

Professional Summary
Education & Certifications
- Residency: Johns Hopkins University School of Medicine (1992) MD
- Internship: Johns Hopkins University School of Medicine (1990) MD
- Medical Education: Johns Hopkins University School of Medicine (1989) MD
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- Board Certification: American Board of Internal Medicine, Medical Oncology (1995)
- Fellowship: Dana Farber Cancer Institute Hematology Oncology Fellowship (1995) MA
- B. A., Columbia, Chemistry (1985)
- M.D., Johns Hopkins, Medicine (1989)
Publications
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An initial experience using concurrent paclitaxel and radiation in the treatment of head and neck malignancies
Tishler, R. B., Busse, P. M., Norris, C. M., Rossi, R., Poulin, M., Thornhill, L., … Posner, M. R. (1999). An initial experience using concurrent paclitaxel and radiation in the treatment of head and neck malignancies. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 43(5), 1001–1008. -
The Prognostic Value of Thymidylate Synthase and p53 Expression in Patients Treated with Induction Chemotherapy for Squamous Cell Carcinoma of the Head and Neck.
Posner, Johnston, Tishler, ANDERSEN, Fiorentino, Busse, … NORRIS. (1998). The Prognostic Value of Thymidylate Synthase and p53 Expression in Patients Treated with Induction Chemotherapy for Squamous Cell Carcinoma of the Head and Neck. Oncologist, 3(6), 424–431. -
Re: "Sialadenosis: a presenting sign in Bulemia" (Head and Neck 20: 758-762, 1998)
Colevas, A. D. (1999). Re: "Sialadenosis: a presenting sign in Bulemia" (Head and Neck 20: 758-762, 1998). Head & Neck, 21(6), 582-? -
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Phase II trial of docetaxel, cisplatin, fluorouracil, and leucovorin as induction for squamous cell carcinoma of the head and neck
Colevas, A. D., Norris, C. M., Tishler, R. B., Fried, M. P., Gomolin, H. I., Amrein, P., … Posner, M. R. (1999). Phase II trial of docetaxel, cisplatin, fluorouracil, and leucovorin as induction for squamous cell carcinoma of the head and neck. JOURNAL OF CLINICAL ONCOLOGY, 17(11), 3503–3511. -
A phase II trial of palliative docetaxel plus 5-fluorouracil for squamous-cell cancer of the head and neck
Colevas, A. D., Adak, S., Amrein, P. C., Barton, J. J., Costello, R., & Posner, M. R. (2000). A phase II trial of palliative docetaxel plus 5-fluorouracil for squamous-cell cancer of the head and neck. ANNALS OF ONCOLOGY, 11(5), 535–539. -
The role of induction chemotherapy in the curative treatment of squamous cell cancer of the head and neck
Posner, M. R., Colevas, A. D., & Tishler, R. B. (2000). The role of induction chemotherapy in the curative treatment of squamous cell cancer of the head and neck. SEMINARS IN ONCOLOGY, 27(4), 13–24. -
Multicenter phase I-II trial of docetaxel, cisplatin, and fluorouracil induction chemotherapy for patients with locally advanced squamous cell cancer of the head and neck
Posner, M. R., Glisson, B., Frenette, G., al-Sarraf, M., Colevas, A. D., Norris, C. M., … Garay, C. A. (2001). Multicenter phase I-II trial of docetaxel, cisplatin, and fluorouracil induction chemotherapy for patients with locally advanced squamous cell cancer of the head and neck. JOURNAL OF CLINICAL ONCOLOGY, 19(4), 1096–1104. -
NCCN Practice Guidelines for head and neck cancers
Forastiere, A. A., Pfister, D. G., Ang, K., Brockstein, B., Colevas, A. D., Ellenhorn, J., … Wolf, G. T. (2000). NCCN Practice Guidelines for head and neck cancers. ONCOLOGY-NEW YORK, 14(11A), 163–194. -
A Phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck
Colevas, A. D., Amrein, P. C., Gomolin, H., Barton, J. J., Read, R. R., Adak, S., … Posner, M. R. (2001). A Phase II study of combined oral uracil and ftorafur with leucovorin for patients with squamous cell carcinoma of the head and neck. CANCER, 92(2), 326–331. -
Clinical trials referral resource: Current clinical trials of epothilone B analog (BMS-247550)
Colevas, A. D., West, P. J., & Cheson, B. D. (2001). Clinical trials referral resource: Current clinical trials of epothilone B analog (BMS-247550). ONCOLOGY-NEW YORK, 15(9), 1168-? -
Hypothyroidism incidence after multimodality treatment for stage III and IV squamous cell carcinomas of the head and neck
Colevas, A. D., Read, R., Thornhill, J., Adak, S., Tishler, R., Busse, P., … Posner, M. (2001). Hypothyroidism incidence after multimodality treatment for stage III and IV squamous cell carcinomas of the head and neck. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 51(3), 599–604. -
Phase I/II trial of outpatient docetaxel, cisplatin, 5-fluorouracil, leucovorin (opTPFL) as induction for squamous cell carcinoma of the head and neck (SCCHN)
Colevas, A. D., Norris, C. M., Tishler, R. B., Lamb, C. C., Fried, M. P., Goguen, L. A., … Posner, M. R. (2002). Phase I/II trial of outpatient docetaxel, cisplatin, 5-fluorouracil, leucovorin (opTPFL) as induction for squamous cell carcinoma of the head and neck (SCCHN). AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 25(2), 153–159. -
A Phase I/II trial of concurrent docetaxel and radiation after induction chemotherapy in patients with poor prognosis squamous cell carcinoma of the head and neck
Tishler, R. B., Norris, C. M., Colevas, A. D., Lamb, C. C., Karp, D., Busse, P. M., … Posner, M. R. (2002). A Phase I/II trial of concurrent docetaxel and radiation after induction chemotherapy in patients with poor prognosis squamous cell carcinoma of the head and neck. CANCER, 95(7), 1472–1481. -
Docetaxel, cisplatin, and 5-fluorouracil-based induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck - The Dana Farber Cancer Institute experience
Haddad, R., Colevas, A. D., Tishler, R., Busse, P., Goguen, L., Sullivan, C., … Posner, M. (2003). Docetaxel, cisplatin, and 5-fluorouracil-based induction chemotherapy in patients with locally advanced squamous cell carcinoma of the head and neck - The Dana Farber Cancer Institute experience. CANCER, 97(2), 412–418. -
Timed sequential therapy of acute leukemia with flavopiridol: In vitro model for a phase I clinical trial
Karp, J. E., Ross, D. D., Yang, W. D., Tidwell, M. L., Wei, Y. T., Greer, J., … Colevas, A. D. (2003). Timed sequential therapy of acute leukemia with flavopiridol: In vitro model for a phase I clinical trial. CLINICAL CANCER RESEARCH, 9(1), 307–315. -
Organ preservation-induction chemotherapy.
Colevas, A. D. (2003). Organ preservation-induction chemotherapy. Cancer Treatment and Research, 114, 213–234. -
Development of investigational radiation modifiers
Colevas, A. D., Brown, J. M., Hahn, S., Mitchell, J., Camphausen, K., & Coleman, C. N. (2003). Development of investigational radiation modifiers. JOURNAL OF THE NATIONAL CANCER INSTITUTE, 95(9), 646–51. -
CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment
Trotti, A., Colevas, A. D., SETSER, A., Rusch, V., Jaques, D., Budach, V., … Rubin, P. (2003). CTCAE v3.0: Development of a comprehensive grading system for the adverse effects of cancer treatment. SEMINARS IN RADIATION ONCOLOGY, 13(3), 176–181. -
Herceptin in patients with advanced or metastatic salivary gland carcinomas. A phase II study
Haddad, R., Colevas, A. D., Krane, J. F., Cooper, D., Glisson, B., Amrein, P. C., … Posner, M. (2003). Herceptin in patients with advanced or metastatic salivary gland carcinomas. A phase II study. ORAL ONCOLOGY, 39(7), 724–727. -
HER2 expression in salivary gland carcinomas: Dependence on histological subtype
Glisson, B., Colevas, A. D., Haddad, R., Krane, J., El-Naggar, A., Kies, M., … Posner, M. (2004). HER2 expression in salivary gland carcinomas: Dependence on histological subtype. CLINICAL CANCER RESEARCH, 10(3), 944–946. -
Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma
Burdette-Radoux, S., Tozer, R. G., Lohmann, R. C., Quirt, I., Ernst, D. S., Walsh, W., … Eisenhauer, E. A. (2004). Phase II trial of flavopiridol, a cyclin dependent kinase inhibitor, in untreated metastatic malignant melanoma. INVESTIGATIONAL NEW DRUGS, 22(3), 315–322. -
The clinical development of new mitotic inhibitors that stabilize the microtubule
Mani, S., Macapinlac, M., Goel, S., Verdier-Pinard, D., Fojo, T., Rothenberg, M., & Colevas, D. (2004). The clinical development of new mitotic inhibitors that stabilize the microtubule. ANTI-CANCER DRUGS, 15(6), 553–58. -
Current clinical trials of cilengitide, an alpha(v) antagonist in clinical development as an anticancer agent
Colevas, A. D., Scharf, O., & Schoenfeldt, M. (2004). Current clinical trials of cilengitide, an alpha(v) antagonist in clinical development as an anticancer agent. ONCOLOGY-NEW YORK, 18(14), 1778-? -
Multi-institutional randomized phase II trial of the epothilone B analog ixabepilone (BMS-247550) with or without estramustine phosphate in patients with progressive castrate metastatic prostate cancer
Galsky, M. D., Small, E. J., Oh, W. K., Chen, I., Smith, D. C., Colevas, A. D., … Kelly, W. K. (2005). Multi-institutional randomized phase II trial of the epothilone B analog ixabepilone (BMS-247550) with or without estramustine phosphate in patients with progressive castrate metastatic prostate cancer. JOURNAL OF CLINICAL ONCOLOGY, 23(7), 1439–1446. -
Phase I trial and pharmacokinetics of escalating doses of paclitaxel and concurrent hyperfractionated radiotherapy with or without amifostine in patients with advanced head and neck carcinoma
Amrein, P. C., Clark, J. R., Supko, J. G., Fabian, R. L., Wang, C. C., Colevas, A. D., … McIntyre, J. F. (2005). Phase I trial and pharmacokinetics of escalating doses of paclitaxel and concurrent hyperfractionated radiotherapy with or without amifostine in patients with advanced head and neck carcinoma. CANCER, 104(7), 1418–1427. -
Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: A southwest oncology group trial S0111
Hussain, M., Tangen, C. M., Lara, P. N., Vaishampayan, U. N., Petrylak, D. P., Colevas, A. D., … Crawford, E. D. (2005). Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: A southwest oncology group trial S0111. JOURNAL OF CLINICAL ONCOLOGY, 23(34), 8724–8729. -
Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias
Karp, J. E., Passaniti, A., Gojo, I., Kaufmann, S., Bible, K., Garimella, T. S., … Bauer, K. S. (2005). Phase I and pharmacokinetic study of flavopiridol followed by 1-beta-D-arabinofuranosylcytosine and mitoxantrone in relapsed and refractory adult acute leukemias. CLINICAL CANCER RESEARCH, 11(23), 8403–8412. -
In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent
Rudek, M. A., Zhao, M., Smith, N. F., Robey, R. W., He, P., Hallur, G., … Baker, S. D. (2005). In vitro and in vivo clinical pharmacology of dimethyl benzoylphenylurea, a novel oral tubulin-interactive agent. CLINICAL CANCER RESEARCH, 11(23), 8503–8511. -
Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: Scientific rationale and study design
Beekman, K. W., Colevas, A. D., Cooney, K., DiPaola, R., Dunn, R. L., Gross, M., … Hussain, M. (2006). Phase II evaluations of cilengitide in asymptomatic patients with androgen-independent prostate cancer: Scientific rationale and study design. CLINICAL GENITOURINARY CANCER, 4(4), 299–302. -
Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck
Colevas, A. D. (2006). Chemotherapy options for patients with metastatic or recurrent squamous cell carcinoma of the head and neck. JOURNAL OF CLINICAL ONCOLOGY, 24(17), 2644–2652. -
Adverse event reporting in publications compared with sponsor database for cancer clinical trials
Scharf, O., & Colevas, A. D. (2006). Adverse event reporting in publications compared with sponsor database for cancer clinical trials. JOURNAL OF CLINICAL ONCOLOGY, 24(24), 3933–3938. -
Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia
Byrd, J. C., Lin, T. S., Dalton, J. T., Wu, D., Phelps, M. A., Fischer, B., … Grever, M. R. (2007). Flavopiridol administered using a pharmacologically derived schedule is associated with marked clinical efficacy in refractory, genetically high-risk chronic lymphocytic leukemia. BLOOD, 109(2), 399–404. -
Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours
Messersmith, W. A., Rudek, M. A., Baker, S. D., Zhao, M., Collins, C., Colevas, A. D., … Wolff, A. C. (2007). Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours. EUROPEAN JOURNAL OF CANCER, 43(1), 78–86. -
A phase I trial of BMS-247550 (NSC# 710428) and gemcitabine in patients with advanced solid tumors
Hensley, M. L., Dizon, D., Derosa, F., Venkatraman, E., Sabbatini, P., Chi, D. S., … Aghajanian, C. (2007). A phase I trial of BMS-247550 (NSC# 710428) and gemcitabine in patients with advanced solid tumors. INVESTIGATIONAL NEW DRUGS, 25(4), 335–341. -
A phase II study of ixabepilone (BMS-247550) in metastatic renal-cell carcinoma
Posadas, E. M., Undevia, S., Manchen, E., Wade, J. L., Colevas, A. D., Karrison, T., … Stadler, W. M. (2007). A phase II study of ixabepilone (BMS-247550) in metastatic renal-cell carcinoma. CANCER BIOLOGY & THERAPY, 6(4), 490–493. -
Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma
Nabors, L. B., Mikkelsen, T., Rosenfeld, S. S., Hochberg, F., Akella, N. S., Fisher, J. D., … Grossman, S. A. (2007). Phase I and correlative biology study of cilengitide in patients with recurrent malignant glioma. JOURNAL OF CLINICAL ONCOLOGY, 25(13), 1651–1657. -
Inhibition of poly (ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models
Albert, J. M., Cao, C., Kim, K. W., Willey, C. D., Geng, L., Xiao, D., … Lu, B. (2007). Inhibition of poly (ADP-ribose) polymerase enhances cell death and improves tumor growth delay in irradiated lung cancer models. CLINICAL CANCER RESEARCH, 13(10), 3033–3042. -
Sequential flavopiridol, cytosine arabinoside, and mitoxantrone: A phase II trial in adults with poor-risk acute myelogenous leukemia
Karp, J. E., Smith, B. D., Levis, M. J., Gore, S. D., Greer, J., Hattenburg, C., … Colevas, A. D. (2007). Sequential flavopiridol, cytosine arabinoside, and mitoxantrone: A phase II trial in adults with poor-risk acute myelogenous leukemia. CLINICAL CANCER RESEARCH, 13(15), 4467–4473. -
Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer
Posner, M. R., Hershock, D. M., Blajman, C. R., Mickiewicz, E., Winquist, E., Gorbounova, V., … Haddad, R. I. (2007). Cisplatin and fluorouracil alone or with docetaxel in head and neck cancer. NEW ENGLAND JOURNAL OF MEDICINE, 357(17), 1705–1715. -
Patient-reported outcomes and the evolution of adverse event reporting in oncology
Trotti, A., Colevas, A. D., Setser, A., & Basch, E. (2007). Patient-reported outcomes and the evolution of adverse event reporting in oncology. JOURNAL OF CLINICAL ONCOLOGY, 25(32), 5121–27. -
Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck
Tang, P. A., Siu, L. L., Chen, E. X., Hotte, S. J., Chia, S., Schwarz, J. K., … Winquist, E. (2008). Phase II study of ispinesib in recurrent or metastatic squamous cell carcinoma of the head and neck. INVESTIGATIONAL NEW DRUGS. ISTANBUL,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY,TURKEY: SPRINGER. -
A multicentre phase II clinical experience with the novel aza-epothilone Ixabepilone (BMS247550) in patients with relapsed or refractory indolent non-Hodgkin lymphoma and mantle cell lymphoma
O'Connor, O. A., Portlock, C., Moskowitz, C., Straus, D., Hamlin, P., Stubblefield, M., … Zelenetz, A. (2008). A multicentre phase II clinical experience with the novel aza-epothilone Ixabepilone (BMS247550) in patients with relapsed or refractory indolent non-Hodgkin lymphoma and mantle cell lymphoma. BRITISH JOURNAL OF HAEMATOLOGY, 143(2), 201–209. -
Head and neck cancers.
