Biography
She currently co-chairs the NRG Oncology Group of the NCI-sponsored National Clinical Trial Network (NCTN), which conducts practice-changing phase II-III trials in many cancers. Before that, she chaired the HNC Committee of NRG Oncology for ten years. She has received grant support from ASCO, ASTRO as well as P01, R01 and R21 grants from the NIH. She has served as a reviewer for several journals and NIH study sections. She has been actively involved in many national and international organizations such as ASTRO, ASCO and AARC and ARS. She was inducted into the Fellowship of the American College of Radiology (FACR), the American Society of Therapeutic Radiology and Oncology (FASTRO) and the Institute of Medicine / National Academy of Medicine (IOM/NAM). She was also honored with the Caltech Distinguished Alumni Award.
Professional Summary
Education & Certifications
- Residency: UCSF Radiation Oncology Residency (1997) CA
- Internship: Alameda County Highland Hospital Internal Medicine Residency (1994) CA
- Medical Education: University of California at San Francisco School of Medicine (1993) CA
- Board Certification: American Board of Radiology, Radiation Oncology (1998)
- MD, UCSF, Medicine (1993)
Honors & Awards
- Distinguished Alumni Award, California Institute of Technology (Caltech) (2015)
- Fellow, American College of Radiology (ACR) (2011)
- Fellow, American Society of Therapeutic Radiation Oncology (ASTRO) (2014)
- Member, Alpha Omega Alpha Medical Honor Society (1993)
- Member, Induction into Institute of Medicine (IOM) (2013)
- Recipient, American Association of Woman Radiologist Early Career Professional Development Award (2002)
- Recipient, ARRO Educator of the Year Award (2014)
- Recipient, ASCO Clinical Research Development Award (2002-2005)
- Recipient, ASTRO Junior Faculty Research Fellowship (2000-2002)
- Recipient, Henry Kaplan Memorial Prize for Teaching Award (1998, 2000)
- Recipient, Radiologic Society of Northern American Resident Research Award (1997)
- Recipient, UCSF Regent Scholarship (1989-1991)
- Top Graduate in Medical School Class, Sadie E. Berkove, MD Fellowship (1993)
Memberships
- Treasurer and Executive Committee Member, American Radium Socieity (2012 - Present)
- Annual Program Committee - Head and Neck Group Member, ASCO (2012 - 2015)
- Chair, Head and Neck Cancer Committee, NRG Oncology Cooperative Group (RTOG, NSABP & GOG) (2011 - Present)
- Chair, Education Committee, ASTRO (2011 - 2015)
- Chair and Member, Scientific Program Committee, American Radium Society (2006 - 2011)
- Editorial Board Member, Journal Clinical Oncology (2006 - 2010)
- Radiology Program Co-Director, Stanford Comprehensive Cancer Center Grant (P30) (2005 - Present)
- Annual Program Committee Member, ASTRO (2004 - 2010)
- Panel Member, National Comprehensive Cancer Network Lung Cancer (2004 - 2010)
- Annual Program Committee - Lung Group Member, ASCO (2004 - 2007)
- Task Force Member of Written Board/Oral Board, American Board of Radiology (2003 - Present)
Administrative Appointments
- Chair, Department of Radiation Oncology, Stanford University (2011 - Present)
- Co-Director, Radiation Biology Program, Stanford Cancer Institute (2004 - Present)
Publications
-
