centre retrospective cohort study in the US. BMJ Open, 10(12), e040647. -
Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States.
Casaburi, G., Duar, R. M., Brown, H., Mitchell, R. D., Kazi, S., Chew, S., … Freeman, S. L. (2021). Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States. Scientific Reports, 11(1), 1472. -
Electronic Health Record-Based Prediction of 1-Year Risk of Incident Cardiac Dysrhythmia: Prospective Case-Finding Algorithm Development and Validation Study.
Zhang, Y., Han, Y., Gao, P., Mo, Y., Hao, S., Huang, J., … Ling, X. (2021). Electronic Health Record-Based Prediction of 1-Year Risk of Incident Cardiac Dysrhythmia: Prospective Case-Finding Algorithm Development and Validation Study. JMIR Medical Informatics, 9(2), e23606. -
Deviation from the precisely timed phenomic ageotypes can assist in early CRC screening and reveal underlying pathophysiology.
Thyparambil, S. P., You, J., Liu, K., Sun, H., Peng, J., Cai, S., … Ling, X. B. (2020). Deviation from the precisely timed phenomic ageotypes can assist in early CRC screening and reveal underlying pathophysiology. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Understanding how biologic and social determinants affect disparities in preterm birth and outcomes of preterm infants in the NICU.
Stevenson, D. K., Aghaeepour, N., Maric, I., Angst, M. S., Darmstadt, G. L., Druzin, M. L., … Wong, R. J. (2021). Understanding how biologic and social determinants affect disparities in preterm birth and outcomes of preterm infants in the NICU. Seminars in Perinatology, 151408. -
Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset.
Stelzer, I. A., Ghaemi, M. S., Han, X., Ando, K., Hedou, J. J., Feyaerts, D., … Gaudilliere, B. (2021). Integrated trajectories of the maternal metabolome, proteome, and immunome predict labor onset. Science Translational Medicine, 13(592). -
Author Correction: Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States.
Casaburi, G., Duar, R. M., Brown, H., Mitchell, R. D., Kazi, S., Chew, S., … Freeman, S. L. (2021). Author Correction: Metagenomic insights of the infant microbiome community structure and function across multiple sites in the United States. Scientific Reports, 11(1), 11050. -
Novel Approaches to Develop Critical Reference Materials for Noninvasive Prenatal Testing: A Pilot Study.
Bianco, K., Sherwin, E. B., Konigshofer, Y., Girsen, A. I., Sylvester, K. G., & Garlick, R. K. (2021). Novel Approaches to Develop Critical Reference Materials for Noninvasive Prenatal Testing: A Pilot Study. The Journal of Applied Laboratory Medicine. -
Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial.
Blakely, M. L., Tyson, J. E., Lally, K. P., Hintz, S. R., Eggleston, B., Stevenson, D. K., … Higgins, R. D. (2021). Initial Laparotomy Versus Peritoneal Drainage in Extremely Low Birthweight Infants With Surgical Necrotizing Enterocolitis or Isolated Intestinal Perforation: A Multicenter Randomized Clinical Trial. Annals of Surgery, 274(4), e370–e380. -
Newborn screen metabolic panels reflect the impact of common disorders of pregnancy.
Reiss, J. D., Chang, A. L., Mayo, J. A., Bianco, K., Lee, H. C., Stevenson, D. K., … Sylvester, K. G. (2021). Newborn screen metabolic panels reflect the impact of common disorders of pregnancy. Pediatric Research. -
Multi-omics longitudinal analyses in stages I to III CRC patients: Surveillance liquid biopsy test to predict early recurrence and enable risk-stratified postoperative CRC management.
Liu, X., Zhang, Y., Zhu, X., Thyparambil, S. P., Liao, W.-L., Zheng, X.-B., … Wu, X. (2021). Multi-omics longitudinal analyses in stages I to III CRC patients: Surveillance liquid biopsy test to predict early recurrence and enable risk-stratified postoperative CRC management. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation.
Huang, Q., Hao, S., You, J., Yao, X., Li, Z., Schilling, J., … Ling, X. B. (2021). Early-pregnancy prediction of risk for pre-eclampsia using maternal blood leptin/ceramide ratio: discovery and confirmation. BMJ Open, 11(11), e050963. -
Identification of patients at risk of new onset heart failure: Utilizing a large statewide health information exchange to train and validate a risk prediction model.
Duong, S. Q., Zheng, L., Xia, M., Jin, B., Liu, M., Li, Z., … Ling, X. B. (2021). Identification of patients at risk of new onset heart failure: Utilizing a large statewide health information exchange to train and validate a risk prediction model. PloS One, 16(12), e0260885. -
Metabolic profiling of placental tissue and maternal plasma to identify biomarkers of placenta accreta spectrum
Miller, S. E., Contrepois, K., Michael, B., Cruz, G., Simms, I., Datoc, I., … Lyell, D. J. (2022). Metabolic profiling of placental tissue and maternal plasma to identify biomarkers of placenta accreta spectrum. AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY. MOSBY-ELSEVIER. -
Perinatal infection, inflammation, preterm birth, and brain injury: A review with proposals for future investigations.
Reiss, J. D., Peterson, L. S., Nesamoney, S. N., Chang, A. L., Pasca, A. M., Maric, I., … Stevenson, D. K. (2022). Perinatal infection, inflammation, preterm birth, and brain injury: A review with proposals for future investigations. Experimental Neurology, 113988. -
A data-driven health index for neonatal morbidities.