Forastiere, A. A., Ang, K.-K., Brizel, D., Brockstein, B. E., Burtness, B. A., Cmelak, A. J., … Worden, F. (2008). Head and neck cancers. Journal of the National Comprehensive Cancer Network , 6(7), 646–695. -
LONG-TERM OUTCOMES AND TOXICITY OF CONCURRENT PACLITAXEL AND RADIOTHERAPY FOR LOCALLY ADVANCED HEAD-AND-NECK CANCER
Citrin, D., Mansueti, J., Likhacheva, A., Sciuto, L., Albert, P. S., Rudy, S. F., … Van Waes, C. (2009). LONG-TERM OUTCOMES AND TOXICITY OF CONCURRENT PACLITAXEL AND RADIOTHERAPY FOR LOCALLY ADVANCED HEAD-AND-NECK CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 74(4), 1040–46. -
MOLECULAR AND CLINICAL RESPONSES IN A PILOT STUDY OF GEFITINIB WITH PACLITAXEL AND RADIATION IN LOCALLY ADVANCED HEAD-AND-NECK CANCER
Van Waes, C., Allen, C. T., Citrin, D., Gius, D., Colevas, A. D., Harold, N. A., … Morris, J. C. (2010). MOLECULAR AND CLINICAL RESPONSES IN A PILOT STUDY OF GEFITINIB WITH PACLITAXEL AND RADIATION IN LOCALLY ADVANCED HEAD-AND-NECK CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 77(2), 447–454. -
HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA
Filion, E. J., McClure, L. A., Huang, D., Seng, K., Kaplan, M. J., Colevas, A. D., … Le, Q.-T. (2010). HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 32(10), 1336–44. -
INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX
Daly, M. E., Le, Q.-T., Jain, A. K., Maxim, P. G., Hsu, A., Loo, B. W., … Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 33(1), 103–11. -
A Phase II First-Line Study of Gemcitabine, Carboplatin, and Bevacizumab in Advanced Stage Nonsquamous Non-small Cell Lung Cancer
Clement-Duchene, C., Krupitskaya, Y., Ganjoo, K., Lavori, P., McMillan, A., Kumar, A., … Wakelee, H. A. (2010). A Phase II First-Line Study of Gemcitabine, Carboplatin, and Bevacizumab in Advanced Stage Nonsquamous Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 5(11), 1821–25. -
Head and Neck Cancers
Pfister, D. G., Ang, K.-K., Brizel, D. M., Burtness, B. A., Cmelak, A. J., Colevas, D., … Worden, F. (2011). Head and Neck Cancers. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 9(6), 596–649. -
Controversies in the Locoregional Management of Head and Neck Cancer
Brizel, D. M., Lydiatt, W., & Colevas, A. D. (2011). Controversies in the Locoregional Management of Head and Neck Cancer. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 9(6), 653–62. -
Quantitation of Human Papillomavirus DNA in Plasma of Oropharyngeal Carcinoma Patients
Cao, H., Banh, A., Kwok, S., Shi, X., Wu, S., Krakow, T., … Quynh-Thu Le, Q. T. (2012). Quantitation of Human Papillomavirus DNA in Plasma of Oropharyngeal Carcinoma Patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 82(3), E351–E358. -
Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure
Wiegner, E. A., Daly, M. E., Murphy, J. D., Abelson, J., Chapman, C. H., Chung, M., … Chang, D. T. (2012). Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. SAN DIEGO,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA: ELSEVIER SCIENCE INC. -
A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib in patients with advanced solid tumors
Padda, S. K., Krupitskaya, Y., Chhatwani, L., Fisher, G. A., Colevas, A. D., Pedro-Salcedo, M. S., … Wakelee, H. A. (2012). A phase I dose-escalation and pharmacokinetic study of enzastaurin and erlotinib in patients with advanced solid tumors. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 69(4), 1013–20. -
Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial
Lee, N. Y., Zhang, Q., Pfister, D. G., Kim, J., Garden, A. S., Mechalakos, J., … Ang, K. K. (2012). Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial. LANCET ONCOLOGY, 13(2), 172–80. -
Validation that metabolic tumor volume predicts outcome in head-and-neck cancer.
Tang, C., Murphy, J. D., Khong, B., La, T. H., Kong, C., Fischbein, N. J., … Le, Q.-T. (2012). Validation that metabolic tumor volume predicts outcome in head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics, 83(5), 1514–20. -
Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer
Kohrt, H. E., Houot, R., Weiskopf, K., Goldstein, M. J., Scheeren, F., Czerwinski, D., … Levy, R. (2012). Stimulation of natural killer cells with a CD137-specific antibody enhances trastuzumab efficacy in xenotransplant models of breast cancer. JOURNAL OF CLINICAL INVESTIGATION, 122(3), 1066–75. -
Phase I trial of ixabepilone administered as three oral doses each separated by 6 hours every 3 weeks in patients with advanced solid tumors
Kunz, P. L., He, A. R., Colevas, A. D., Pishvaian, M. J., Hwang, J. J., Clemens, P. L., … Marshall, J. L. (2012). Phase I trial of ixabepilone administered as three oral doses each separated by 6 hours every 3 weeks in patients with advanced solid tumors. INVESTIGATIONAL NEW DRUGS, 30(6), 2364–70. -
Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl(+) hematological malignancies
Bose, P., Perkins, E. B., Honeycut, C., Wellons, M. D., Stefan, T., Jacobberger, J. W., … Grant, S. (2012). Phase I trial of the combination of flavopiridol and imatinib mesylate in patients with Bcr-Abl(+) hematological malignancies. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 69(6), 1657–67. -
Maintenance Bevacizumab is Associated With Increased Hemoglobin in Patients With Advanced, Nonsquamous, Non-Small Cell Lung Cancer
Riess, J. W., Logan, A. C., Krupitskaya, Y., Padda, S., Clement-Duchene, C., Ganjoo, K., … Wakelee, H. A. (2012). Maintenance Bevacizumab is Associated With Increased Hemoglobin in Patients With Advanced, Nonsquamous, Non-Small Cell Lung Cancer. CANCER INVESTIGATION, 30(3), 231–35. -
Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors
Trakul, N., Chang, C. N., Harris, J., Chapman, C., Rao, A., Shen, J., … Diehn, M. (2012). Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(1), 231–37. -
Mucosal Melanoma of the Head and Neck
Pfister, D. G., Ang, K.-K., Brizel, D. M., Burtness, B., Cmelak, A. J., Dimitrios Colevas, A., … Schuller, D. E. (2012). Mucosal Melanoma of the Head and Neck. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 10(3), 320–338. -
Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck.
Tang, C., Fischbein, N. J., Murphy, J. D., Chu, K. P., Bavan, B., Dieterich, S., … Le, Q.-T. (2013). Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck. American Journal of Clinical Oncology, 36(3), 293–98. -
A Phase 2 Trial of Flavopiridol (Alvocidib) and Cisplatin in Platin-Resistant Ovarian and Primary Peritoneal Carcinoma: MC0261
Bible, K. C., Peethambaram, P. P., Oberg, A. L., Maples, W., Groteluschen, D. L., Boente, M., … Erlichman, C. (2012). A Phase 2 Trial of Flavopiridol (Alvocidib) and Cisplatin in Platin-Resistant Ovarian and Primary Peritoneal Carcinoma: MC0261. GYNECOLOGIC ONCOLOGY, 127(1), 55–62. -
A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma
Kim, K. B., Prieto, V., Joseph, R. W., Diwan, A. H., Gallick, G. E., Papadopoulos, N. E., … Colevas, A. D. (2012). A randomized phase II study of cilengitide (EMD 121974) in patients with metastatic melanoma. MELANOMA RESEARCH, 22(4), 294–301. -
A phase I dose-escalation study of aflibercept administered in combination with pemetrexed and cisplatin in patients with advanced solid tumours
Diaz-Padilla, I., Siu, L. L., San Pedro-Salcedo, M., Razak, A. R. A., Colevas, A. D., Shepherd, F. A., … Wakelee, H. A. (2012). A phase I dose-escalation study of aflibercept administered in combination with pemetrexed and cisplatin in patients with advanced solid tumours. BRITISH JOURNAL OF CANCER, 107(4), 604–11. -
Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential
LoRusso, P. M., Piha-Paul, S. A., Mita, M., Colevas, A. D., Malhi, V., Colburn, D., … Graham, R. A. (2013). Co-administration of vismodegib with rosiglitazone or combined oral contraceptive in patients with locally advanced or metastatic solid tumors: a pharmacokinetic assessment of drug-drug interaction potential. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 71(1), 193–202. -
The use of epidermal growth factor receptor monoclonal antibodies in squamous cell carcinoma of the head and neck.
Russell, J. S., & Colevas, A. D. (2012). The use of epidermal growth factor receptor monoclonal antibodies in squamous cell carcinoma of the head and neck. Chemotherapy Research and Practice, 2012, 761518-? -
Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence.
Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., Colevas, A. D., … Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. Cancer, 119(7), 1349–56. -
Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma.
Danial, C., Lingala, B., Balise, R., Oro, A. E., Reddy, S., Colevas, A., & Chang, A. L. S. (2013). Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma. British Journal of Dermatology, 169(3), 673–76. -
Long-Term Outcomes of Surgery Followed by Radiation Therapy for Minor Salivary Gland Carcinomas
Zeidan, Y. H., Shultz, D. B., Murphy, J. D., Chan, C., Kaplan, M. J., Colevas, A. D., … Le, Q.-T. (2013). Long-Term Outcomes of Surgery Followed by Radiation Therapy for Minor Salivary Gland Carcinomas. LARYNGOSCOPE, 123(11), 2675–80. -
Population-based evaluation of incidence trends in oropharyngeal cancer focusing on socioeconomic status, sex, and race/ethnicity
Colevas, A. D. (2014). Population-based evaluation of incidence trends in oropharyngeal cancer focusing on socioeconomic status, sex, and race/ethnicity. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 36(1), 34–42. -
Biased View of the Role of Site-Specific Therapy in Carcinoma of Unknown Primary.
Percival, M.-E. E., & Colevas, A. D. (2013). Biased View of the Role of Site-Specific Therapy in Carcinoma of Unknown Primary. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. -
Future directions in the treatment of squamous cell carcinoma of the head and neck: the role of UFT.
Colevas, A. D. (1997). Future directions in the treatment of squamous cell carcinoma of the head and neck: the role of UFT. Oncology (Williston Park, N.Y.), 11(9), 86–89. -
Induction chemotherapy with docetaxel, cisplatin, fluorouracil, and leucovorin for squamous cell carcinoma of the head and neck: A phase I/II trial
Colevas, A. D., Busse, P. M., Norris, C. M., Fried, M., Tishler, R. B., Poulin, M., … Posner, M. R. (1998). Induction chemotherapy with docetaxel, cisplatin, fluorouracil, and leucovorin for squamous cell carcinoma of the head and neck: A phase I/II trial. JOURNAL OF CLINICAL ONCOLOGY, 16(4), 1331–1339. -
Docetaxel in head and neck cancer - A review
Colevas, A. D., & Posner, M. R. (1998). Docetaxel in head and neck cancer - A review. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 21(5), 482–486. -
Intramucosal spread of malignant melanoma of the oral cavity
Bhattacharyya, N., Norris, C. M., Colevas, A. D., & Chasse, T. A. (1998). Intramucosal spread of malignant melanoma of the oral cavity. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 119(6), 711–711. -
ECOG 1308: A phase II trial of induction chemotherapy followed by cetuximab with low dose versus standard dose IMRT in patients with HPV-associated resectable squamous cell carcinoma of the oropharynx (OP).
Marur, S., Lee, J.-W., Cmelak, A., Zhao, W., Westra, W. H., Chung, C. H., … Burtness, B. (2012). ECOG 1308: A phase II trial of induction chemotherapy followed by cetuximab with low dose versus standard dose IMRT in patients with HPV-associated resectable squamous cell carcinoma of the oropharynx (OP). JOURNAL OF CLINICAL ONCOLOGY, 30(15). -
Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab
Kohrt, H. E., Houot, R., Weiskopf, K., Goldstein, M., Lund, P., Scheeren, F., … Levy, R. (2012). Effect of stimulation of natural killer cells with an anti-CD137 mAb on the efficacy of trastuzumab, cetuximab, and rituximab. JOURNAL OF CLINICAL ONCOLOGY, 30(15). -
Quantification of pre-treatment metabolic tumor growth rate in lung cancer
Eastham, D., Chapman, C. H., Rao, A. K., Balasubramanian, N., Quon, A., Vasanawala, M. S., … Loo, B. W. (2009). Quantification of pre-treatment metabolic tumor growth rate in lung cancer. JOURNAL OF THORACIC ONCOLOGY, 4(9), S733–S733. -
Does Pre-treatment Metabolic Tumor Growth Rate (MTGR) Predict Progression in Lung Cancer?
Eastham, D. V., Chapman, C. H., Rao, A. K., Narasimhan, B., Quon, A., Vasanawala, M. S., … Loo, B. W. (2009). Does Pre-treatment Metabolic Tumor Growth Rate (MTGR) Predict Progression in Lung Cancer? INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 75(3), S446–S446. -
Excellent early local control with tumor volume adapted dosing of stereotactic body radiation therapy for pulmonary tumors
Chang, C. N., Zhou, L. Y., MacFarlane, G., Tran, P., Rao, A., Chapman, C., … Loo, B. W. (2009). Excellent early local control with tumor volume adapted dosing of stereotactic body radiation therapy for pulmonary tumors. JOURNAL OF THORACIC ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Phase Ib, multicenter, single-blinded, placebo-controlled, sequential dose-escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer (LAHNC) receiving induction chemotherapy (ICT).
Limaye, S. A., Sonis, S. T., Cilli, F., Colevas, A. D., Brennan, M., Hu, K., … Murphy, B. A. (2012). Phase Ib, multicenter, single-blinded, placebo-controlled, sequential dose-escalation study to assess the safety and tolerability of topically applied AG013 in subjects with locally advanced head and neck cancer (LAHNC) receiving induction chemotherapy (ICT). JOURNAL OF CLINICAL ONCOLOGY, 30(15). -
Long term followup of a phase I study of concurrent paclitaxel and radiation for locally advanced squamous cell carcinoma of the head and neck
Mansueti, J., Likhacheva, A., Albert, P., Scuito, L., Harold, N., Rudy, S., … Citrin, D. (2007). Long term followup of a phase I study of concurrent paclitaxel and radiation for locally advanced squamous cell carcinoma of the head and neck. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(3), S444–S444. -
Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma
Danial, C., Lingala, B., Balise, R., Oro, A. E., Reddy, S., Colevas, A., & Chang, A. L. S. (2013). Markedly improved overall survival in 10 consecutive patients with metastatic basal cell carcinoma. BRITISH JOURNAL OF DERMATOLOGY, 169(3), 673–76. -
Head and Neck Cancers, Version 2.2013 Featured Updates to the NCCN Guidelines
Pfister, D. G., Ang, K.-K., Brizel, D. M., Burtness, B. A., Busse, P. M., Caudell, J. J., … Hughes, M. (2013). Head and Neck Cancers, Version 2.2013 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 11(8), 917–23. -
Phase 1b, Multicenter, Single Blinded, Placebo-Controlled, Sequential Dose Escalation Study to Assess the Safety and Tolerability of Topically Applied AG013 in Subjects With Locally Advanced Head and Neck Cancer Receiving Induction Chemotherapy
Limaye, S. A., Haddad, R. I., Cilli, F., Sonis, S. T., Colevas, A. D., Brennan, M. T., … Murphy, B. A. (2013). Phase 1b, Multicenter, Single Blinded, Placebo-Controlled, Sequential Dose Escalation Study to Assess the Safety and Tolerability of Topically Applied AG013 in Subjects With Locally Advanced Head and Neck Cancer Receiving Induction Chemotherapy. CANCER, 119(24), 4268–76. -
Targeting CD137 enhances the efficacy of cetuximab.