Apoptosis-associated proteins and the development of oral squamous cell carcinoma
Schoelch, M. L., Le, Q. T., Silverman, S., McMillan, A., Dekker, N. P., Fu, K. K., … Regezi, J. A. (1999). Apoptosis-associated proteins and the development of oral squamous cell carcinoma. ORAL ONCOLOGY, 35(1), 77–85. -
Optimization of importance factors in inverse planning
Xing, L., Li, J. G., Donaldson, S., Le, Q. T., & Boyer, A. L. (1999). Optimization of importance factors in inverse planning. PHYSICS IN MEDICINE AND BIOLOGY, 44(10), 2525–36. -
Treatment of maxillary sinus carcinoma - A comparison of the 1997 and 1977 American Joint Committee on Cancer staging systems
Le, Q. T., Fu, K. K., Kaplan, M., Terris, D. J., Fee, W. E., & Goffinet, D. R. (1999). Treatment of maxillary sinus carcinoma - A comparison of the 1997 and 1977 American Joint Committee on Cancer staging systems. CANCER, 86(9), 1700–1711. -
Postoperative irradiation of minor salivary gland malignancies of the head and neck
Le, Q. T., Birdwell, S., Terris, D. J., Gabalski, E. C., Varghese, A., Fee, W. E., & Goffinet, D. R. (1999). Postoperative irradiation of minor salivary gland malignancies of the head and neck. RADIOTHERAPY AND ONCOLOGY, 52(2), 165–171. -
Estimation theory and model parameter selection for therapeutic treatment plan optimization
Xing, L., Li, J. G., Pugachev, A., Le, Q. T., & Boyer, A. L. (1999). Estimation theory and model parameter selection for therapeutic treatment plan optimization. MEDICAL PHYSICS, 26(11), 2348–58. -
Cell cycle proteins and the development of oral squamous cell carcinoma
Schoelch, M. L., Regezi, J. A., Dekker, N. P., Ng, I. O. L., McMillan, A., Ziober, B. L., … Fu, K. K. (1999). Cell cycle proteins and the development of oral squamous cell carcinoma. ORAL ONCOLOGY, 35(3), 333–342. -
Lymph node metastasis in maxillary sinus carcinoma
Le, Q. T., Fu, K. K., Kaplan, M. J., Terris, D. J., Fee, W. E., & Goffinet, D. R. (2000). Lymph node metastasis in maxillary sinus carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 46(3), 541–49. -
Candidate genes for the hypoxic tumor phenotype
Koong, A. C., Denko, N. C., Hudson, K. M., Schindler, C., Swiersz, L., Koch, C., … Giaccia, A. J. (2000). Candidate genes for the hypoxic tumor phenotype. CANCER RESEARCH, 60(4), 883–87. -
Dosimetric effects of patient displacement and collimator and gantry angle misalignment on intensity modulated radiation therapy
Xing, L., Lin, Z. X., Donaldson, S. S., Le, Q. T., Tate, D., Goffinet, D. R., … Boyer, A. L. (2000). Dosimetric effects of patient displacement and collimator and gantry angle misalignment on intensity modulated radiation therapy. RADIOTHERAPY AND ONCOLOGY, 56(1), 97–108. -
DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine.
Dorie, M. J., Kovacs, M. S., Gabalski, E. C., Adam, M., Le, Q. T., Bloch, D. A., … Brown, J. M. (1999). DNA damage measured by the comet assay in head and neck cancer patients treated with tirapazamine. Neoplasia , 1(5), 461–67. -
Head and neck cancer in cardiothoracic transplant recipients
Pollard, J. D., Hanasono, M. M., Mikulec, A. A., Le, Q. T., & Terris, D. J. (2000). Head and neck cancer in cardiothoracic transplant recipients. LARYNGOSCOPE, 110(8), 1257–1261. -
Image-guided radiosurgery for the spine and pancreas.
