Joshua W. Knowles

Joshua W. Knowles

Cardiologist

Bio:   The fundamental theme of my work is the application of genetics to improve human health. I view this as a continuum from Discovery -> to the development of Model Systems -> to clinical Translation -> to larger Public Health efforts. Much of my work focuses on discovery of genetic variants underlying cardiovascular disease, particularly coronary disease and insulin resistance through large international studies. We are now creating human induced pluripotent stem cell (iPSC) lines to model the genetic networks that produce disease. We are translating these findings to the clinic in a randomized trial where we are asking if we can improve an individual’s risk by giving them information about their inherited risk of heart disease. Finally, as the Chief Medical Advisor for a patient-led, non-profit (The FH Foundation, www.thefhfoundation.org), we are attempting to raise the profile of familial hypercholesterolemia (FH), an inherited disease that causes extremely elevated LDL cholesterol levels and risk of coronary disease. We have partnered with patients and organizations like the CDC, ACC and AHA to increase public health awareness of FH and have recently launched a national patient registry called “CASCADE FH”.
4.8 out of 5
59 Patient Ratings
15 Patient Comments

Preventive Cardiology

  • 300 Pasteur Drive
  • 2nd Floor, Room A260
  • Stanford , CA 94305
  • Phone: 650-723-6459
More Clinic Information » Getting Here » Make An Appointment

Center for Inherited Cardiovascular Disease

  • 300 Pasteur Drive
  • 2nd Floor, Room H2157
  • Stanford , CA 94305
  • Phone: 650-721-4363
More Clinic Information » Getting Here » Make An Appointment

Hypertrophic Cardiomyopathy Center

  • 300 Pasteur Drive
  • 2nd Floor, Room A260
  • Stanford , CA 94305
  • Phone: 650-723-6459
More Clinic Information » Getting Here » Make An Appointment

Professional Education

  • Board Certification: Cardiovascular Disease, American Board of Internal Medicine (2010)
  • Fellowship: Stanford University School of Medicine (2010) CA
  • Residency: Stanford University School of Medicine (2005) CA
  • Medical Education: University of North Carolina - Chapel Hill (2003) NC
  • PhD, University of North Carolina, Chapel Hill, Genetics and Molecular Biology (2001)

Honors & Awards

  • Alderman Award for Excellence in Clinical Research, Stanford Cardiovascular Medicine (2008, 2009)
  • Clinical Scholar, Doris Duke Charitable Foundation (6/1/16-6/1/19)
  • Dean's Fellowship, Stanford (2005)
  • Diplomate, National Lipid Association (2012)
  • Fellow, ACC (2012)
  • Fellow, AHA (2012)
  • Fellowship Award, Future Leaders in CV Medicine (2006)
  • National Fellow to Faculty Transition Award, AHA (7/1/10-7/1/15)
  • National Innovative Research Award, AHA

Administrative Appointments

  • Chief Medical Advisor, The FH Foundation (2012 - Present)

Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.

Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.

4.7

Friendliness

4.8

Explanations

4.7

Listens

4.7

Includes you in decisions

4.7

Clear Communication

4.8

Confidence in your doctor

4.8

Recommended to others

4.4

Wait times

SHC Patient, Jun 2017

Very good.

SHC Patient, May 2017

Dr. Knowles spent quite a lot of time on my history and in explaining what I needed to do to improve and extend health, and motivating me to be more proactive in doing it.

SHC Patient, May 2017

Everyone was very caring & nice.

SHC Patient, Apr 2017

Doctor was great and took the time to go over details with me.

SHC Patient, Mar 2017

Very thoughtful and informed discussion of treatment options.

SHC Patient, Aug 2016

Good experience.

SHC Patient, Jul 2016

Dr. Knowles and Ms. Lamendola both are consummate professionals.

SHC Patient, Jul 2016

Dr. Knowles was outstanding!

SHC Patient, May 2016

Dr. Knowles is friendly, thorough, kind, professional, and shares his expertise in a clear and genuine manner.

SHC Patient, Dec 2015

Great doctor.

SHC Patient, Apr 2015

I cannot tell you how thankful I am that I am able to have such good drs. & PA's. Its a comfort.

SHC Patient, Jan 2015

I felt like I didn't fit his "study" protocol so he wasn't interested in me anymore.

View All 15 Patient Comments »
4.8 out of 5
59 Patient Ratings
15 Patient Comments

SHC Patient, Jun 2017

Very good.

SHC Patient, May 2017

Dr. Knowles spent quite a lot of time on my history and in explaining what I needed to do to improve and extend health, and motivating me to be more proactive in doing it.

SHC Patient, May 2017

Everyone was very caring & nice.

SHC Patient, Apr 2017

Doctor was great and took the time to go over details with me.

SHC Patient, Mar 2017

Very thoughtful and informed discussion of treatment options.

SHC Patient, Aug 2016

Good experience.

SHC Patient, Jul 2016

Dr. Knowles and Ms. Lamendola both are consummate professionals.

SHC Patient, Jul 2016

Dr. Knowles was outstanding!

SHC Patient, May 2016

Dr. Knowles is friendly, thorough, kind, professional, and shares his expertise in a clear and genuine manner.

SHC Patient, Dec 2015

Great doctor.

SHC Patient, Apr 2015

I cannot tell you how thankful I am that I am able to have such good drs. & PA's. Its a comfort.

SHC Patient, Jan 2015

I felt like I didn't fit his "study" protocol so he wasn't interested in me anymore.

SHC Patient, Dec 2014

He was very informative.

SHC Patient, Dec 2013

My doc didn't give info on my meds b/c he didn't prescribe them.

SHC Patient, Dec 2013

He was amazing!