Kohrt, H. E., Colevas, A. D., Houot, R., Weiskopf, K., Goldstein, M. J., Lund, P., … Levy, R. (2014). Targeting CD137 enhances the efficacy of cetuximab. Journal of Clinical Investigation, 124(6), 2668–2682. -
Targeting CD137 enhances the efficacy of cetuximab.
Kohrt, H. E., Colevas, A. D., Houot, R., Weiskopf, K., Goldstein, M. J., Lund, P., … Levy, R. (2014). Targeting CD137 enhances the efficacy of cetuximab. Journal of Clinical Investigation, 124(6), 2668–82. -
Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines.
Pfister, D. G., Ang, K.-K., Brizel, D. M., Burtness, B. A., Busse, P. M., Caudell, J. J., … Hughes, M. (2013). Head and neck cancers, version 2.2013. Featured updates to the NCCN guidelines. Journal of the National Comprehensive Cancer Network , 11(8), 917–923. -
CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.
Murillo-Sauca, O., Chung, M. K., Shin, J. H., Karamboulas, C., Kwok, S., Jung, Y. H., … Sunwoo, J. B. (2014). CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma. Oncotarget, 5(16), 6854–66. -
Hearing evaluation of patients with head and neck cancer: Comparison of Common Terminology Criteria for Adverse Events, Brock and Chang adverse event criteria in patients receiving cisplatin.
Colevas, A. D., Lira, R. R., Colevas, E. A., Lavori, P. W., Chan, C., Shultz, D. B., & Chang, K. W. (2015). Hearing evaluation of patients with head and neck cancer: Comparison of Common Terminology Criteria for Adverse Events, Brock and Chang adverse event criteria in patients receiving cisplatin. Head & Neck, 37(8), 1102–7. -
Head and Neck Cancers, Version 2.2014
Pfister, D. G., Spencer, S., Brizel, D. M., Burtness, B., Busse, P. M., Caudell, J. J., … Hughes, M. (2014). Head and Neck Cancers, Version 2.2014. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 12(10), 1454–87. -
Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology.
Pfister, D. G., Spencer, S., Brizel, D. M., Burtness, B., Busse, P. M., Caudell, J. J., … Hughes, M. (2014). Head and neck cancers, Version 2.2014. Clinical practice guidelines in oncology. Journal of the National Comprehensive Cancer Network , 12(10), 1454–1487. -
Concurrent cetuximab versus platinum-based chemoradiation for the definitive treatment of locoregionally advanced head and neck cancer.
Tang, C., Chan, C., Jiang, W., Murphy, J. D., von Eyben, R., Colevas, A. D., … Le, Q.-T. (2015). Concurrent cetuximab versus platinum-based chemoradiation for the definitive treatment of locoregionally advanced head and neck cancer. Head & Neck, 37(3), 386–92. -
Differentiated Thyroid Cancer: Focus on Emerging Treatments for Radioactive Iodine-Refractory Patients
Gruber, J. J., & Colevas, A. D. (2015). Differentiated Thyroid Cancer: Focus on Emerging Treatments for Radioactive Iodine-Refractory Patients. ONCOLOGIST, 20(2), 113–26. -
Ameloblastoma: a clinical review and trends in management
McClary, A. C., West, R. B., McClary, A. C., Pollack, J. R., Fischbein, N. J., Holsinger, C. F., … Sirjani, D. (2016). Ameloblastoma: a clinical review and trends in management. EUROPEAN ARCHIVES OF OTO-RHINO-LARYNGOLOGY, 273(7), 1649–61. -
Phase I Trial of Bortezomib (PS-341; NSC 681239) and "Nonhybrid" (Bolus) Infusion Schedule of Alvocidib (Flavopiridol; NSC 649890) in Patients with Recurrent or Refractory Indolent B-cell Neoplasms
Holkova, B., Kmieciak, M., Perkins, E. B., Bose, P., Baz, R. C., Roodman, G. D., … Grant, S. (2014). Phase I Trial of Bortezomib (PS-341; NSC 681239) and "Nonhybrid" (Bolus) Infusion Schedule of Alvocidib (Flavopiridol; NSC 649890) in Patients with Recurrent or Refractory Indolent B-cell Neoplasms. CLINICAL CANCER RESEARCH, 20(22), 5652–5662. -
A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma
Galloway, T. J., Wirth, L. J., Colevas, A. D., Gilbert, J., Bauman, J. E., Saba, N. F., … Jimeno, A. (2015). A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma. CLINICAL CANCER RESEARCH, 21(7), 1566–73. -
Concurrent Vismodegib and Radiotherapy for Recurrent, Advanced Basal Cell Carcinoma.
Pollom, E. L., Bui, T. T., Chang, A. L. S., Colevas, A. D., & Hara, W. Y. (2015). Concurrent Vismodegib and Radiotherapy for Recurrent, Advanced Basal Cell Carcinoma. JAMA Dermatology, 151(9), 998–1001. -
Advances in Nanotechnology and Microfluidics for Human Papillomavirus Diagnostics
Tasoglu, S., Tekin, H. C., Inci, F., Knowlton, S., Wang, S., Wang-Johanning, F., … Demirci, U. (2015). Advances in Nanotechnology and Microfluidics for Human Papillomavirus Diagnostics. PROCEEDINGS OF THE IEEE, 103(2), 161–78. -
Head and Neck Cancers, Version 1.2015.
Pfister, D. G., Spencer, S., Brizel, D. M., Burtness, B., Busse, P. M., Caudell, J. J., … Hughes, M. (2015). Head and Neck Cancers, Version 1.2015. Journal of the National Comprehensive Cancer Network , 13(7), 847–56. -
Head and Neck Cancers, Version 1.2015 Featured Updates to the NCCN Guidelines
Pfister, D. G., Spencer, S., Brizel, D. M., Burtness, B., Busse, P. M., Caudell, J. J., … Hughes, M. (2015). Head and Neck Cancers, Version 1.2015 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 13(7), 847–56. -
Balancing Safety and Efficacy of Epidermal Growth Factor Receptor Inhibitors in Patients With Squamous Cell Carcinoma of the Head and Neck
Iberri, D. J., & Colevas, A. D. (2015). Balancing Safety and Efficacy of Epidermal Growth Factor Receptor Inhibitors in Patients With Squamous Cell Carcinoma of the Head and Neck. ONCOLOGIST, 20(12), 1393–1403. -
A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers.
Pollom, E. L., Wang, E., Bui, T. T., Ognibene, G., von Eyben, R., Divi, V., … Hara, W. Y. (2015). A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers. Oral Oncology, 51(12), 1132–37. -
Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma.
Ally, M. S., Ransohoff, K., Sarin, K., Atwood, S. X., Rezaee, M., Bailey-Healy, I., … Colevas, A. D. (2016). Effects of Combined Treatment With Arsenic Trioxide and Itraconazole in Patients With Refractory Metastatic Basal Cell Carcinoma. JAMA Dermatology, 152(4), 452–56. -
Effects of combined treatment with arsenic trioxide and itraconazole in patients with refractory metastatic basal cell carcinoma
Sarin, K. Y., Ally, M. S., Ransohoff, K. J., Atwood, S. X., & Rezaee, M. (2016). Effects of combined treatment with arsenic trioxide and itraconazole in patients with refractory metastatic basal cell carcinoma. JAMA Dermatology, 1–5. -
Discordance in routine second opinion pathology review of head and neck oncology specimens: A single-center five year retrospective review
Zhu, G. A., Lira, R., & Colevas, A. D. (2016). Discordance in routine second opinion pathology review of head and neck oncology specimens: A single-center five year retrospective review. ORAL ONCOLOGY, 53, 36–41. -
NCCN Oncology Research Program's Investigator Steering Committee and NCCN Best Practices Committee Molecular Profiling Surveys
Kurzrock, R., Colevas, A. D., Olszanski, A., Akerley, W., Arteaga, C. L., Carson, W. E., … Stewart, F. M. (2015). NCCN Oncology Research Program's Investigator Steering Committee and NCCN Best Practices Committee Molecular Profiling Surveys. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 13(11), 1337–46. -
Pharmacodynamics (PD) and pharmacokinetics (PK) of E7389 (eribulin, halichondrin B analog) during a phase I trial in patients with advanced solid tumors: a California Cancer Consortium trial
Morgan, R. J., Synold, T. W., Longmate, J. A., Quinn, D. I., Gandara, D., Lenz, H.-J., … Newman, E. M. (2015). Pharmacodynamics (PD) and pharmacokinetics (PK) of E7389 (eribulin, halichondrin B analog) during a phase I trial in patients with advanced solid tumors: a California Cancer Consortium trial. CANCER CHEMOTHERAPY AND PHARMACOLOGY, 76(5), 897–907. -
Concurrent Vismodegib and Radiotherapy for Recurrent, Advanced Basal Cell Carcinoma.
Pollom, E. L., Bui, T. T., Chang, A. L. S., Colevas, A. D., & Hara, W. Y. (2015). Concurrent Vismodegib and Radiotherapy for Recurrent, Advanced Basal Cell Carcinoma. JAMA Dermatology, 151(9), 998–1001. -
Proposal for the 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy.
Pan, J. J., Ng, W. T., Zong, J. F., Chan, L. L. K., O'Sullivan, B., Lin, S. J., … Lee, A. W. M. (2016). Proposal for the 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy. Cancer, 122(4), 546–58. -
Design and rationale of a prospective multi-institutional registry for patients with sinosodal malignancy
Beswick, D. M., Holsinger, F. C., Kaplan, M. J., Fischbein, N. J., Hara, W. Y., Colevas, A. D., … Hwang, P. H. (2016). Design and rationale of a prospective multi-institutional registry for patients with sinosodal malignancy. The Laryngoscope, ([Epub ahead of print]). -
Design and rationale of a prospective, multi-institutional registry for patients with sinonasal malignancy.
Beswick, D. M., Holsinger, F. C., Kaplan, M. J., Fischbein, N. J., Hara, W., Colevas, A. D., … Hwang, P. H. (2016). Design and rationale of a prospective, multi-institutional registry for patients with sinonasal malignancy. Laryngoscope, 126(9), 1977–80. -
Number of positive nodes is superior to the lymph node ratio and American Joint Committee on Cancer N staging for the prognosis of surgically treated head and neck squamous cell carcinomas
Roberts, T. J., Colevas, A. D., Hara, W., Holsinger, F. C., Oakley-Girvan, I., & Divi, V. (2016). Number of positive nodes is superior to the lymph node ratio and American Joint Committee on Cancer N staging for the prognosis of surgically treated head and neck squamous cell carcinomas. CANCER, 122(9), 1388–97. -
BRAF inhibitor treatment of primary BRAF-mutant ameloblastoma with pathologic assessment of response
Tan, S., Pollack, J. R., Kaplan, M. J., Colevas, A. D., & West, R. B. (2016). BRAF inhibitor treatment of primary BRAF-mutant ameloblastoma with pathologic assessment of response. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 122(1), E5–E7. -
Third party assessment of resection margin status in head and neck cancer.
Ransohoff, A., Wood, D., Solomon Henry, A., Divi, V., & Colevas, A. (2016). Third party assessment of resection margin status in head and neck cancer. Oral Oncology, 57, 27–31. -
Current Standards in Treatment of Radioiodine Refractory Thyroid Cancer
Narayanan, S., & Colevas, A. D. (2016). Current Standards in Treatment of Radioiodine Refractory Thyroid Cancer. CURRENT TREATMENT OPTIONS IN ONCOLOGY, 17(6). -
A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors.
Rosen, L. S., LoRusso, P., Ma, W. W., Goldman, J. W., Weise, A., Colevas, A. D., … Sikic, B. I. (2016). A first-in-human phase I study to evaluate the MEK1/2 inhibitor, cobimetinib, administered daily in patients with advanced solid tumors. Investigational New Drugs, 34(5), 604–13. -
Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence
Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., Colevas, A. D., … Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. CANCER, 119(7), 1349–56. -
Validation that Metabolic Tumor Volume Predicts Outcome in Head-and-Neck Cancer
Tang, C., Murphy, J. D., Khong, B., La, T. H., Kong, C., Fischbein, N. J., … Quynh-Thu Le, Q. T. (2012). Validation that Metabolic Tumor Volume Predicts Outcome in Head-and-Neck Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), 1514–20. -
Prognostic nomogram for refining the prognostication of the proposed 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy.
Pan, J. J., Ng, W. T., Zong, J. F., Lee, S. W. M., Choi, H. C. W., Chan, L. L. K., … Lee, A. W. M. (2016). Prognostic nomogram for refining the prognostication of the proposed 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy. Cancer, 122(21), 3307–15. -
Follow-up on Programmed Cell Death 1 Inhibitor for Cutaneous Squamous Cell Carcinoma.
Tran, D. C., Colevas, A. D., & Chang, A. L. S. (2016). Follow-up on Programmed Cell Death 1 Inhibitor for Cutaneous Squamous Cell Carcinoma. JAMA Dermatology. -
Eruptive Keratoacanthomas Associated With Pembrolizumab Therapy.
Freites-Martinez, A., Kwong, B. Y., Rieger, K. E., Coit, D. G., Colevas, A. D., & Lacouture, M. E. (2017). Eruptive Keratoacanthomas Associated With Pembrolizumab Therapy. JAMA Dermatology. -
Characterizing CD137 Upregulation on NK cells in Patients Receiving Monoclonal Antibody Therapy.
MAKKOUK, A., Sundaram, V., Chester, C., Chang, S., Colevas, A. D., Sunwoo, J. B., … Kohrt, H. E. (2016). Characterizing CD137 Upregulation on NK cells in Patients Receiving Monoclonal Antibody Therapy. Annals of Oncology . -
Third party assessment of resection margin status in head and neck cancer
Ransohoff, A., Wood, D., Henry, A. S., Divi, V., & Colevas, A. (2016). Third party assessment of resection margin status in head and neck cancer. ORAL ONCOLOGY, 57, 27–31. -
Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes.
Amoils, M., Lee, C. S., Sunwoo, J., Aasi, S. Z., Hara, W., Kim, J., … Divi, V. (2017). Node-positive cutaneous squamous cell carcinoma of the head and neck: Survival, high-risk features, and adjuvant chemoradiotherapy outcomes. Head & Neck. -
E1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx- ECOG-ACRIN Cancer Research Group.
