Joshua W. Knowles

Cardiologist

Assistant Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center
Bio:   The fundamental theme of my work is the application of genetics to improve human health. I view this as a continuum from Discovery -> to the development of Model Systems -> to clinical Translation -> to larger Public Health efforts. Much of my work focuses on discovery of genetic variants underlying cardiovascular disease, particularly coronary disease and insulin resistance through large international studies. We are now creating human induced pluripotent stem cell (iPSC) lines to model the genetic networks that produce disease. We are translating these findings to the clinic in a randomized trial where we are asking if we can improve an individual’s risk by giving them information about their inherited risk of heart disease. Finally, as the Chief Medical Advisor for a patient-led, non-profit (The FH Foundation, www.thefhfoundation.org), we are attempting to raise the profile of familial hypercholesterolemia (FH), an inherited disease that causes extremely elevated LDL cholesterol levels and risk of coronary disease. We have partnered with patients and organizations like the CDC, ACC and AHA to increase public health awareness of FH and have recently launched a national patient registry called “CASCADE FH”.
4.8 out of 5
76 Patient Ratings
4 Patient Comments

Preventive Cardiology

  • 300 Pasteur Drive
  • 2nd Floor, Room A260
  • Stanford, CA 94305
  • Phone: 650-723-6459
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Center for Inherited Cardiovascular Disease

  • 300 Pasteur Drive
  • 2nd Floor, Room H2157
  • Stanford, CA 94305
  • Phone: 650-721-4363
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Hypertrophic Cardiomyopathy Center

  • 300 Pasteur Drive
  • 2nd Floor, Room A260
  • Stanford, CA 94305
  • Phone: 650-723-6459
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Professional Education

  • Fellowship: Stanford University School of Medicine (2010) CA
  • Residency: Stanford University School of Medicine (2005) CA
  • Board Certification: Cardiovascular Disease, American Board of Internal Medicine (2010)
  • Medical Education: University of North Carolina - Chapel Hill (2003) NC
  • PhD, University of North Carolina, Chapel Hill, Genetics and Molecular Biology (2001)
  • Board Certification: Internal Medicine, American Board of Internal Medicine (2006)

Honors & Awards

  • National Fellow to Faculty Transition Award, AHA (7/1/10-7/1/15)
  • Fellow, ACC (2012)
  • Fellow, AHA (2012)
  • Diplomate, National Lipid Association (2012)
  • Alderman Award for Excellence in Clinical Research, Stanford Cardiovascular Medicine (2008, 2009)
  • Fellowship Award, Future Leaders in CV Medicine (2006)
  • Dean's Fellowship, Stanford (2005)

Administrative Appointments

  • Chief Medical Officer, The FH Foundation (2012 - Present)

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

4.8

Friendliness

4.8

Recommended to others

4.9

Explanations

4.8

Listens

4.8

Includes you in decisions

4.9

Clear Communication

4.9

Confidence in your doctor

4.4

Wait times

SHC Patient, Jan 2015

I felt like I didn't fit his "study" protocol so he wasn't interested in me anymore.

SHC Patient, Dec 2014

He was very informative.

SHC Patient, Dec 2013

My doc didn't give info on my meds b/c he didn't prescribe them.

SHC Patient, Dec 2013

He was amazing!

4.8 out of 5
76 Patient Ratings
4 Patient Comments

SHC Patient, Jan 2015

I felt like I didn't fit his "study" protocol so he wasn't interested in me anymore.

SHC Patient, Dec 2014

He was very informative.

SHC Patient, Dec 2013

My doc didn't give info on my meds b/c he didn't prescribe them.

SHC Patient, Dec 2013

He was amazing!