MURPHY, M. J., Adler, J. R., Bodduluri, M., Dooley, J., Forster, K., Hai, J., … Poen, J. (2000). Image-guided radiosurgery for the spine and pancreas. Computer Aided Surgery , 5(4), 278–88. -
Pancreatic tumors show high levels of hypoxia
Koong, A. C., Mehta, V. K., Le, Q. T., Fisher, G. A., Terris, D. J., Brown, J. M., … Vierra, M. (2000). Pancreatic tumors show high levels of hypoxia. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 48(4), 919–22. -
Treatment results of carcinoma in situ of the glottis - An analysis of 82 cases
Le, Q. T., Takamiya, R., Shu, H. K., Smitt, M., Singer, M., Terris, D. J., … Fu, K. K. (2000). Treatment results of carcinoma in situ of the glottis - An analysis of 82 cases. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 126(11), 1305–1312. -
Role of beam orientation optimization in intensity-modulated radiation therapy
Pugachev, A., Li, J. G., Boyer, A. L., Hancock, S. L., Le, Q. T., Donaldson, S. S., & Xing, L. (2001). Role of beam orientation optimization in intensity-modulated radiation therapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 50(2), 551–60. -
Treatment results and prognostic factors of advanced T3-4 laryngeal carcinoma: The University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience
Nguyen-Tan, P. F., Le, Q. T., Quivey, J. M., Singer, M., Terris, D. J., Goffinet, D. R., & Fu, K. K. (2001). Treatment results and prognostic factors of advanced T3-4 laryngeal carcinoma: The University of California, San Francisco (UCSF) and Stanford University Hospital (SUH) experience. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 50(5), 1172–1180. -
Image-guided hypo-fractionated stereotactic radiosurgery to spinal lesions
Ryu, S. I., Chang, S. D., Kim, D. H., MURPHY, M. J., Le, Q. T., Martin, D. P., & Adler, J. R. (2001). Image-guided hypo-fractionated stereotactic radiosurgery to spinal lesions. NEUROSURGERY, 49(4), 838–46. -
Daily low-dose carboplatin as a radiation sensitizer for newly diagnosed malignant glioma
Peterson, K., Harsh, G., Fisher, P. G., Adler, J., & Le, Q. (2001). Daily low-dose carboplatin as a radiation sensitizer for newly diagnosed malignant glioma. JOURNAL OF NEURO-ONCOLOGY, 53(1), 27–32. -
Primary radiotherapy for localized orbital malt lymphoma
Le, Q. T., Eulau, S. M., George, T. I., Hildebrand, R., Warnke, R. A., Donaldson, S. S., & Hoppe, R. T. (2002). Primary radiotherapy for localized orbital malt lymphoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 52(3), 657–63. -
Tirapazamine: Prototype for a novel class of therapeutic agents targeting tumor hypoxia
Gandara, D. R., Lara, P. N., Goldberg, Z., Le, Q. T., Mack, P. C., Lau, D. H. M., & Gumerlock, P. H. (2002). Tirapazamine: Prototype for a novel class of therapeutic agents targeting tumor hypoxia. SEMINARS IN ONCOLOGY, 29(1), 102–109. -
The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery
Murphy, M. J., Martin, D., Whyte, R., Hai, J., Ozhasoglu, C., & Le, Q. T. (2002). The effectiveness of breath-holding to stabilize lung and pancreas tumors during radiosurgery. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 53(2), 475–82. -
Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay
Terris, D. J., Ho, E. Y., Ibrahim, H. Z., Dorie, M. J., Kovacs, M. S., Le, Q. T., … Brown, J. M. (2002). Estimating DNA repair by sequential evaluation of head and neck tumor radiation sensitivity using the comet assay. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 128(6), 698–702. -
Tumor hypoxia is important in radiotherapy, but how should we measure it?
Brown, J. M., & Le, Q. T. (2002). Tumor hypoxia is important in radiotherapy, but how should we measure it? INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 54(5), 1299–1301. -
Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas
Le, Q. T., Sutphin, P. D., Raychaudhuri, S., Yu, S. C. T., Terris, D. J., Lin, H. S., … Giaccia, A. J. (2003). Identification of osteopontin as a prognostic plasma marker for head and neck squamous cell carcinomas. CLINICAL CANCER RESEARCH, 9(1), 59–67. -
Patterns of patient movement during frameless image-guided radiosurgery
Murphy, M. J., Chang, S. D., Gibbs, I. C., Le, Q. T., Hai, J., Kim, D., … Adler, J. R. (2003). Patterns of patient movement during frameless image-guided radiosurgery. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 55(5), 1400–1408. -
Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial
Whyte, R. I., Crownover, R., MURPHY, M. J., Martin, D. P., Rice, T. W., DeCamp, M. M., … Le, Q. T. (2003). Stereotactic radiosurgery for lung tumors: Preliminary report of a phase I trial. ANNALS OF THORACIC SURGERY, 75(4), 1097–1101. -
Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients
Le, Q. T., Kovacs, M. S., Dorie, M. J., Koong, A., Terris, D. J., Pinto, H. A., … Brown, J. M. (2003). Comparison of the comet assay and the oxygen microelectrode for measuring tumor oxygenation in head-and-neck cancer patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56(2), 375–83. -
Radiation therapy for intracranial germ cell tumors
Haas-Kogan, D. A., Missett, B. T., Wara, W. M., Donaldson, S. S., Lamborn, K. R., Prados, M. D., … Le, Q. T. (2003). Radiation therapy for intracranial germ cell tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56(2), 511–18. -
Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma
Le, Q. T., Tate, D., Koong, A., Gibbs, I. C., Chang, S. D., Adler, J. R., … Goffinet, D. R. (2003). Improved local control with stereotactic radiosurgical boost in patients with nasopharyngeal carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 56(4), 1046–54. -
HIF-alpha, a gender independent transcription factor
Le, Q. T., & Giaccia, A. J. (2003). HIF-alpha, a gender independent transcription factor. CLINICAL CANCER RESEARCH, 9(7), 2391–2393. -
Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers
Gibbs, I. C., Le, Q. T., Shah, R. D., Terris, D. J., Fee, W. E., & Goffinet, D. R. (2003). Long-term outcomes after external beam irradiation and brachytherapy boost for base-of-tongue cancers. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 57(2), 489–94. -
Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancer
Le, Q. T., & Giaccia, A. J. (2003). Therapeutic exploitation of the physiological and molecular genetic alterations in head and neck cancer. CLINICAL CANCER RESEARCH, 9(12), 4287–95. -
Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer
Koong, A. C., Le, Q. T., Ho, A., Fong, B., Fisher, G., Cho, C., … Bastidas, J. A. (2004). Phase I study of stereotactic radiosurgery in patients with locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 58(4), 1017–21. -
Lens dose in MLC-based IMRT treatments of the head and neck
Pawlicki, T., Luxton, G., Le, Q. T., Findley, D., & Ma, C. M. (2004). Lens dose in MLC-based IMRT treatments of the head and neck. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 59(1), 293–99. -
Extranodal nonorbital indolent lymphomas of the head and neck: Relationship between tumor control and radiotherapy
MacDermed, D., Thurber, L., George, T. I., Hoppe, R. T., & Le, Q. T. (2004). Extranodal nonorbital indolent lymphomas of the head and neck: Relationship between tumor control and radiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. SALT LAKE CITY,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT,UT: ELSEVIER SCIENCE INC. -
Hypoxic gene expression and metastasis
Le, Q. T., Denko, N. C., & Giaccia, A. J. (2004). Hypoxic gene expression and metastasis. CANCER AND METASTASIS REVIEWS, 23(3-4), 293–310. -
Sample classification from protein mass spectrometry, by 'peak probability contrasts'
Tibshirani, R., Hastie, T., Narasimhan, B., Soltys, S., Shi, G. Y., Koong, A., & Le, Q. T. (2004). Sample classification from protein mass spectrometry, by 'peak probability contrasts'. BIOINFORMATICS, 20(17), 3034–44. -
The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers
Soltys, S. G., Le, Q. T., Shi, G. Y., Tibshirani, R., Giaccia, A. J., & Koong, A. C. (2004). The use of plasma surface-enhanced laser desorption/ionization time-of-flight mass spectrometry proteomic patterns for detection of head and neck squamous cell cancers. CLINICAL CANCER RESEARCH, 10(14), 4806–12. -
Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): A Southwest Oncology Group Study
Le, Q. T., McCoy, J., Williamson, S., Ryu, J., Gaspar, L. E., EDELMAN, M. J., … Gandara, D. R. (2004). Phase I study of tirapazamine plus cisplatin/etoposide and concurrent thoracic radiotherapy in limited-stage small cell lung cancer (S0004): A Southwest Oncology Group Study. CLINICAL CANCER RESEARCH, 10(16), 5418–24. -
Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms
Su, C. K., Mehta, V., Ravikumar, L., Shah, R., PINTO, H., Halpern, J., … Le, Q. T. (2004). Phase II double-blind randomized study comparing oral aloe vera versus placebo to prevent radiation-related mucositis in patients with head-and-neck neoplasms. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 60(1), 171–77. -
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
Romero-Ramirez, L., Cao, H. B., Nelson, D., Hammond, E., Lee, A. H., Yoshida, H., … Koong, A. C. (2004). XBP1 is essential for survival under hypoxic conditions and is required for tumor growth. CANCER RESEARCH, 64(17), 5943–47. -
Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling
Chen, Y. J., Shi, G. Y., Wei, X., Kong, C., Zhao, S. C., Gaw, A. F., … Koong, A. C. (2004). Identification of hypoxia-regulated proteins in head and neck cancer by proteomic and tissue array profiling. CANCER RESEARCH, 64(20), 7302–10. -
Long-term results of 100 consecutive comprehensive neck dissections - Implications for selective neck dissections
Sivanandan, R., Kaplan, M. J., Lee, K. J., Lebl, D., PINTO, H., Le, Q. T., … Fee, W. E. (2004). Long-term results of 100 consecutive comprehensive neck dissections - Implications for selective neck dissections. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 130(12), 1369–73. -
Positron-emission tomography for surveillance of head and neck cancer
Ryan, W. R., Fee, W. E., Le, Q. T., & Pinto, H. A. (2005). Positron-emission tomography for surveillance of head and neck cancer. LARYNGOSCOPE, 115(4), 645–50. -
Nonsurgical therapy for stages I and II non-small cell lung cancer
Le, Q. T., & Petrik, D. W. (2005). Nonsurgical therapy for stages I and II non-small cell lung cancer. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA, 19(2), 237-? -
Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a ras-activated enhancer
Zhu, Y. H., Denhardt, D. T., Cao, H. B., Sutphin, P. D., Koong, A. C., Giaccia, A. J., & Le, Q. T. (2005). Hypoxia upregulates osteopontin expression in NIH-3T3 cells via a ras-activated enhancer. ONCOGENE, 24(43), 6555–63. -
A noninvasive approach for assessing tumor hypoxia in xenografts: Developing a urinary marker for hypoxia
Nelson, D. W., Cao, H. B., Zhu, Y. H., Sunar-Reeder, B., Choi, C. Y. H., Faix, J. D., … Le, Q. T. (2005). A noninvasive approach for assessing tumor hypoxia in xenografts: Developing a urinary marker for hypoxia. CANCER RESEARCH, 65(14), 6151–58. -
A comparison study of different PCR assays in measuring circulating plasma Epstein-Barr virus DNA levels in patients with nasopharyngeal carcinoma
Le, Q. T., Jones, C. D., Yau, T. K., Shirazi, H. A., Wong, P. H., Thomas, E. N., … Zehnder, J. L. (2005). A comparison study of different PCR assays in measuring circulating plasma Epstein-Barr virus DNA levels in patients with nasopharyngeal carcinoma. CLINICAL CANCER RESEARCH, 11(16), 5700–5707. -
Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer
Koong, A. C., Christofferson, E., Le, Q. T., Goodman, K. A., Ho, A., Kuo, T., … Yang, G. P. (2005). Phase II study to assess the efficacy of conventionally fractionated radiotherapy followed by a stereotactic radiosurgery boost in patients with locally advanced pancreatic cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 63(2), 320–23. -
Galectin-1: A link between tumor hypoxia and tumor immune privilege
Le, Q. T., Shi, G. Y., Cao, H. B., Nelson, D. W., Wang, Y. Y., CHEN, E. Y., … Koong, A. C. (2005). Galectin-1: A link between tumor hypoxia and tumor immune privilege. JOURNAL OF CLINICAL ONCOLOGY. ATLANTA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA,GA: AMER SOC CLINICAL ONCOLOGY. -
Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae
Chen, Y. J., Feldman, D. E., Deng, C. C., BROWN, J. A., De Giacomo, A. F., Gaw, A. F., … Koong, A. C. (2005). Identification of mitogen-activated protein kinase signaling pathways that confer resistance to endoplasmic reticulum stress in Saccharomyces cerevisiae. MOLECULAR CANCER RESEARCH, 3(12), 669–77. -
Comment on: Osteopontin as toxic marker
Le, Q. T., Cao, H. B., & Giaccia, A. (2006). Comment on: Osteopontin as toxic marker. RADIOTHERAPY AND ONCOLOGY, 78(2), 230–230. -
Image-guided radiosurgery in the treatment of spinal metastases.