Marur, S., Li, S., Cmelak, A. J., Gillison, M. L., Zhao, W. J., Ferris, R. L., … Burtness, B. (2016). E1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx- ECOG-ACRIN Cancer Research Group. Journal of Clinical Oncology , JCO2016683300-? -
Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
Ferris, R. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Gillison, M. L. (2016). Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck. NEW ENGLAND JOURNAL OF MEDICINE, 375(19), 1856–67. -
Transsphenoidal Resection of Sellar Tumors Using High-Field Intraoperative Magnetic Resonance Imaging
Szerlip, N. J., Zhang, Y.-C., Placantonakis, D. G., Goldman, M., Colevas, K. B., Rubin, D. G., … Tabar, V. (2011). Transsphenoidal Resection of Sellar Tumors Using High-Field Intraoperative Magnetic Resonance Imaging. SKULL BASE-AN INTERDISCIPLINARY APPROACH, 21(4), 223–32. -
Peripheral blood mononuclear and tumor cell pharmacodynamics of the novel epothilone B analogue, ixabepilone
Mani, S., McDaid, H. M., Grossman, A., Muggia, F., Goel, S., Griffin, T., … Egorin, M. J. (2007). Peripheral blood mononuclear and tumor cell pharmacodynamics of the novel epothilone B analogue, ixabepilone. ANNALS OF ONCOLOGY, 18(1), 190–95. -
Phase I clinical trial of BMS-247550, a derivative of epothilone B, using accelerated titration 213 design
Gadgeel, S. M., Wozniak, A., Boinpally, R. R., Wiegand, R., Heilbrun, L. K., Jain, V., … LoRusso, P. M. (2005). Phase I clinical trial of BMS-247550, a derivative of epothilone B, using accelerated titration 213 design. CLINICAL CANCER RESEARCH, 11(17), 6233–39. -
Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy
MAKKOUK, A., Sundaram, V., Chester, C., Chang, S., Colevas, A. D., Sunwoo, J. B., … Kohrt, H. E. (2017). Characterizing CD137 upregulation on NK cells in patients receiving monoclonal antibody therapy. ANNALS OF ONCOLOGY, 28(2), 415–20. -
E1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx-ECOG-ACRIN Cancer Research Group
Marur, S., Li, S., Cmelak, A. J., Gillison, M. L., Zhao, W. J., Ferris, R. L., … Burtness, B. (2017). E1308: Phase II Trial of Induction Chemotherapy Followed by Reduced-Dose Radiation and Weekly Cetuximab in Patients With HPV-Associated Resectable Squamous Cell Carcinoma of the Oropharynx-ECOG-ACRIN Cancer Research Group. AMERICAN JOURNAL OF PSYCHOLOGY, 130(1), 490–U169. -
Comparative Effectiveness of Cetuximab or Cisplatin With Concomitant Radiation for Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck: A Population-Based Analysis
Xiang, M., Holsinger, F. C., Chen, M. M., Colevas, A. D., & Beadle, B. M. (2018). Comparative Effectiveness of Cetuximab or Cisplatin With Concomitant Radiation for Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck: A Population-Based Analysis. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 100(5), 1322. -
Panitumumab-IRDye800 as an Optical Agent for Image-Guided Surgery in Patients With Squamous Cell Carcinoma
Gao, R. W., Teraphongphom, N., van den Berg, N. S., Hong, S., Martin, B. A., Divi, V., … Rosenthal, E. L. (2018). Panitumumab-IRDye800 as an Optical Agent for Image-Guided Surgery in Patients With Squamous Cell Carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 100(5), 1312–13. -
Survival Benefit of Postoperative Chemotherapy for Intermediate-Risk Advanced Stage Head and Neck Cancer
Chen, M. M., Colevas, A. D., Megwalu, U., & Divi, V. (2018). Survival Benefit of Postoperative Chemotherapy for Intermediate-Risk Advanced Stage Head and Neck Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 100(5), 1326. -
Postoperative Radiation Therapy for Minor Salivary Gland Carcinomas of the Head and Neck: Long-term Outcomes
Zeidan, Y., Murphy, J. D., Chan, C., An, Y., Kaplan, M., Colevas, A., … Le, Q. (2012). Postoperative Radiation Therapy for Minor Salivary Gland Carcinomas of the Head and Neck: Long-term Outcomes. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(3), S500. -
Intensity modulated radiotherapy for squamous cell carcinoma of the hypopharynx and larynx: Clinical outcomes and patterns of failure
Daly, M. E., Le, Q. T., Loo, B. W., Maxim, P. G., Pinto, H. A., Colevas, A. D., … Chang, D. T. (2008). Intensity modulated radiotherapy for squamous cell carcinoma of the hypopharynx and larynx: Clinical outcomes and patterns of failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72(1), S405–S406. -
Regionally Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck: Survival and High-Risk Features
Amoils, M., Lee, C. S., Sunwoo, J., Aasi, S. Z., Hara, W., Kim, J., … Divi, V. (2016). Regionally Metastatic Cutaneous Squamous Cell Carcinoma of the Head and Neck: Survival and High-Risk Features. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
A Pilot Study of Electronic Quality of Life Assessments Using Tablet Devices During and After Treatment of Head and Neck Cancers
Wang, E., Pollom, E., Bui, T., Ognibene, G., von Eyben, R., Divi, V., … Hara, W. (2016). A Pilot Study of Electronic Quality of Life Assessments Using Tablet Devices During and After Treatment of Head and Neck Cancers. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 94(4), 969. -
A first-in-human phase 1 study to evaluate the MEK1/2 inhibitor GDC-0973 administered daily in patients with advanced solid tumors
Rosen, L., LoRusso, P., Ma, W. W., Goldman, J., Weise, A., Colevas, A. D., … Sikic, B. (2011). A first-in-human phase 1 study to evaluate the MEK1/2 inhibitor GDC-0973 administered daily in patients with advanced solid tumors. CANCER RESEARCH, 71. -
Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers
Gao, R. W., Teraphongphom, N., de Boer, E., van den Berg, N. S., Divi, V., Kaplan, M. J., … Rosenthal, E. L. (2018). Safety of panitumumab-IRDye800CW and cetuximab-IRDye800CW for fluorescence-guided surgical navigation in head and neck cancers. THERANOSTICS, 8(9), 2488–95. -
NCCN Guidelines (R) Insights Head and Neck Cancers, Version 1.2018 Featured Updates to the NCCN Guidelines
Colevas, A. D., Yom, S. S., Pfister, D. G., Spencer, S., Adelstein, D., Adkins, D., … Darlow, S. D. (2018). NCCN Guidelines (R) Insights Head and Neck Cancers, Version 1.2018 Featured Updates to the NCCN Guidelines. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 16(5), 479–90. -
A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy
Gubens, M. A., Chuang, J. C., Akerley, W., Langer, C. J., Clement-Duchene, C., San Pedro-Salcedo, M., … Wakelee, H. A. (2018). A pooled analysis of advanced nonsquamous non-small cell lung cancer patients with stable treated brain metastases in two phase II trials receiving bevacizumab and pemetrexed as second-line therapy. JOURNAL OF THORACIC DISEASE, 10(1), 219–27. -
Comparative Effectiveness and Toxicity of Cetuximab or Cisplatin With Concurrent Radiation for Locoregionally Advanced Squamous Cell Carcinoma of The Head And Neck: A Population-Based Analysis
Xiang, M., Holsinger, F. C., Chen, M., Colevas, A. D., & Beadle, B. M. (2018). Comparative Effectiveness and Toxicity of Cetuximab or Cisplatin With Concurrent Radiation for Locoregionally Advanced Squamous Cell Carcinoma of The Head And Neck: A Population-Based Analysis. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Two-year Update From CheckMate 141: Outcomes With Nivolumab (Nivo) vs Investigator's Choice (IC) in Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the Overall Population and PD-L1 Subgroups
Ferris, R. L., Blumenschein, G. R., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Gillison, M. (2018). Two-year Update From CheckMate 141: Outcomes With Nivolumab (Nivo) vs Investigator's Choice (IC) in Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the Overall Population and PD-L1 Subgroups. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 100(5), 1317. -
Safety Evaluation of Nivolumab Concomitant With Platinum-Based Chemoradiation therapy for Intermediate and High-Risk Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Foundation 3504
Gillison, M., Ferris, R. L., Zhang, Q., Colevas, A. D., Mell, L. K., Kirsch, C., … Le, Q. T. (2018). Safety Evaluation of Nivolumab Concomitant With Platinum-Based Chemoradiation therapy for Intermediate and High-Risk Local-Regionally Advanced Head and Neck Squamous Cell Carcinoma: RTOG Foundation 3504. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 100(5), 1307–8. -
Nivolumab (Nivo) vs Investigator's Choice (IC) for Platinum-Refractory (PR) Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN; CheckMate 141): Outcomes in First-line (1L) R/M Patients (Pts) and Updated Safety and Efficacy
Kasper, S., Gillison, M. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., … Ferris, R. L. (2018). Nivolumab (Nivo) vs Investigator's Choice (IC) for Platinum-Refractory (PR) Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN; CheckMate 141): Outcomes in First-line (1L) R/M Patients (Pts) and Updated Safety and Efficacy. ONCOLOGY RESEARCH AND TREATMENT, 41, 96. -
Nivolumab vs investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression
Ferris, R. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Gillison, M. L. (2018). Nivolumab vs investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck: 2-year long-term survival update of CheckMate 141 with analyses by tumor PD-L1 expression. ORAL ONCOLOGY, 81, 45–51. -
Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence.
Gao, R. W., Teraphongphom, N. T., van den Berg, N. S., Martin, B. A., Oberhelman, N. J., Divi, V., … Rosenthal, E. L. (2018). Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence. Cancer Research. -
Review of pathologic diagnosis in head and neck cancer patients: Why do it?
Zhu, G. A., Lira, R. R., & Colevas, A. D. (2014). Review of pathologic diagnosis in head and neck cancer patients: Why do it? JOURNAL OF CLINICAL ONCOLOGY, 32(15). -
Safety, pharmacokinetics (PK), and pharmacodynamics (PD) of HGS1029, an inhibitor of apoptosis protein (IAP) inhibitor, in patients (Pts) with advanced solid tumors: Results of a phase I study.
Sikic, B. I., Eckhardt, S. G., Gallant, G., Burris, H. A., Camidge, D. R., Colevas, A. D., … Infante, J. R. (2011). Safety, pharmacokinetics (PK), and pharmacodynamics (PD) of HGS1029, an inhibitor of apoptosis protein (IAP) inhibitor, in patients (Pts) with advanced solid tumors: Results of a phase I study. JOURNAL OF CLINICAL ONCOLOGY, 29(15). -
A POOLED ANALYSIS OF ADVANCED NONSQUAMOUS NSCLC PATIENTS WITH STABLE TREATED BRAIN METASTASES IN TWO PHASE II TRIALS RECEIVING BEVACIZUMAB AND PEMETREXED AS SECOND-LINE THERAPY
Gubens, M., Akerley, W., Lynch, T., Langer, C. J., Socinski, M. A., Colevas, A. D., … Wakelee, H. (2011). A POOLED ANALYSIS OF ADVANCED NONSQUAMOUS NSCLC PATIENTS WITH STABLE TREATED BRAIN METASTASES IN TWO PHASE II TRIALS RECEIVING BEVACIZUMAB AND PEMETREXED AS SECOND-LINE THERAPY. JOURNAL OF THORACIC ONCOLOGY, 6(6), S1224–S1225. -
Phase I study evaluating the safety, tolerability, and pharmacokinetics (PK) of HGS1029, a small-molecule inhibitor of apoptosis protein (IAP), in patients (pts) with advanced solid tumors.
Eckhardt, S. G., Gallant, G., Sikic, B. I., Camidge, D. R., Burris, H. A., Wakelee, H. A., … Infante, J. R. (2010). Phase I study evaluating the safety, tolerability, and pharmacokinetics (PK) of HGS1029, a small-molecule inhibitor of apoptosis protein (IAP), in patients (pts) with advanced solid tumors. JOURNAL OF CLINICAL ONCOLOGY, 28(15). -
NCCN Guidelines (R) Insights Head and Neck Cancers, Version 2.2017
Adelstein, D., Gillison, M. L., Pfister, D. G., Spencer, S., Adkins, D., Brizel, D. M., … Darlow, S. D. (2017). NCCN Guidelines (R) Insights Head and Neck Cancers, Version 2.2017. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 15(6), 761–70. -
PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma.
Amoils, M., Kim, J., Lee, C., Sunwoo, J. B., Colevas, A. D., Aasi, S. Z., … Divi, A. V. (2018). PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599818788057. -
BRAF inhibitor therapy of primary ameloblastoma
Tan, S., Pollack, J. R., Kaplan, M. J., Colevas, A. D., & West, R. B. (2016). BRAF inhibitor therapy of primary ameloblastoma. ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY, 122(4), 518–19. -
Weekly Docetaxel, Cisplatin, and Cetuximab in Palliative Treatment of Patients with Squamous Cell Carcinoma of the Head and Neck
Trieu, V., Pinto, H., Riess, J. W., Lira, R., Luciano, R., Coty, J., … Colevas, A. D. (2018). Weekly Docetaxel, Cisplatin, and Cetuximab in Palliative Treatment of Patients with Squamous Cell Carcinoma of the Head and Neck. ONCOLOGIST, 23(7), 764-+. -
A case of combination PD-1 inhibitor and intralesional 5-fluorouracil for high-frequency nonmelanoma skin cancers in an immunocompromised patient
Duy Tran, Lee, C., Colevas, A. D., & Chang, A. L. (2018). A case of combination PD-1 inhibitor and intralesional 5-fluorouracil for high-frequency nonmelanoma skin cancers in an immunocompromised patient. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY. MOSBY-ELSEVIER. -
Survival benefit of post-operative chemotherapy for intermediate-risk advanced stage head and neck cancer differs with patient age
Chen, M. M., Colevas, A. D., Megwalu, U., & Divi, V. (2018). Survival benefit of post-operative chemotherapy for intermediate-risk advanced stage head and neck cancer differs with patient age. ORAL ONCOLOGY, 84, 71–75. -
Pembrolizumab for advanced basal cell carcinoma: an investigator-initiated, proof-of-concept study.
Chang, A. L., Tran, D. C., Cannon, J. G., Li, S., Jeng, M., Patel, R., … Colevas, A. D. (2018). Pembrolizumab for advanced basal cell carcinoma: an investigator-initiated, proof-of-concept study. Journal of the American Academy of Dermatology. -
Safety and Clinical Activity of Atezolizumab in Head and Neck Cancer: Results From a Phase I Trial.
Colevas, A. D., Bahleda, R., Braiteh, F., Balmanoukian, A., Brana, I., Chau, N. G., … Powderly, J. (2018). Safety and Clinical Activity of Atezolizumab in Head and Neck Cancer: Results From a Phase I Trial. Annals of Oncology : Official Journal of the European Society for Medical Oncology. -
CheckMate 141: 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer
Gillison, M. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Ferris, R. L. (2018). CheckMate 141: 1-Year Update and Subgroup Analysis of Nivolumab as First-Line Therapy in Patients with Recurrent/Metastatic Head and Neck Cancer. ONCOLOGIST, 23(9), 1079–82. -
Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis.
Xiang, M., Holsinger, F. C., Colevas, A. D., Chen, M. M., Le, Q.-T., & Beadle, B. M. (2018). Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis. Cancer. -
Outcomes of elderly patients treated for oral cavity squamous cell carcinoma
Shah, J. L., Kaplan, M., Colevas, A. D., Quynh-Thu Le, & Hara, W. (2015). Outcomes of elderly patients treated for oral cavity squamous cell carcinoma. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Low pre-operative absolute monocyte count to predict overall survival benefit for oral cavity squamous cell carcinoma
Bui, T., Shah, J. L., Kaplan, M., Colevas, A. D., Quynh-Thu Le, & Hara, W. (2015). Low pre-operative absolute monocyte count to predict overall survival benefit for oral cavity squamous cell carcinoma. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy.
Chen, Y.-P., Wang, Y.-Q., Lv, J.-W., Li, Y.-Q., Chua, M. L., Le, Q.-T., … Ma, J. (2018). Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy. Annals of Oncology : Official Journal of the European Society for Medical Oncology. -
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.
Gillison, M. L., Trotti, A. M., Harris, J., Eisbruch, A., Harari, P. M., Adelstein, D. J., … Le, Q. T. (2018). Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial. Lancet (London, England). -
Cisplatin or Carboplatin-Based Chemoradiation for Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck: A Population-Based Comparison
Xiang, M., Holsinger, F. C., Colevas, A. D., Hara, W., Le, Q. T., & Beadle, B. M. (2018). Cisplatin or Carboplatin-Based Chemoradiation for Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck: A Population-Based Comparison. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 102(3), E371. -
Cost comparison of treatment for oropharyngeal carcinoma.
Tam, K., Orosco, R. K., Dimitrios Colevas, A., Bedi, N., Starmer, H. M., Beadle, B. M., & Christopher Holsinger, F. (2018). Cost comparison of treatment for oropharyngeal carcinoma. The Laryngoscope. -
NRG-RTOG 1016: Phase III Trial Comparing Radiation/Cetuximab to Radiation/Cisplatin in HPV-related Cancer of the Oropharynx
Trotti, A., Harris, J., Gillison, M., Eisbruch, A., Harari, P. M., Adelstein, D. J., … Le, Q. T. (2018). NRG-RTOG 1016: Phase III Trial Comparing Radiation/Cetuximab to Radiation/Cisplatin in HPV-related Cancer of the Oropharynx. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 102(5), 1604–5. -
Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma.
van Keulen, S., van den Berg, N. S., Nishio, N., Birkeland, A., Zhou, Q., Lu, G., … Rosenthal, E. L. (2019). Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma. Oral Oncology, 88, 58–65. -
The Clinical Application of Fluorescence-Guided Surgery in Head and Neck Cancer.
van Keulen, S., Nishio, N., Fakurnejad, S., Birkeland, A., Martin, B. A., Lu, G., … Rosenthal, E. L. (2019). The Clinical Application of Fluorescence-Guided Surgery in Head and Neck Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. -
First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers.