De Francesco, D., Blumenfeld, Y. J., Maric, I., Mayo, J. A., Chang, A. L., Fallahzadeh, R., … Aghaeepour, N. (2022). A data-driven health index for neonatal morbidities. IScience, 25(4), 104143. -
Deviation from the precisely timed age-associated patterns revealed by blood metabolomics to find CRC patients at risk of relapse at the CRC diagnosis
Thyparambil, S. P., Zhu, X., Zhang, Y., Sun, H., Peng, J., Cai, S., … Ling, X. (2022). Deviation from the precisely timed age-associated patterns revealed by blood metabolomics to find CRC patients at risk of relapse at the CRC diagnosis. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Serological Phenotyping Analysis Uncovers a Unique Metabolomic Pattern Associated With Early Onset of Type 2 Diabetes Mellitus.
Zhu, L., Huang, Q., Li, X., Jin, B., Ding, Y., Chou, C. J., … Ling, X. B. (2022). Serological Phenotyping Analysis Uncovers a Unique Metabolomic Pattern Associated With Early Onset of Type 2 Diabetes Mellitus. Frontiers in Molecular Biosciences, 9, 841209. -
Virtual reality experience for in utero fetal surgery: a new era of patient counselling and medical education
Blumenfeld, Y. J., Axelrod, D. M., Sarno, D., Hintz, S. R., Sylvester, K. G., Grant, G. A., … El-Sayed, Y. Y. (2022). Virtual reality experience for in utero fetal surgery: a new era of patient counselling and medical education. BMJ INNOVATIONS, 8(2), 95–97. -
Progressive Metabolic Abnormalities Associated with the Development of Neonatal Bronchopulmonary Dysplasia.
Ye, C., Wu, J., Reiss, J. D., Sinclair, T. J., Stevenson, D. K., Shaw, G. M., … Sylvester, K. G. (2022). Progressive Metabolic Abnormalities Associated with the Development of Neonatal Bronchopulmonary Dysplasia. Nutrients, 14(17). -
Metabolic model of necrotizing enterocolitis in the premature newborn gut resulting from enteric dysbiosis.
Casaburi, G., Wei, J., Kazi, S., Liu, J., Wang, K., Tao, G.-Z., … Sylvester, K. G. (2022). Metabolic model of necrotizing enterocolitis in the premature newborn gut resulting from enteric dysbiosis. Frontiers in Pediatrics, 10, 893059. -
Soluble Protein Hydrolysate Ameliorates Gastrointestinal Inflammation and Injury in 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis in Mice.
Wei, J., Tao, G., Xu, B., Wang, K., Liu, J., Chen, C.-H., … Sylvester, K. G. (2022). Soluble Protein Hydrolysate Ameliorates Gastrointestinal Inflammation and Injury in 2,4,6-Trinitrobenzene Sulfonic Acid-Induced Colitis in Mice. Biomolecules, 12(9). -
Butyrate induces development-dependent necrotizing enterocolitis-like intestinal epithelial injury via necroptosis.
Wang, K., Tao, G.-Z., Salimi-Jazi, F., Lin, P.-Y., Sun, Z., Liu, B., … Sylvester, K. G. (2022). Butyrate induces development-dependent necrotizing enterocolitis-like intestinal epithelial injury via necroptosis. Pediatric Research. -
Single center blind testing of a US multi-center validated diagnostic algorithm for Kawasaki disease in Taiwan.
Kuo, H.-C. C., Hao, S., Jin, B., Chou, C. J., Han, Z., Chang, L.-S. S., … Ling, X. B. (2022). Single center blind testing of a US multi-center validated diagnostic algorithm for Kawasaki disease in Taiwan. Frontiers in Immunology, 13, 1031387. -
Early prediction and longitudinal modeling of preeclampsia from multiomics.
Maric, I., Contrepois, K., Moufarrej, M. N., Stelzer, I. A., Feyaerts, D., Han, X., … Aghaeepour, N. (2022). Early prediction and longitudinal modeling of preeclampsia from multiomics. Patterns (New York, N.Y.), 3(12), 100655. -
Data-driven longitudinal characterization of neonatal health and morbidity.
De Francesco, D., Reiss, J. D., Roger, J., Tang, A. S., Chang, A. L., Becker, M., … Aghaeepour, N. (2023). Data-driven longitudinal characterization of neonatal health and morbidity. Science Translational Medicine, 15(683), eadc9854. -
Fecal Keratin 8 Is a Noninvasive and Specific Marker for Intestinal Injury in Necrotizing Enterocolitis.
Wang, K., Tao, G., Sun, Z., Wei, J., Liu, J., Taylor, J., … Sylvester, K. G. (2023). Fecal Keratin 8 Is a Noninvasive and Specific Marker for Intestinal Injury in Necrotizing Enterocolitis. Journal of Immunology Research, 2023, 5356646. -
Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy.
Zhang, Y., Sylvester, K. G., Jin, B., Wong, R. J., Schilling, J., Chou, C. J., … Ling, X. B. (2023). Development of a Urine Metabolomics Biomarker-Based Prediction Model for Preeclampsia during Early Pregnancy. Metabolites, 13(6). -
Altered expression of the L-arginine/nitric oxide pathway in ovarian cancer: metabolic biomarkers and biological implications.
Chen, L., Tang, Q., Zhang, K., Huang, Q., Ding, Y., Jin, B., … Ling, X. B. (2023). Altered expression of the L-arginine/nitric oxide pathway in ovarian cancer: metabolic biomarkers and biological implications. BMC Cancer, 23(1), 844.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
Practice Locations
LPCH- General Surgery Palo Alto, CA
Palo Alto, CAImportant Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Referring Physicians
PHYSICIAN HELPLINE
Fax: 650-320-9443
Monday–Friday, 8 a.m.–5 p.m.
Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
- Send referrals online
- Place radiology and lab orders
- View referral status
- Access medical records