Joshua W. Knowles

Joshua W. Knowles

Cardiologist

Bio:   Josh Knowles is a physician-scientist and the overall theme my research has been the genetic basis of cardiovascular disease across the continuum from Discovery to the development of Model Systems to the Translation of these findings to the clinic and most recently to the Public Health aspect of genetics. He completed his MD-PhD at UNC with Prof. Nobuyo Maeda and Nobel Laureate Oliver Smithies. He did Internal Medicine residency and Cardiology fellowship training at Stanford working with Dr. Tom Quertermous. Currently his Discovery and basic translational efforts center on understanding the genetic basis of insulin resistance using GWAS studies coupled with exploration in model systems. His clinical translational focus is on Familial Hypercholesterolemia (FH) and he is the volunteer Chief Medical Advisor of the FH Foundation (FHF) which is a patient-led organization dedicated to increasing awareness of FH, identifying and treating patients with FH and screening family members to prevent deleterious outcomes. He helped lead the FHF efforts to establish a national patient registry (CASCADE FH), apply for an ICD10 code for FH and is now using cutting-edge “big-data” approaches to identify previously undiagnosed FH patients in electronic medical records (FIND FH). He has published over 90 papers with research projects currently funded by the National Institutes of Health, the American Heart Association and the Doris Duke Charitable Foundation.
4.8 out of 5
52 Patient Ratings
17 Patient Comments

Preventive Cardiology

  • 300 Pasteur Drive
  • 2nd Floor, Room A260
  • Stanford , CA 94305
  • Phone: 650-723-6459
More Clinic Information » Getting Here » Make An Appointment

Center for Inherited Cardiovascular Disease

  • 300 Pasteur Drive
  • 2nd Floor, Room H2157
  • Stanford , CA 94305
  • Phone: 650-721-4363
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Hypertrophic Cardiomyopathy Center

  • 300 Pasteur Drive
  • 2nd Floor, Room A260
  • Stanford , CA 94305
  • Phone: 650-723-6459
More Clinic Information » Getting Here » Make An Appointment

Professional Education

  • Board Certification: Cardiovascular Disease, American Board of Internal Medicine (2010)
  • Fellowship: Stanford University School of Medicine (2010) CA
  • Residency: Stanford University School of Medicine (2005) CA
  • Medical Education: University of North Carolina - Chapel Hill (2003) NC
  • PhD, University of North Carolina, Chapel Hill, Genetics and Molecular Biology (2001)

Honors & Awards

  • Alderman Award for Excellence in Clinical Research, Stanford Cardiovascular Medicine (2008, 2009)
  • Clinical Scholar, Doris Duke Charitable Foundation (6/1/16-6/1/19)
  • Dean's Fellowship, Stanford (2005)
  • Diplomate, National Lipid Association (2012)
  • Fellow, ACC (2012)
  • Fellow, AHA (2012)
  • Fellowship Award, Future Leaders in CV Medicine (2006)
  • National Fellow to Faculty Transition Award, AHA (7/1/10-7/1/15)
  • National Innovative Research Award, AHA

Administrative Appointments

  • Chief, Translational Medicine, The FH Foundation (2012 - Present)
  • Co-Director, Translational Investigator Program (2017 - Present)
  • Co-Section Chief. Metabolism and Insulin Signaling, Stanford Diabetes Research Center` (2017 - Present)
  • Program Director, Cardiovascular Medicine Fellowship Program (2018 - Present)

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4.9

Friendliness

4.8

Explanations

4.8

Listens

4.8

Includes you in decisions

4.8

Clear Communication

4.9

Confidence in your doctor

4.9

Recommended to others

4.5

Wait times

SHC Patient, Apr 2018

Exceeded expectations, very thorough, knowledgeable (I am a physician).

SHC Patient, Aug 2017

Told friends "Stanford is the best!

SHC Patient, Jun 2017

Very good.

SHC Patient, May 2017

Dr. Knowles spent quite a lot of time on my history and in explaining what I needed to do to improve and extend health, and motivating me to be more proactive in doing it.

SHC Patient, May 2017

Everyone was very caring & nice.

SHC Patient, Apr 2017

Doctor was great and took the time to go over details with me.

SHC Patient, Mar 2017

Very thoughtful and informed discussion of treatment options.

SHC Patient, Aug 2016

Good experience.

SHC Patient, Jul 2016

Dr. Knowles and Ms. Lamendola both are consummate professionals.

SHC Patient, Jul 2016

Dr. Knowles was outstanding!

SHC Patient, May 2016

Dr. Knowles is friendly, thorough, kind, professional, and shares his expertise in a clear and genuine manner.

SHC Patient, Dec 2015

Great doctor.

View All 17 Patient Comments »
4.8 out of 5
52 Patient Ratings
17 Patient Comments

SHC Patient, Apr 2018

Exceeded expectations, very thorough, knowledgeable (I am a physician).

SHC Patient, Aug 2017

Told friends "Stanford is the best!

SHC Patient, Jun 2017

Very good.

SHC Patient, May 2017

Dr. Knowles spent quite a lot of time on my history and in explaining what I needed to do to improve and extend health, and motivating me to be more proactive in doing it.

SHC Patient, May 2017

Everyone was very caring & nice.

SHC Patient, Apr 2017

Doctor was great and took the time to go over details with me.

SHC Patient, Mar 2017

Very thoughtful and informed discussion of treatment options.

SHC Patient, Aug 2016

Good experience.

SHC Patient, Jul 2016

Dr. Knowles and Ms. Lamendola both are consummate professionals.

SHC Patient, Jul 2016

Dr. Knowles was outstanding!

SHC Patient, May 2016

Dr. Knowles is friendly, thorough, kind, professional, and shares his expertise in a clear and genuine manner.

SHC Patient, Dec 2015

Great doctor.

SHC Patient, Apr 2015

I cannot tell you how thankful I am that I am able to have such good drs. & PA's. Its a comfort.

SHC Patient, Jan 2015

I felt like I didn't fit his "study" protocol so he wasn't interested in me anymore.

SHC Patient, Dec 2014

He was very informative.

SHC Patient, Dec 2013

My doc didn't give info on my meds b/c he didn't prescribe them.

SHC Patient, Dec 2013

He was amazing!