Sikic, B. I., Lakhani, N., Patnaik, A., Shah, S. A., Chandana, S. R., Rasco, D., … Padda, S. K. (2019). First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO1802018. -
Hearing evaluation of head and neck cancer patients (HNCP): Comparison of adverse event (AE) criteria
Colevas, A. D., Lira, R. R., Colevas, E. A., Lavori, P. W., & Chang, K. W. (2012). Hearing evaluation of head and neck cancer patients (HNCP): Comparison of adverse event (AE) criteria. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
High incidence of larynx cancers in Vietnamese population in the bay area
Huang, D. D., Filion, E. J., Chang, E., Colevas, A. D., Kaplan, M. J., & Le, Q. (2008). High incidence of larynx cancers in Vietnamese population in the bay area. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72(1), S484. -
A phase 2 trial of flavopiridol and cisplatin in platinum-resistant ovarian cancer
Peethambaram, P. P., Burton, J. K., Oberg, A. L., Gomez-Dahl, L. C., Isham, C. R., Tibodeau, J. D., … Bible, K. C. (2007). A phase 2 trial of flavopiridol and cisplatin in platinum-resistant ovarian cancer. MOLECULAR CANCER THERAPEUTICS. AMER ASSOC CANCER RESEARCH. -
Nivolumab vs Investigator'S Choice (IC) in Patients With Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN): Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use
Ferris, R. L., Licitra, L., Fayette, J., Even, C., Blumenschein, G., Harrington, K. J., … Gillison, M. L. (2017). Nivolumab vs Investigator'S Choice (IC) in Patients With Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN): Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY. WILEY. -
Nivolumab Versus Investigator'S Choice (IC) for Platinum-Refractory Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN; CHECKMATE 141): Outcomes in First-Line R/M Patients and Updated Safety and Efficacy
Gillison, M. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Ferris, R. L. (2017). Nivolumab Versus Investigator'S Choice (IC) for Platinum-Refractory Recurrent or Metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN; CHECKMATE 141): Outcomes in First-Line R/M Patients and Updated Safety and Efficacy. ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 13, 144. -
Characterisation of Potential Predictive Biomarkers of Response to Nivolumab in Checkmate 141 in Patients With Squamous Cell Carcinoma of the Head and Neck (SCCHN)
Concha-Benavente, F., Gillison, M. L., Blumenschien, G., Harrington, K. J., Fayette, J., Colevas, A. D., … Ferris, R. L. (2017). Characterisation of Potential Predictive Biomarkers of Response to Nivolumab in Checkmate 141 in Patients With Squamous Cell Carcinoma of the Head and Neck (SCCHN). ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY, 13, 141. -
Treatment beyond progression with nivolumab in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) in the phase 3 checkmate 141 study: A biomarker analysis and updated clinical outcomes
Haddad, R., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Ferris, R. L. (2017). Treatment beyond progression with nivolumab in patients with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) in the phase 3 checkmate 141 study: A biomarker analysis and updated clinical outcomes. ANNALS OF ONCOLOGY, 28. -
Long-Term Safety and Clinical Outcomes of Atezolizumab in Head and Neck Cancer: Phase la Trial Results
Bahleda, R., Braiteh, F. S., Balmanoukian, A. S., Brana, I., Hodi, F. S., Garbo, L., … Colevas, A. D. (2017). Long-Term Safety and Clinical Outcomes of Atezolizumab in Head and Neck Cancer: Phase la Trial Results. ANNALS OF ONCOLOGY, 28. -
Treatment beyond progression with nivolumab (nivo) in patients with recurrent or metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the phase 3 CheckMate 141 study
Kasper, S., Haddad, R., Ferris, R. L., Blumenschein, G., Fayette, J., Guigay, J., … Harrington, K. J. (2017). Treatment beyond progression with nivolumab (nivo) in patients with recurrent or metastatic (R/M) Squamous Cell Carcinoma of the Head and Neck (SCCHN) in the phase 3 CheckMate 141 study. ONCOLOGY RESEARCH AND TREATMENT, 40, 250-+. -
Commentary on "Weekly Low-Dose Versus Three-Weekly High-Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non-Nasopharyngeal Head and Neck Cancer: A Systematic Review and Meta-Analysis of Aggregate Data"
Colevas, A. D. (2017). Commentary on "Weekly Low-Dose Versus Three-Weekly High-Dose Cisplatin for Concurrent Chemoradiation in Locoregionally Advanced Non-Nasopharyngeal Head and Neck Cancer: A Systematic Review and Meta-Analysis of Aggregate Data". ONCOLOGIST, 22(9), 1022–23. -
Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial
Harrington, K. J., Ferris, R. L., Blumenschein, G., Colevas, A. D., Fayette, J., Licitra, L., … Guigay, J. (2017). Nivolumab versus standard, single-agent therapy of investigator's choice in recurrent or metastatic squamous cell carcinoma of the head and neck (CheckMate 141): health-related quality-of-life results from a randomised, phase 3 trial. LANCET ONCOLOGY, 18(8), 1104–15. -
PD-1 inhibition for cutaneous squamous cell carcinoma: A study of six consecutive cases
Duy Tran, Colevas, A. D., & Chang, A. (2017). PD-1 inhibition for cutaneous squamous cell carcinoma: A study of six consecutive cases. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 76(6), AB193. -
Outcomes of Young Patients With Oral Cavity Squamous Cell Carcinoma
Shah, J. L., Bui, T., Kaplan, M., Colevas, A. D., Le, Q. T., & Hara, W. (2015). Outcomes of Young Patients With Oral Cavity Squamous Cell Carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 93(3), S214. -
Prognostic Value of Lymph Node Status Is Greater Than Lymph Node Ratio and AJCC N Staging for Head and Neck Squamous Cell Carcinomas
Roberts, T., Colevas, A. D., Hara, W., Holsinger, F. C., Oakley-Girvan, I., & Divi, V. (2016). Prognostic Value of Lymph Node Status Is Greater Than Lymph Node Ratio and AJCC N Staging for Head and Neck Squamous Cell Carcinomas. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
A Case Report of Unresectable Cutaneous Squamous Cell Carcinoma Responsive to Pembrolizumab, a Programmed Cell Death Protein 1 Inhibitor
Chang, A. L. S., Kim, J., Luciano, R., Sullivan-Chang, L., & Colevas, A. D. (2016). A Case Report of Unresectable Cutaneous Squamous Cell Carcinoma Responsive to Pembrolizumab, a Programmed Cell Death Protein 1 Inhibitor. JAMA DERMATOLOGY, 152(1), 106–8. -
New Diseases and New Treatments-Head and Neck Cancer Updates Preface
Colevas, A. D. (2015). New Diseases and New Treatments-Head and Neck Cancer Updates Preface. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 29(6), XIII-XIV. -
E1308: Reduced-dose IMRT in human papilloma virus (HPV)-associated resectable oropharyngeal squamous carcinomas (OPSCC) after clinical complete response (cCR) to induction chemotherapy (IC).
Cmelak, A., Li, S., Marur, S., Zhao, W., Westra, W. H., Chung, C. H., … Burtriess, B. (2014). E1308: Reduced-dose IMRT in human papilloma virus (HPV)-associated resectable oropharyngeal squamous carcinomas (OPSCC) after clinical complete response (cCR) to induction chemotherapy (IC). JOURNAL OF CLINICAL ONCOLOGY, 32(18). -
E1308: Reduced-dose INERT in human papilloma virus (HPV)-associated resectable oropharyngeal squamous carcinomas (OPSCC) after clinical complete response (cCR) to induction chemotherapy (IC).
Cmelak, A., Li, S., Marur, S., Zhao, W., Westra, W. H., Chung, C. H., … Burtness, B. (2014). E1308: Reduced-dose INERT in human papilloma virus (HPV)-associated resectable oropharyngeal squamous carcinomas (OPSCC) after clinical complete response (cCR) to induction chemotherapy (IC). JOURNAL OF CLINICAL ONCOLOGY, 32(15). -
Third party assessment of resection margin status in head and neck cancer.
Ransohoff, A., Wood, D., Henry, S., Divi, V., & Colevas, A. D. (2015). Third party assessment of resection margin status in head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Evaluation of patients with disseminated or locoregionally advanced thyroid cancer: a primer for medical oncologists.
Colevas, A. D., & Shah, M. H. (2012). Evaluation of patients with disseminated or locoregionally advanced thyroid cancer: a primer for medical oncologists. American Society of Clinical Oncology Educational Book. American Society of Clinical Oncology. Annual Meeting, 384–88. -
E 1308: A phase II trial of induction chemotherapy (IC) followed by cetuximab with low dose versus standard dose IMRT in patients with human papilloma virus (HPV)-associated resectable squamous cell carcinoma of the oropharynx (OPSCC)
Marur, S., Li, S., Cmelak, A., Gillison, M. L., Ferris, R. L., Bauman, J. E., … Colevas, A. D. (2013). E 1308: A phase II trial of induction chemotherapy (IC) followed by cetuximab with low dose versus standard dose IMRT in patients with human papilloma virus (HPV)-associated resectable squamous cell carcinoma of the oropharynx (OPSCC). JOURNAL OF CLINICAL ONCOLOGY, 31(15). -
Chemoradiation for nasopharyngeal carcinoma (NPC) with pilot hypoxia imaging with F18 misonidazole PET scanning.
Colevas, A. D., Quon, A., McMillan, A., & Le, Q. (2011). Chemoradiation for nasopharyngeal carcinoma (NPC) with pilot hypoxia imaging with F18 misonidazole PET scanning. JOURNAL OF CLINICAL ONCOLOGY, 29(15). -
A population-based evaluation of incidence trends in oropharynx cancer (OP) focusing on socioeconomic status (SES), sex, and race/ethnicity
Colevas, A. D., Clarke, C. A., Lichtensztajn, D., & Chang, E. T. (2010). A population-based evaluation of incidence trends in oropharynx cancer (OP) focusing on socioeconomic status (SES), sex, and race/ethnicity. JOURNAL OF CLINICAL ONCOLOGY, 28(15). -
Plasma human papillomavirus (HPV) DNA as a potential tool for tumor detection and monitoring response in HPV-related oropharyngeal carcinoma (OP)
Cao, H., Kwok, S., Shi, X., Bala, R., Pinsky, B., Colevas, A. D., … Le, Q. (2010). Plasma human papillomavirus (HPV) DNA as a potential tool for tumor detection and monitoring response in HPV-related oropharyngeal carcinoma (OP). JOURNAL OF CLINICAL ONCOLOGY, 28(15). -
Nano-immunoassay profiling of ERK and MEK isoforms in fine-needle aspirates of solid tumors
Fan, A. C., Dermody, J., Kong, C., Zhang, N., Colevas, A. D., & Felsher, D. W. (2010). Nano-immunoassay profiling of ERK and MEK isoforms in fine-needle aspirates of solid tumors. JOURNAL OF CLINICAL ONCOLOGY, 28(15). -
A phase I study of an oral formulation of ixabepilone (ixa) in patients with advanced cancer
He, A. R., Kunz, P. L., Pishvaian, M. J., Colevas, A. D., Hwang, J. J., Clemens, P. L., … Sikic, B. I. (2010). A phase I study of an oral formulation of ixabepilone (ixa) in patients with advanced cancer. JOURNAL OF CLINICAL ONCOLOGY, 28(15). -
Toxicity Monitoring: Why, What, When.?
Colevas, A. D. (2010). Toxicity Monitoring: Why, What, When.? ONCOLOGY CLINICAL TRIALS, 151–61. -
Intensity Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure
Wiegner, E. A., Daly, M. E., Chapman, C. H., Yu, Y., Colevas, A. D., Kaplan, M. J., … Chang, D. T. (2010). Intensity Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S463. -
Phase I Trial of Bortezomib (NSC 681239) and Flavopiridol (NSC 649890) in Patients with Recurrent or Refractory Indolent B-Cell Neoplasms
Grant, S., Sullivan, D., Roodman, D., Stuart, R. K., Perkins, E., Kolla, S., … Roberts, J. D. (2008). Phase I Trial of Bortezomib (NSC 681239) and Flavopiridol (NSC 649890) in Patients with Recurrent or Refractory Indolent B-Cell Neoplasms. BLOOD. AMER SOC HEMATOLOGY. -
Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy.
Thu Le, Q., Dimitrios Colevas, A., O'Sullivan, B., Lee, A. W., Lee, N., Ma, B., … Malik, S. (2019). Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy. Journal of the National Cancer Institute. -
Discordance in routine second opinion pathology review of head and neck oncology specimens: A single-center five year retrospective review.
Zhu, G. A., Lira, R., & Colevas, A. D. (2016). Discordance in routine second opinion pathology review of head and neck oncology specimens: A single-center five year retrospective review. Oral Oncology, 53, 36–41. -
Balancing Safety and Efficacy of Epidermal Growth Factor Receptor Inhibitors in Patients With Squamous Cell Carcinoma of the Head and Neck.
Iberri, D. J., & Colevas, A. D. (2015). Balancing Safety and Efficacy of Epidermal Growth Factor Receptor Inhibitors in Patients With Squamous Cell Carcinoma of the Head and Neck. The Oncologist. -
PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma
Amoils, M., Kim, J., Lee, C., Sunwoo, J. B., Colevas, A. D., Aasi, S. Z., … Divi, V. (2019). PD-L1 Expression and Tumor-Infiltrating Lymphocytes in High-Risk and Metastatic Cutaneous Squamous Cell Carcinoma. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 160(1), 93–99. -
Optimal Dosing Strategy for Fluorescence-Guided Surgery with Panitumumab-IRDye800CW in Head and Neck Cancer.
Nishio, N., van den Berg, N. S., van Keulen, S., Martin, B. A., Fakurnejad, S., Zhou, Q., … Rosenthal, E. L. (2019). Optimal Dosing Strategy for Fluorescence-Guided Surgery with Panitumumab-IRDye800CW in Head and Neck Cancer. Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging. -
Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence
Gao, R. W., Teraphongphom, N. T., van den Berg, N. S., Martin, B. A., Oberhelman, N. J., Divi, V., … Rosenthal, E. L. (2018). Determination of Tumor Margins with Surgical Specimen Mapping Using Near-Infrared Fluorescence. CANCER RESEARCH, 78(17), 5144–54. -
Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis
Xiang, M., Holsinger, F. C., Colevas, A. D., Chen, M. M., Quynh-Thu Le, & Beadle, B. M. (2018). Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis. CANCER, 124(23), 4486–94. -
First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers
Sikic, B., Lakhani, N., Patnaik, A., Shah, S. A., Chandana, S. R., Rasco, D., … Padda, S. K. (2019). First-in-Human, First-in-Class Phase I Trial of the Anti-CD47 Antibody Hu5F9-G4 in Patients With Advanced Cancers. JOURNAL OF CLINICAL ONCOLOGY, 37(12), 946-+. -
Pembrolizumab with or without vismodegib for advanced basal cell carcinoma: An investigator-initiated, proof-of-concept study
Chang, A., Tran, D. C., Cannon, J., Li, S., Jeng, M., Rieger, K., … Colevas, A. (2019). Pembrolizumab with or without vismodegib for advanced basal cell carcinoma: An investigator-initiated, proof-of-concept study. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 139(5), S92. -
Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma
van Keulen, S., van den Berg, N. S., Nishio, N., Birkeland, A., Zhou, Q., Lu, G., … Rosenthal, E. L. (2019). Rapid, non-invasive fluorescence margin assessment: Optical specimen mapping in oral squamous cell carcinoma. ORAL ONCOLOGY, 88, 58–65. -
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial
Gillison, M. L., Trotti, A. M., Harris, J., Eisbruch, A., Harari, P. M., Adelstein, D. J., … Quynh Thu Le. (2019). Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial. LANCET, 393(10166), 40–50. -
Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy
Chen, Y.-P., Wang, Y.-Q., Lv, J.-W., Li, Y.-Q., Chua, M. L. K., Le, Q.-T., … Ma, J. (2019). Identification and validation of novel microenvironment-based immune molecular subgroups of head and neck squamous cell carcinoma: implications for immunotherapy. ANNALS OF ONCOLOGY, 30(1), 68–75. -
Characterization of potential predictive biomarkers of response to nivolumab in CheckMate-141 in patients with squamous cell carcinoma of the head and neck (SCCHN).
Ferris, R. L., Concha-Benavente, F., Blumenschein, G. R., Harrington, K. J., Fayette, J., Colevas, A. D., … Vokes, E. E. (2017). Characterization of potential predictive biomarkers of response to nivolumab in CheckMate-141 in patients with squamous cell carcinoma of the head and neck (SCCHN). JOURNAL OF CLINICAL ONCOLOGY, 35(7). -
Pembrolizumab for advanced basal cell carcinoma: An investigator-initiated, proof-of-concept study
Chang, A. L. S., Tran, D. C., Cannon, J. G. D., Li, S., Jeng, M., Patel, R., … Colevas, A. D. (2019). Pembrolizumab for advanced basal cell carcinoma: An investigator-initiated, proof-of-concept study. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 80(2), 564–66. -
A randomized phase II study of chemoradiation (CRT) plus /- nivolumab (Nivo) with sequential safety evaluations of Nivo plus /- lirilumab (Liri) or ipilumumab (Ipi) concomitant with (C) RI in intermediate (IR) and high-risk (HR) head and neck squamous cell carcinoma (HNSCC) (RTOG 3504, NCT02764593).
Gillison, M. L., Ferris, R. L., Zhang, Q., Colevas, A. D., Mell, L. K., Kong, C., … Le, Q.-T. (2017). A randomized phase II study of chemoradiation (CRT) plus /- nivolumab (Nivo) with sequential safety evaluations of Nivo plus /- lirilumab (Liri) or ipilumumab (Ipi) concomitant with (C) RI in intermediate (IR) and high-risk (HR) head and neck squamous cell carcinoma (HNSCC) (RTOG 3504, NCT02764593). JOURNAL OF CLINICAL ONCOLOGY, 35. -
The Sentinel Margin: Intraoperative ex-vivo Specimen Mapping Using Relative Fluorescence Intensity.
van Keulen, S., Nishio, N., Birkeland, A., Fakurnejad, S., Martin, B. A., Forouzanfar, T., … Rosenthal, E. L. (2019). The Sentinel Margin: Intraoperative ex-vivo Specimen Mapping Using Relative Fluorescence Intensity. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Nivolumab (Nivo) vs investigator's choice (IC) in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): 2-yr outcomes in the overall population and PD-L1 subgroups of CheckMate 141
Ferris, R. L., Blumenschein, G. R., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Gillison, M. L. (2018). Nivolumab (Nivo) vs investigator's choice (IC) in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): 2-yr outcomes in the overall population and PD-L1 subgroups of CheckMate 141. CANCER RESEARCH, 78(13). -
The Clinical Application of Fluorescence-Guided Surgery in Head and Neck Cancer
van Keulen, S., Nishio, N., Fakurnejad, S., Birkeland, A., Martin, B. A., Lu, G., … Rosenthal, E. L. (2019). The Clinical Application of Fluorescence-Guided Surgery in Head and Neck Cancer. JOURNAL OF NUCLEAR MEDICINE, 60(6), 758–63. -
An open-label, single-arm, multi-institutional phase II trial of avelumab for recurrent, metastatic nasopharyngeal carcinoma.
Sacco, A. G., Messer, K., Leidner, R. S., Colevas, A. D., Nieva, J. J., Chau, N. G., … Cohen, E. E. W. (2017). An open-label, single-arm, multi-institutional phase II trial of avelumab for recurrent, metastatic nasopharyngeal carcinoma. JOURNAL OF CLINICAL ONCOLOGY, 35. -
Characterization of potential predictive biomarkers of response to nivolumab in CheckMate 141 in patients with squamous cell carcinoma of the head and neck (SCCHN).
Concha-Benavente, F., Gillison, M. L., Blumenschein, G. R., Harrington, K., Fayette, J., Colevas, A. D., … Ferris, R. L. (2017). Characterization of potential predictive biomarkers of response to nivolumab in CheckMate 141 in patients with squamous cell carcinoma of the head and neck (SCCHN). JOURNAL OF CLINICAL ONCOLOGY, 35. -
Further evaluations of nivolumab (nivo) versus investigator's choice (IC) chemotherapy for recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): CheckMate 141.
Ferris, R. L., Blumenschein, G. R., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L. F., … Gillison, M. L. (2016). Further evaluations of nivolumab (nivo) versus investigator's choice (IC) chemotherapy for recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): CheckMate 141. JOURNAL OF CLINICAL ONCOLOGY, 34(15). -
Nivolumab treatment beyond RECIST-defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141: A subgroup analysis of a randomized phase 3 clinical trial.
Haddad, R., Concha-Benavente, F., Blumenschein, G. J., Fayette, J., Guigay, J., Colevas, A. D., … Ferris, R. L. (2019). Nivolumab treatment beyond RECIST-defined progression in recurrent or metastatic squamous cell carcinoma of the head and neck in CheckMate 141: A subgroup analysis of a randomized phase 3 clinical trial. Cancer. -
Nivolumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use.
Ferris, R. L., Licitra, L., Fayette, J., Even, C., Blumenschein, G. R., Harrington, K. J., … Gillison, M. L. (2019). Nivolumab in Patients With Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck: Efficacy and Safety in CheckMate 141 by Prior Cetuximab Use. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Development and validation of radiomic signatures of head and neck squamous cell carcinoma molecular features and subtypes.
Huang, C., Cintra, M., Brennan, K., Zhou, M., Colevas, A. D., Fischbein, N., … Gevaert, O. (2019). Development and validation of radiomic signatures of head and neck squamous cell carcinoma molecular features and subtypes. EBioMedicine. -
Cost comparison of treatment for oropharyngeal carcinoma
Tam, K., Orosco, R. K., Colevas, A. D., Bedi, N., Starmer, H. M., Beadle, B. M., & Holsinger, F. C. (2019). Cost comparison of treatment for oropharyngeal carcinoma. LARYNGOSCOPE, 129(7), 1604–9. -
A first-in-human, first-in-class phase I trial of the anti-CD47 antibody Hu5F9-G4 in patients with advanced cancers
Sikic, B. I., Lakhani, N., Patnaik, A., Shah, S. A., Chandana, S. R., Rasco, D., … Padda, S. K. (2016). A first-in-human, first-in-class phase I trial of the anti-CD47 antibody Hu5F9-G4 in patients with advanced cancers. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
A phase 2 study of tarloxotinib bromide (TRLX) in patients (Pts) with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) or skin (SCCS).
Rischin, D., Boyer, M. J., Brzezniak, C. E., Colevas, A. D., Doebele, R. C., Gilbert, J., … Liu, S. V. (2016). A phase 2 study of tarloxotinib bromide (TRLX) in patients (Pts) with recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN) or skin (SCCS). JOURNAL OF CLINICAL ONCOLOGY, 34(15). -
Fluorescence molecular imaging for identification of high-grade dysplasia in patients with head and neck cancer.
Fakurnejad, S., van Keulen, S., Nishio, N., Engelen, M., van den Berg, N. S., Lu, G., … Martin, B. A. (2019). Fluorescence molecular imaging for identification of high-grade dysplasia in patients with head and neck cancer. Oral Oncology, 97, 50–55. -
Survival After Definitive Chemoradiotherapy With Concurrent Cisplatin or Carboplatin for Head and Neck Cancer.
Xiang, M., Colevas, A. D., Holsinger, F. C., Le, Q.-T. X., & Beadle, B. M. (2019). Survival After Definitive Chemoradiotherapy With Concurrent Cisplatin or Carboplatin for Head and Neck Cancer. Journal of the National Comprehensive Cancer Network : JNCCN, 17(9), 1065–73. -
Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy
Le, Q. T., Colevas, A. D., OSullivan, B., Lee, A. W. M., Lee, N., Ma, B., … Malik, S. (2019). Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 111(7), 655–63. -
Intraoperative Tumor Assessment Using Real-Time Molecular Imaging in Head and Neck Cancer Patients.
Keulen, S. van, Nishio, N., Fakurnejad, S., van den Berg, N. S., Lu, G., Birkeland, A., … Rosenthal, E. L. (2019). Intraoperative Tumor Assessment Using Real-Time Molecular Imaging in Head and Neck Cancer Patients. Journal of the American College of Surgeons. -
Probe-based fluorescence dosimetry of an antibody-dye conjugate to identify head and neck cancer as a first step to fluorescence-guided tissue preselection for pathological assessment.
Nishio, N., van Keulen, S., van den Berg, N. S., Lu, G., LaRochelle, E. P., Davis, S. C., … Rosenthal, E. L. (2019). Probe-based fluorescence dosimetry of an antibody-dye conjugate to identify head and neck cancer as a first step to fluorescence-guided tissue preselection for pathological assessment. Head & Neck. -
Safety and disease control achieved with the addition of nivolumab (Nivo) to chemoradiotherapy (CRT) for intermediate (IR) and high-risk (HR) local-regionally advanced head and neck squamous cell carcinoma (HNSCC): RTOG Foundation 3504.
Gillison, M. L., Ferris, R. L., Harris, J., Colevas, A. D., Mell, L. K., Kong, C., … Quynh-Thu Le. (2019). Safety and disease control achieved with the addition of nivolumab (Nivo) to chemoradiotherapy (CRT) for intermediate (IR) and high-risk (HR) local-regionally advanced head and neck squamous cell carcinoma (HNSCC): RTOG Foundation 3504. JOURNAL OF CLINICAL ONCOLOGY, 37(15). -
Tabelecleucel in combination with pembrolizumab (Pembro) in platinum-pretreated, recurrent/metastatic Epstein-Barr virus (EBV)-positive nasopharyngeal carcinoma (EBV plus NPC).
Siu, L. L., Bauml, J., Adkins, D., Colevas, A. D., Perez, C. A., Choe, J. H., … Pfister, D. G. (2019). Tabelecleucel in combination with pembrolizumab (Pembro) in platinum-pretreated, recurrent/metastatic Epstein-Barr virus (EBV)-positive nasopharyngeal carcinoma (EBV plus NPC). JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Assessing Care Value for Older Patients Receiving Radiotherapy With or Without Cisplatin or Cetuximab for Locoregionally Advanced Head and Neck Cancer.
Saraswathula, A., Chen, M. M., Colevas, A. D., & Divi, V. (2019). Assessing Care Value for Older Patients Receiving Radiotherapy With or Without Cisplatin or Cetuximab for Locoregionally Advanced Head and Neck Cancer. JAMA Otolaryngology-- Head & Neck Surgery. -
Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer.
Nishio, N., van den Berg, N. S., van Keulen, S., Martin, B. A., Fakurnejad, S., Teraphongphom, N., … Rosenthal, E. L. (2019). Optical molecular imaging can differentiate metastatic from benign lymph nodes in head and neck cancer. Nature Communications, 10(1), 5044. -
Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.
Nambiar, D. K., Aguilera, T., Cao, H., Kwok, S., Kong, C., Bloomstein, J., … Le, Q. T. (2019). Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. The Journal of Clinical Investigation. -
Predicting Therapeutic Antibody Delivery into Human Head and Neck Cancers.
Lu, G., Fakurnejad, S., Martin, B. A., van den Berg, N. S., van Keulen, S., Nishio, N., … Rosenthal, E. L. (2020). Predicting Therapeutic Antibody Delivery into Human Head and Neck Cancers. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Intraoperative Molecular Imaging for ex vivo Assessment of Peripheral Margins in Oral Squamous Cell Carcinoma.
Fakurnejad, S., Krishnan, G., van Keulen, S., Nishio, N., Birkeland, A. C., Baik, F. M., … Martin, B. A. (2019). Intraoperative Molecular Imaging for ex vivo Assessment of Peripheral Margins in Oral Squamous Cell Carcinoma. Frontiers in Oncology, 9, 1476. -
Optimal Dosing Strategy for Fluorescence-Guided Surgery with Panitumumab-IRDye800CW in Head and Neck Cancer
Nishio, N., van den Berg, N. S., van Keulen, S., Martin, B. A., Fakurnejad, S., Zhou, Q., … Rosenthal, E. L. (2020). Optimal Dosing Strategy for Fluorescence-Guided Surgery with Panitumumab-IRDye800CW in Head and Neck Cancer. MOLECULAR IMAGING AND BIOLOGY, 22(1), 156–64. -
Exome scale liquid biopsy monitoring of putative neoantigens and genomic biomarkers in patients on anti-PD-1 therapy in squamous cell carcinoma of the head and neck.
Abbott, C. W., Bedi, N., Zhang, S. V., Li, R., Pyke, R. M., Levy, E., … Boyle, S. M. (2020). Exome scale liquid biopsy monitoring of putative neoantigens and genomic biomarkers in patients on anti-PD-1 therapy in squamous cell carcinoma of the head and neck. CANCER IMMUNOLOGY RESEARCH. AMER ASSOC CANCER RESEARCH. -
A first-in-class, first-in-human phase 1 pharmacokinetic (PK) and pharmacodynamic (PD) study of Hu5F9-G4, an anti-CD47 monoclonal antibody (mAb), in patients with advanced solid tumors.
Sikic, B. I., Lakhani, N. J., Patnaik, A., Shah, S., Chandana, S. R., Rasco, D. W., … Padda, S. K. (2018). A first-in-class, first-in-human phase 1 pharmacokinetic (PK) and pharmacodynamic (PD) study of Hu5F9-G4, an anti-CD47 monoclonal antibody (mAb), in patients with advanced solid tumors. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
CT-based Radiomic Signatures for Predicting Histopathologic Features in Head and Neck Squamous Cell Carcinoma.
Mukherjee, P., Cintra, M., Huang, C., Zhou, M., Zhu, S., Colevas, A. D., … Gevaert, O. (2020). CT-based Radiomic Signatures for Predicting Histopathologic Features in Head and Neck Squamous Cell Carcinoma. Radiology. Imaging Cancer, 2(3), e190039. -
Radiotherapy plus cetuximab or cisplatin in human papilloma-virus positive oropharyngeal cancer (NRG 1016): A randomized multicenter noninferiority trial
Ridge, J. A., Ringash, J., Yao, M., Blakaj, D. M., Razaq, M. A., Colevas, A. D., … Burtness, B. (2020). Radiotherapy plus cetuximab or cisplatin in human papilloma-virus positive oropharyngeal cancer (NRG 1016): A randomized multicenter noninferiority trial. CLINICAL CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Intraoperative Fluorescence-Guided Surgery in Head and Neck Squamous Cell Carcinoma
Lee, Y.-J., Krishnan, G., Nishio, N., van den Berg, N. S., Lu, G., Martin, B. A., … Rosenthal, E. L. (2020). Intraoperative Fluorescence-Guided Surgery in Head and Neck Squamous Cell Carcinoma. LARYNGOSCOPE. -
Safety evaluation of nivolumab (Nivo) concomitant with cetuximab-radiotherapy for intermediate (IR) and high-risk (HR) local-regionally advanced head and neck squamous cell carcinoma (HNSCC): RTOG 3504.
Ferris, R. L., Gillison, M. L., Harris, J., Colevas, A. D., Mell, L. K., Kong, C., … Le, Q.-T. (2018). Safety evaluation of nivolumab (Nivo) concomitant with cetuximab-radiotherapy for intermediate (IR) and high-risk (HR) local-regionally advanced head and neck squamous cell carcinoma (HNSCC): RTOG 3504. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging.
Pei, J., Juniper, G., van den Berg, N. S., Nisho, N., Broadt, T., Welch, A. R., … Rosenthal, E. L. (2020). Safety and Stability of Antibody-Dye Conjugate in Optical Molecular Imaging. Molecular Imaging and Biology. -
Metastatic cutaneous squamous cell carcinoma responsive to cemiplimab in a patient with multiple myeloma.
Marukian, N. V., Lin, J. Q., Colevas, A. D., Coutre, S., & Chang, A. L. (2020). Metastatic cutaneous squamous cell carcinoma responsive to cemiplimab in a patient with multiple myeloma. JAAD Case Reports, 6(9), 819–21. -
Association Between Immunosuppression and Outcomes in Oral Cavity Squamous Cell Carcinoma.
Chang, J., Sunwoo, J. B., Shah, J. L., Hara, W., Hong, J., Colevas, A. D., & Divi, V. (2020). Association Between Immunosuppression and Outcomes in Oral Cavity Squamous Cell Carcinoma. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599820960146. -
Exome scale liquid biopsy characterization of putative neoantigens and genomic biomarkers pre- and post anti-PD-1 therapy in squamous cell carcinoma of the head and neck.
Abbott, C., Bedi, N., Zhang, S., Li, R., Pyke, R., Levy, E., … Boyle, S. M. (2020). Exome scale liquid biopsy characterization of putative neoantigens and genomic biomarkers pre- and post anti-PD-1 therapy in squamous cell carcinoma of the head and neck. JOURNAL OF CLINICAL ONCOLOGY. AMER SOC CLINICAL ONCOLOGY. -
Head and Neck Cancers, Version 2.2020
Pfister, D. G., Spencer, S., Adelstein, D., Adkins, D., Anzai, Y., Brizel, D. M., … Darlow, S. D. (2020). Head and Neck Cancers, Version 2.2020. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 18(7), 873–98. -
Co-administered antibody improves penetration of antibody-dye conjugate into human cancers with implications for antibody-drug conjugates.
Lu, G., Nishio, N., van den Berg, N. S., Martin, B. A., Fakurnejad, S., van Keulen, S., … Rosenthal, E. L. (2020). Co-administered antibody improves penetration of antibody-dye conjugate into human cancers with implications for antibody-drug conjugates. Nature Communications, 11(1), 5667. -
Survival Benefit of Postoperative Radiotherapy in Pathological N1 Oral Cavity Squamous Cell Carcinoma
Xiang, M., Holsinger, F. C., Gensheimer, M. F., Divi, V., Pollom, E., Colevas, A. D., … Beadle, B. M. (2020). Survival Benefit of Postoperative Radiotherapy in Pathological N1 Oral Cavity Squamous Cell Carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Treatment Breaks During Definitive Head/Neck Radiotherapy: Survival Impact and Predisposing Factors
Xiang, M., Gensheimer, M., Pollom, E., Holsinger, F. C., Colevas, A. D., Quynh-Thu Le, & Beadle, B. (2020). Treatment Breaks During Definitive Head/Neck Radiotherapy: Survival Impact and Predisposing Factors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Prolongation of definitive head and neck cancer radiotherapy: Survival impact and predisposing factors.
Xiang, M., Gensheimer, M. F., Pollom, E. L., Holsinger, F. C., Colevas, A. D., Le, Q.-T. T., & Beadle, B. M. (2020). Prolongation of definitive head and neck cancer radiotherapy: Survival impact and predisposing factors. Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. -
Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline.
Chen, Y.-P., Ismaila, N., Chua, M. L., Colevas, A. D., Haddad, R., Huang, S. H., … Ma, J. (2021). Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2003237. -
Postoperative Observation Versus Radiotherapy for Pathologic N1 Oral Cavity Squamous Cell Carcinoma.
Xiang, M., Holsinger, F. C., Gensheimer, M. F., Divi, V., Pollom, E. L., Colevas, A. D., … Beadle, B. M. (2021). Postoperative Observation Versus Radiotherapy for Pathologic N1 Oral Cavity Squamous Cell Carcinoma. American Journal of Clinical Oncology, Publish Ahead of Print. -
Unambiguous advanced radiologic extranodal extension determined by MRI predicts worse outcomes in nasopharyngeal carcinoma: Potential improvement for future editions of N category systems.
Mao, Y., Wang, S., Lydiatt, W., Shah, J. P., Colevas, A. D., Lee, A. W., … Ma, J. (2021). Unambiguous advanced radiologic extranodal extension determined by MRI predicts worse outcomes in nasopharyngeal carcinoma: Potential improvement for future editions of N category systems. Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. -
Intraoperative Fluorescence-Guided Surgery in Head and Neck Squamous Cell Carcinoma.
Lee, Y.-J. J., Krishnan, G., Nishio, N., van den Berg, N. S., Lu, G., Martin, B. A., … Rosenthal, E. L. (2021). Intraoperative Fluorescence-Guided Surgery in Head and Neck Squamous Cell Carcinoma. The Laryngoscope, 131(3), 529–534. -
Sensitive HLA loss of heterozygosity detection reveals allele-specific neoantigen expansion as resistance mechanism to anti-PD-1 therapy
Pyke, R. M., Abbott, C., Mellacheruvu, D., Zhang, S., Bedi, N., Colevas, A. D., … Boyle, S. M. (2020). Sensitive HLA loss of heterozygosity detection reveals allele-specific neoantigen expansion as resistance mechanism to anti-PD-1 therapy. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Myocarditis Surveillance with High-Sensitivity Troponin I During Cancer Treatment with Immune Checkpoint Inhibitors.
Waliany, S., Neal, J. W., Reddy, S., Wakelee, H., Shah, S. A., Srinivas, S., … Zhu, H. (2021). Myocarditis Surveillance with High-Sensitivity Troponin I During Cancer Treatment with Immune Checkpoint Inhibitors. JACC. CardioOncology, 3(1), 137–39. -
Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW
Krishnan, G., van den Berg, N. S., Nishio, N., Juniper, G., Pei, J., Zhou, Q., … Rosenthal, E. L. (2021). Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW. THERANOSTICS, 11(15), 7188–7198. -
Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW.
Krishnan, G., van den Berg, N. S., Nishio, N., Juniper, G., Pei, J., Zhou, Q., … Rosenthal, E. L. (2021). Metastatic and sentinel lymph node mapping using intravenously delivered Panitumumab-IRDye800CW. Theranostics, 11(15), 7188–7198. -
Do Steroids Matter? A Retrospective Review of Premedication for Taxane Chemotherapy and Hypersensitivity Reactions.
Lansinger, O. M., Biedermann, S., He, Z., & Colevas, A. D. (2021). Do Steroids Matter? A Retrospective Review of Premedication for Taxane Chemotherapy and Hypersensitivity Reactions. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2101200. -
Pan-cancer survey of HLA loss of heterozygosity using a robustly validated NGS-based machine learning algorithm.
Pyke, R. M., Mellacheruvu, D., Abbott, C., Dea, S., Levy, E., Zhang, S. V., … Boyle, S. M. (2021). Pan-cancer survey of HLA loss of heterozygosity using a robustly validated NGS-based machine learning algorithm. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
Longitudinal exome-scale liquid biopsy monitoring of evolving therapeutic resistance mechanisms in head and neck squamous cell carcinoma patients receiving anti-PD-1 therapy.
Abbott, C. W., Bedi, N., Zhang, S. V., Northcott, J., Li, R., Pyke, R. M., … Chen, R. (2021). Longitudinal exome-scale liquid biopsy monitoring of evolving therapeutic resistance mechanisms in head and neck squamous cell carcinoma patients receiving anti-PD-1 therapy. CANCER RESEARCH. AMER ASSOC CANCER RESEARCH. -
A randomized, controlled, open-label, phase II study of cemiplimab as a single agent and in combination with RP1 in patients with advanced cutaneous squamous cell carcinoma [CERPASS]
Haydon, A. M., Alamgeer, M., Brungs, D., Collichio, F., Khushalani, N. I., Colevas, A. D., … Hill, A. (2021). A randomized, controlled, open-label, phase II study of cemiplimab as a single agent and in combination with RP1 in patients with advanced cutaneous squamous cell carcinoma [CERPASS]. ANNALS OF ONCOLOGY. ELSEVIER. -
Post-Treatment FDG-PET/CT Hopkins Criteria Predict Locoregional Recurrence After Definitive Radiotherapy for Oropharyngeal Squamous Cell Carcinoma.
Miller, J. A., Moradi, F., Liang, R., Zhang, C., Nguyen, N., Akhtar, F., … Gensheimer, M. F. (2021). Post-Treatment FDG-PET/CT Hopkins Criteria Predict Locoregional Recurrence After Definitive Radiotherapy for Oropharyngeal Squamous Cell Carcinoma. International Journal of Radiation Oncology, Biology, Physics, 111(3S), e399. -
Genome Sequencing and Apoptotic Markers to Assess Treatment Response of Lacrimal Gland Adenoid Cystic Carcinoma to Intra-Arterial Cytoreductive Chemotherapy.
Yu, M. D., Men, C. J., Do, H., Colevas, A. D., Lin, J. H., Egbert, P. R., … Kossler, A. L. (2021). Genome Sequencing and Apoptotic Markers to Assess Treatment Response of Lacrimal Gland Adenoid Cystic Carcinoma to Intra-Arterial Cytoreductive Chemotherapy. Ophthalmic Plastic and Reconstructive Surgery. -
Post-Treatment FDG-PET/CT Hopkins Criteria Predict Locoregional Recurrence After Definitive Radiotherapy for Oropharyngeal Squamous Cell Carcinoma
Miller, J. A., Moradi, F., Liang, R., Zhang, C., Nguyen, N., Akhtar, F., … Gensheimer, M. F. (2021). Post-Treatment FDG-PET/CT Hopkins Criteria Predict Locoregional Recurrence After Definitive Radiotherapy for Oropharyngeal Squamous Cell Carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Association of HLA loss of heterozygosity with allele-specific neoantigen expansion in response to immunotherapy.
Pyke, R. M., Abbott, C., Dea, S., Bedi, N., Colevas, A. D., Levy, E., … Boyle, S. M. (2021). Association of HLA loss of heterozygosity with allele-specific neoantigen expansion in response to immunotherapy. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Treatment patterns for patients with metastatic or recurrent head and neck cancer in a large integrated health-care system.
Seto, T., Samant, N. D., Shah, N., Shirazi, A., Colevas, A. D., & Katzel, J. A. (2021). Treatment patterns for patients with metastatic or recurrent head and neck cancer in a large integrated health-care system. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Skull base osteomyelitis in patients with head and neck cancer: Diagnosis, management, and outcomes in a case series of 23 patients
Czech, M. M., Hwang, P. H., Colevas, A. D., Fischbein, N., & Ho, D. Y. (2022). Skull base osteomyelitis in patients with head and neck cancer: Diagnosis, management, and outcomes in a case series of 23 patients. LARYNGOSCOPE INVESTIGATIVE OTOLARYNGOLOGY. -
Metastatic Parotid Gland Carcinoma With ERBB2 Amplification With Complete Response to Fam-Trastuzumab Deruxtecan.
Shukla, N. D., Chiang, R. S., & Colevas, A. D. (2022). Metastatic Parotid Gland Carcinoma With ERBB2 Amplification With Complete Response to Fam-Trastuzumab Deruxtecan. Journal of the National Comprehensive Cancer Network : JNCCN, 20(2), 102–104. -
Skull base osteomyelitis in patients with head and neck cancer: Diagnosis, management, and outcomes in a case series of 23 patients.
Czech, M. M., Hwang, P. H., Colevas, A. D., Fischbein, N., & Ho, D. Y. (2022). Skull base osteomyelitis in patients with head and neck cancer: Diagnosis, management, and outcomes in a case series of 23 patients. Laryngoscope Investigative Otolaryngology, 7(1), 47–59. -
NCCN Guidelines Insights: Head and Neck Cancers, Version 1.2022.
Caudell, J. J., Gillison, M. L., Maghami, E., Spencer, S., Pfister, D. G., Adkins, D., … Darlow, S. D. (2022). NCCN Guidelines Insights: Head and Neck Cancers, Version 1.2022. Journal of the National Comprehensive Cancer Network : JNCCN, 20(3), 224–234. -
Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141
Gillison, M. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Ferris, R. L. (2022). Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141. ONCOLOGIST, 27(2), E194–E198. -
A Phase 2 Study of Magrolimab Combination Therapy in Patients with Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma
Colevas, A. D., Park, J. J., Fang, B., Shao, J., U'Ren, L., Odegard, J., … Adkins, D. (2022). A Phase 2 Study of Magrolimab Combination Therapy in Patients with Recurrent or Metastatic Head and Neck Squamous-Cell Carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
AI-ASSISTED WHOLE-BODY ASSESSMENT OF IMMUNOTHERAPY RESPONSE USING [18F]F-ARAG, A PET AGENT FOR ACTIVATED T CELLS
Levi, J., Perk, T., Huynh, L., Packiasamy, J., Cheng, S., Sunwoo, J., & Colevas, A. D. (2021). AI-ASSISTED WHOLE-BODY ASSESSMENT OF IMMUNOTHERAPY RESPONSE USING [18F]F-ARAG, A PET AGENT FOR ACTIVATED T CELLS. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
A PHASE 1 TRIAL OF CUE-101, A NOVEL HPV16 E7-PHLA-IL2-FC FUSION PROTEIN, ALONE AND IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH RECURRENT/METASTATIC HPV16+HEAD AND NECK CANCER
Chung, C., Colevas, A. D., Gibson, M., Adkins, D., Sukari, A., Wirth, L., … Pai, S. (2021). A PHASE 1 TRIAL OF CUE-101, A NOVEL HPV16 E7-PHLA-IL2-FC FUSION PROTEIN, ALONE AND IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH RECURRENT/METASTATIC HPV16+HEAD AND NECK CANCER. JOURNAL FOR IMMUNOTHERAPY OF CANCER. BMJ PUBLISHING GROUP. -
A phase II study of tarloxotinib (a hypoxia activated prodrug of a pan-erb tyrosine kinase inhibitor) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or skin.
McLean, L. S., Morris, T. A., Gramza, A., Liu, S., Khan, S. A., Colevas, A. D., … Rischin, D. (2022). A phase II study of tarloxotinib (a hypoxia activated prodrug of a pan-erb tyrosine kinase inhibitor) in patients with recurrent or metastatic squamous cell carcinoma of the head and neck or skin. Investigational New Drugs. -
Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141.
Gillison, M. L., Blumenschein, G., Fayette, J., Guigay, J., Colevas, A. D., Licitra, L., … Ferris, R. L. (2022). Long-term Outcomes with Nivolumab as First-line Treatment in Recurrent or Metastatic Head and Neck Cancer: Subgroup Analysis of CheckMate 141. The Oncologist, 27(2), e194–e198. -
Immunotherapy for Keratinocyte Cancers. Part 1: Immune-Related Epidemiology, Risk Factors, Pathogenesis, and Immunotherapy Management of Keratinocytic Cancers
Neuner, R., Lee, J., Park, C., Rieger, K. E., Colevas, A. D., & Chang, A. S. (2023). Immunotherapy for Keratinocyte Cancers. Part 1: Immune-Related Epidemiology, Risk Factors, Pathogenesis, and Immunotherapy Management of Keratinocytic Cancers. Journal of the American Academy of Dermatology, 88(6). -
HPV DNA as a biomarker in oropharyngeal cancer: A step in the right direction.
Colevas, A. D. (2022). HPV DNA as a biomarker in oropharyngeal cancer: A step in the right direction. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Posttreatment FDG-PET/CT Hopkins criteria predict locoregional recurrence after definitive radiotherapy for oropharyngeal squamous cell carcinoma.
Miller, J. A., Moradi, F., Sundaram, V., Liang, R., Zhang, C., Nguyen, N. K., … Gensheimer, M. F. (2022). Posttreatment FDG-PET/CT Hopkins criteria predict locoregional recurrence after definitive radiotherapy for oropharyngeal squamous cell carcinoma. Head & Neck. -
89Zr-panitumumab combined with 18F-FDG-PET improves detection and staging of head and neck squamous cell carcinoma.
Lee, Y.-J., van den Berg, N. S., Duan, H., Azevedo, E. C., Ferri, V., Hom, M., … Rosenthal, E. L. (2022). 89Zr-panitumumab combined with 18F-FDG-PET improves detection and staging of head and neck squamous cell carcinoma. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Safety of nivolumab added to chemoradiotherapy platforms for intermediate and high-risk local-regionally advanced head and neck squamous cell carcinoma: RTOG Foundation 3504.
Gillison, M. L., Ferris, R. L., Harris, J., Colevas, A. D., Mell, L. K., Kong, C., … Le, Q. T. (2022). Safety of nivolumab added to chemoradiotherapy platforms for intermediate and high-risk local-regionally advanced head and neck squamous cell carcinoma: RTOG Foundation 3504. International Journal of Radiation Oncology, Biology, Physics. -
Immune-related adverse effects of long-term PD-1/PD-L1 inhibtor treatment
Kim, S., Colevas, A. D., Tse, S., On, S., & Cheung, E. (2022). Immune-related adverse effects of long-term PD-1/PD-L1 inhibtor treatment. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A randomized, controlled, open-label, phase 2 study of cemiplimab +/- RP1 in patients with advanced cutaneous squamous cell carcinoma (CERPASS).
Haydon, A. M., Khushalani, N. I., Robert, C., Brungs, D., Collichio, F. A., Colevas, A. D., … Migden, M. R. (2022). A randomized, controlled, open-label, phase 2 study of cemiplimab +/- RP1 in patients with advanced cutaneous squamous cell carcinoma (CERPASS). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A phase 1b/2 study of nanatinostat and valganciclovir in patients with advanced Epstein-Barr virus positive (EBV+) solid tumors and in combination with pembrolizumab in patients with recurrent/metastatic nasopharyngeal carcinoma (RM-NPC).
Colevas, A. D., Siu, L. L., Lim, D. W.-T., Gao, B., Rojkjaer, L., Katkov, A., … Ma, B. (2022). A phase 1b/2 study of nanatinostat and valganciclovir in patients with advanced Epstein-Barr virus positive (EBV+) solid tumors and in combination with pembrolizumab in patients with recurrent/metastatic nasopharyngeal carcinoma (RM-NPC). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A phase 1 dose-escalation and expansion study of CUE-101, a novel HPV16 E7-pHLA-IL2-Fc fusion protein, given alone and in combination with pembrolizumab in patients with recurrent/metastatic HPV16+head and neck cancer.
Chung, C. H., Colevas, A. D., Adkins, D., Gibson, M. K., Rodriguez, C. P., Sukari, A., … Pai, S. I. (2022). A phase 1 dose-escalation and expansion study of CUE-101, a novel HPV16 E7-pHLA-IL2-Fc fusion protein, given alone and in combination with pembrolizumab in patients with recurrent/metastatic HPV16+head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradiation.
Jun, M., Pinto, H., Le, Q.-T. T., Quon, A., Hara, W., Coty, J., … Colevas, A. D. (2023). In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradiation. PloS One, 18(2), e0276651. -
Long-term Outcomes of Bevacizumab and Chemoradiation for Locoregionally Advanced Nasopharyngeal Carcinoma: A Nonrandomized Controlled Trial.
Lee, N. Y., Harris, J., Kim, J., Garden, A., Mechalakos, J., Pfister, D. G., … Le, Q.-T. (2023). Long-term Outcomes of Bevacizumab and Chemoradiation for Locoregionally Advanced Nasopharyngeal Carcinoma: A Nonrandomized Controlled Trial. JAMA Network Open, 6(6), e2316094. -
7-UP: Generating in silico CODEX from a small set of immunofluorescence markers.
Wu, E., Trevino, A. E., Wu, Z., Swanson, K., Kim, H. J., D'Angio, H. B., … Zou, J. (2023). 7-UP: Generating in silico CODEX from a small set of immunofluorescence markers. PNAS Nexus, 2(6), pgad171. -
Concurrent chemoradiotherapy followed by adjuvant cisplatin-gemcitabine versus cis-platin-5-fluorouracil chemotherapy for N2-3 nasopharyngeal carcinoma: A multicentre, open-label, randomised, controlled, phase 3 trial.
Tang, L.-Q., Liu, L.-T., Liu, H., Huang, Y., Jin, F., Xie, S.-Y., … Colevas, A. D. D. (2023). Concurrent chemoradiotherapy followed by adjuvant cisplatin-gemcitabine versus cis-platin-5-fluorouracil chemotherapy for N2-3 nasopharyngeal carcinoma: A multicentre, open-label, randomised, controlled, phase 3 trial. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A phase 1 dose-escalation and expansion study of CUE-101, a novel HPV16 E7-pHLA-IL2-Fc fusion protein, given as monotherapy and in combination with pembrolizumab in patients with recurrent/metastatic HPV16+head and neck cancer.
Chung, C. H., Colevas, A. D. D., Adkins, D., Rodriguez, C. P., Park, J. C., Gibson, M. K., … Pai, S. I. (2023). A phase 1 dose-escalation and expansion study of CUE-101, a novel HPV16 E7-pHLA-IL2-Fc fusion protein, given as monotherapy and in combination with pembrolizumab in patients with recurrent/metastatic HPV16+head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Phase I/IIa clinical trial of a small molecule EBNA1 inhibitor, VK-2019, in patients with Epstein Barr virus-positive nasopharyngeal cancer with pharmacokinetic and pharmacodynamic correlative studies.
Colevas, A. D. D., Rudek, M. A., Even, C., Lee, V. H.-F., Gillison, M. L., Khan, S. A., … Messick, T. (2023). Phase I/IIa clinical trial of a small molecule EBNA1 inhibitor, VK-2019, in patients with Epstein Barr virus-positive nasopharyngeal cancer with pharmacokinetic and pharmacodynamic correlative studies. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A phase 2 study of magrolimab combination therapy in patients with recurrent or metastatic head and neck squamous cell carcinoma: ELEVATE HNSCC
Colevas, A. D. D., Dinis, J. P., Chin, V. T., Costa, D. A., Park, J. J., Fang, B., … Adkins, D. (2023). A phase 2 study of magrolimab combination therapy in patients with recurrent or metastatic head and neck squamous cell carcinoma: ELEVATE HNSCC. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Platinum/taxane/pembrolizumab vs platinum/5FU/pembrolizumab in patients with recurrent/metastatic (r/m) head and neck squamous cell carcinoma (HNSCC).
Sun, L., Cohen, R. B., & Colevas, A. D. D. (2023). Platinum/taxane/pembrolizumab vs platinum/5FU/pembrolizumab in patients with recurrent/metastatic (r/m) head and neck squamous cell carcinoma (HNSCC). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Validation of a robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of VK-2019, a selective EBNA1 inhibitor.
Davis, M. T., Anders, N. M., Colevas, A. D., Messick, T. E., & Rudek, M. A. (2023). Validation of a robust and rapid liquid chromatography tandem mass spectrometric method for the quantitative analysis of VK-2019, a selective EBNA1 inhibitor. Biomedical Chromatography : BMC, e5775. -
A phase Ib/II study of nanatinostat (Nstat) plus valganciclovir (VGCV) in EBV plus solid tumors and with pembrolizumab (PEM) in recurrent/metastatic nasopharyngeal carcinoma (R/M NPC)
Colevas, A. D., Siu, L., Lim, D. W.-T., Gao, B., Voon, P.-J., Khan, S., … Ma, B. (2023). A phase Ib/II study of nanatinostat (Nstat) plus valganciclovir (VGCV) in EBV plus solid tumors and with pembrolizumab (PEM) in recurrent/metastatic nasopharyngeal carcinoma (R/M NPC). ANNALS OF ONCOLOGY. ELSEVIER. -
A novel mitochondrial-targeted [18F]F-AraG positron emission tomography (PET) biomarker for early diagnosis and monitoring of cardiotoxicity
Shrestha, U., Chae, H., Blecha, J., Colevas, A. D., Sunwoo, J., VanBrocklin, H., … Seo, Y. (2023). A novel mitochondrial-targeted [18F]F-AraG positron emission tomography (PET) biomarker for early diagnosis and monitoring of cardiotoxicity. JOURNAL OF NUCLEAR MEDICINE. SOC NUCLEAR MEDICINE INC. -
Nasopharyngeal cancer mortality in disaggregated Asian and non-Asian Americans.
Hung, G. A., Vohra, S., Kim, G., Jamal, A., Srinivasan, M., Huang, R. J., … Colevas, A. D. (2024). Nasopharyngeal cancer mortality in disaggregated Asian and non-Asian Americans. Head & Neck. -
Nasopharyngeal cancer mortality in disaggregated Asian and non-Asian Americans
Hung, G. A., Vohra, S., Kim, G., Jamal, A., Srinivasan, M., Huang, R. J., … Colevas, A. D. (2024). Nasopharyngeal cancer mortality in disaggregated Asian and non-Asian Americans. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A phase 1 dose-escalation and expansion study of CUE-101, given as monotherapy and in combination with pembrolizumab, in patients with recurrent/metastatic HPV16+head and neck squamous cell cancer (R/M HNSCC).
Colevas, A. D., Chung, C. H., Adkins, D., Rodriguez, C. P., Park, J. C., Gibson, M. K., … Pai, S. I. (2024). A phase 1 dose-escalation and expansion study of CUE-101, given as monotherapy and in combination with pembrolizumab, in patients with recurrent/metastatic HPV16+head and neck squamous cell cancer (R/M HNSCC). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Safety of tabelecleucel with pembrolizumab in recurrent/metastatic Epstein-Barr virus-associated nasopharyngeal carcinoma
Colevas, A. D., Cohen, R. B., Park, J. C., Pfister, D. G., Massarelli, E., Li, Z., … Mehta, A. (2024). Safety of tabelecleucel with pembrolizumab in recurrent/metastatic Epstein-Barr virus-associated nasopharyngeal carcinoma. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
A phase 2 study of ipatasertib in combination with pembrolizumab for first-line treatment of recurrent or metastatic squamous cell cancer of the head and neck
Thomas, J. S., Bruce, J. Y., Li, Z., Lorch, J. H., Phillips, T., Villaflor, V., … Colevas, A. D. (2024). A phase 2 study of ipatasertib in combination with pembrolizumab for first-line treatment of recurrent or metastatic squamous cell cancer of the head and neck. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Platinum/taxane/pembrolizumab vs platinum/5FU/pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma (r/m HNSCC).
Sun, L., Cohen, R. B., & Dimitrios Colevas, A. (2024). Platinum/taxane/pembrolizumab vs platinum/5FU/pembrolizumab in recurrent/metastatic head and neck squamous cell carcinoma (r/m HNSCC). Oral Oncology, 158, 106997. -
Gemcitabine, carboplatin, and Epstein Barr virus-specific autologous cytotoxic T lymphocytes for recurrent or metastatic nasopharyngeal carcinoma: VANCE, an international randomized Phase 3 trial.
Toh, H. C., Yang, M.-H. H., Wang, H.-M. M., Hsieh, C. Y., Chitapanarux, I., Ho, K. F., … Samol, J. (2024). Gemcitabine, carboplatin, and Epstein Barr virus-specific autologous cytotoxic T lymphocytes for recurrent or metastatic nasopharyngeal carcinoma: VANCE, an international randomized Phase 3 trial. Annals of Oncology : Official Journal of the European Society for Medical Oncology. -
Automated patient selection and care coaches to increase advance care planning for cancer patients.
Gensheimer, M. F., Teuteberg, W., Patel, M. I., Gupta, D., Noroozi, M., Ling, X., … Ramchandran, K. (2024). Automated patient selection and care coaches to increase advance care planning for cancer patients. Journal of the National Cancer Institute. -
Ninth Version of the AJCC and UICC Nasopharyngeal Cancer TNM Staging Classification.
Pan, J.-J. J., Mai, H.-Q. Q., Ng, W. T., Hu, C.-S. S., Li, J.-G. G., Chen, X.-Z. Z., … Lee, A. W. (2024). Ninth Version of the AJCC and UICC Nasopharyngeal Cancer TNM Staging Classification. JAMA Oncology. -
Platinum/taxane/pembrolizumab vs Platinum/5-fluorouracil/pembrolizumab in recurrent/metastatic Head and Neck Squamous Cell Carcinoma (r/m HNSCC)
Sun, L., Cohen, R., & Colevas, A. D. (2024). Platinum/taxane/pembrolizumab vs Platinum/5-fluorouracil/pembrolizumab in recurrent/metastatic Head and Neck Squamous Cell Carcinoma (r/m HNSCC). INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
A Phase 1 Dose-escalation and Expansion Study of CUE 101, Given As Monotherapy in 3<SUP>rd</SUP> Line and in Combination with Pembrolizumab in 1<SUP>st</SUP> Line Recurrent/Metastatic (R/M) HPV16+Head and Neck Cancer Patients
Colevas, A. D., Chung, C. H., Adkins, D., Rodriguez, C. P., Park, J. C., Gibson, M. K., … Pai, S. I. (2024). A Phase 1 Dose-escalation and Expansion Study of CUE 101, Given As Monotherapy in 3rd Line and in Combination with Pembrolizumab in 1st Line Recurrent/Metastatic (R/M) HPV16+Head and Neck Cancer Patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Safety and Tolerability of Magrolimab Combination Therapy in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (RM-HNSCC)
Colevas, A. D., Kerrigan, K., Chin, V., Rainey, N., Park, J. J., Fang, B., … Adkins, D. (2024). Safety and Tolerability of Magrolimab Combination Therapy in Patients with Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (RM-HNSCC). INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC. -
Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study.
Flanagan, K. C., Earls, J., Hiken, J., Wellinghoff, R. L., Ponder, M. M., McLeod, H. L., … Duncavage, E. J. (2024). Multicenter validation of an RNA-based assay to predict anti-PD-1 disease control in patients with recurrent or metastatic head and neck squamous cell carcinoma: the PREDAPT study. Journal for Immunotherapy of Cancer, 12(11). -
A Survival Analysis of Patients with Radiation -Induced Cancers after Prior Radiation for Head and Neck Cancer
Laseinde, E., Guan, L., Hildebrand, R., Meurice, N., Gensheimer, M. F., Beadle, B. M., … Le, Q. T. (2024). A Survival Analysis of Patients with Radiation -Induced Cancers after Prior Radiation for Head and Neck Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. ELSEVIER SCIENCE INC.
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Phase II trial of docetaxel, cisplatin, fluorouracil, and leucovorin as induction for squamous cell carcinoma of the head and neck
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1
- Clinical Trial of a Novel Small Molecule EBNA1 Inhibitor, VK 2019, in Patients With Epstein Barr Virus (EBV)-Positive Nasopharyngeal Cancer (NPC) and Other Epstein-Barr Virus (EBV)-Associated Cancers, With Pharmacokinetic and Pharmacodynamic Correlative Studies
- A Multicenter Cancer Biospecimen Collection Study
- Testing the Addition of an Anti-cancer Drug, Ipatasertib, to the Usual Immunotherapy Treatment (Pembrolizumab) in Patients With Recurrent or Metastatic Squamous Cell Cancer of the Head and Neck
- Study of CHS-114 in Participants With Advanced Solid Tumors
- Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer
- Phase II Trial of Pembrolizumab in Metastatic or Locally Advanced Anaplastic/Undifferentiated Thyroid Cancer
- A Phase 2 Open Label Study of BA3021 in Patients with Recurrent or Metastatic Squamous Cell Carcinoma of the Head and Neck
- Study Evaluating Cemiplimab Alone and Combined With RP1 in Treating Advanced Squamous Skin Cancer
- Study of Magrolimab Combination Therapy in Patients With Head and Neck Squamous Cell Carcinoma
- A Phase 1 Study in Patients With HPV16+ Recurrent/ Metastatic Head and Neck Squamous Cell Carcinoma
- Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer
- A Study of the Safety, Tolerability and Pharmacokinetics of ABBV-368 as a Single Agent and Combination in Subjects With Locally Advanced or Metastatic Solid Tumors
- Phase 1/2a Study of VK-2019 in Patients With Epstein-Barr Virus (EBV)-Positive Nasopharyngeal Carcinoma (NPC)
- Nanatinostat Plus Valganciclovir in Patients With Advanced EBV+ Solid Tumors, and in Combination With Pembrolizumab in EBV+ RM-NPC
- INCAGN01876 in Combination With Immunotherapy in Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Practice Locations
Head and Neck Cancer Program at 900 Blake Wilbur Palo Alto, CA
Palo Alto, CAHead and Neck Cancer Program at 900 Blake Wilbur
900 Blake Wilbur Dr
Palo Alto , CA 94304
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Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
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