MURPHY, M. J., Chang, S., Gibbs, I., Le, Q. T., Martin, D., & Kim, D. (2001). Image-guided radiosurgery in the treatment of spinal metastases. Neurosurgical Focus, 11(6). -
Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site
Shirazi, H. A., Sivanandan, R., Goode, R., Fee, W. E., Kaplan, M. J., Pinto, H. A., … Le, Q.-T. (2006). Advanced-staged tonsillar squamous carcinoma: Organ preservation versus surgical management of the primary site. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 28(7), 587–94. -
Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV head and neck squamous cell carcinomas
Le, Q. T., Taira, A. I., Budenz, S., Dorie, M. J., Goffinet, D. R., Fee, W. E., … Pinto, H. A. (2006). Mature results from a randomized phase II trial of cisplatin plus 5-fluorouracil and radiotherapy with or without tirapazamine in patients with resectable stage IV head and neck squamous cell carcinomas. CANCER, 106(9), 1940–49. -
An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers
Le, Q. T., Chen, E., Salim, A., Cao, H. B., Kong, C. S., Whyte, R., … Giaccia, A. J. (2006). An evaluation of tumor oxygenation and gene expression in patients with early stage non-small cell lung cancers. CLINICAL CANCER RESEARCH, 12(5), 1507–14. -
Lysyl oxidase is essential for hypoxia-induced metastasis
Erler, J. T., Bennewith, K. L., Nicolau, M., Dornhofer, N., Kong, C., Le, Q. T., … Giaccia, A. J. (2006). Lysyl oxidase is essential for hypoxia-induced metastasis. NATURE, 440(7088), 1222–26. -
Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis
Dornhoefer, N., Spong, S., Bennewith, K., Salim, A., Klaus, S., Kambham, N., … Giaccia, A. (2006). Connective tissue growth factor-specific monoclonal antibody therapy inhibits pancreatic tumor growth and metastasis. CANCER RESEARCH, 66(11), 5816–27. -
Lung cancer in women: Exploring sex differences in susceptibility, biology, and therapeutic response
Donington, J. S., Le, Q.-T., & Wakelee, H. A. (2006). Lung cancer in women: Exploring sex differences in susceptibility, biology, and therapeutic response. CLINICAL LUNG CANCER, 8(1), 22–29. -
Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: A pilot study in humans
Loo, B. W., Draney, M. T., Sivanandan, R., Ruehm, S. G., Pawlicki, T., Xing, L., … Le, Q.-T. (2006). Indirect MR lymphangiography of the head and neck using conventional gadolinium contrast: A pilot study in humans. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 66(2), 462–68. -
A multidisciplinary approach to management in a patient with bilateral superior sulcus non-small-cell lung carcinoma
Roy, M. S., Le, Q.-T., Donington, J. S., & Wakelee, H. A. (2006). A multidisciplinary approach to management in a patient with bilateral superior sulcus non-small-cell lung carcinoma. CLINICAL LUNG CANCER, 8(2), 146–48. -
Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma
Daly, M. E., Lieskovsky, Y. Y., Pawlicki, T., Yau, J., Pinto, H., Kaplan, M., … Le, Q.-T. (2007). Evaluation of patterns of failure and subjective salivary function in patients treated with intensity modulated radiotherapy for head and neck squamous cell carcinoma. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 29(3), 211–20. -
Plasma osteopontin is an independent prognostic marker for head and neck cancers
Petrik, D., Lavori, P. W., Cao, H., Zhu, Y., Wong, P., Christofferson, E., … Le, Q.-T. (2006). Plasma osteopontin is an independent prognostic marker for head and neck cancers. JOURNAL OF CLINICAL ONCOLOGY, 24(33), 5291–97. -
Clinical role of F-18-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma
Quon, A., Fischbein, N. J., McDougall, I. R., Le, Q.-T., Loo, B. W., Pinto, H., & Kaplan, M. J. (2007). Clinical role of F-18-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma. JOURNAL OF NUCLEAR MEDICINE, 48, 58S–67S. -
Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors
Le, Q.-T., Loo, B. W., Ho, A., Cotrutz, C., Koong, A. C., Wakelee, H., … Donington, J. (2006). Results of a phase I dose-escalation study using single-fraction stereotactic radiotherapy for lung tumors. JOURNAL OF THORACIC ONCOLOGY, 1(8), 802–9. -
Nasopharyngeal and oropharyngeal carcinomas: Target delineation, therapy delivery and stereotactic boost procedures with intensity-modulated/image-guided radiation therapy
Le, Q.-T. (2007). Nasopharyngeal and oropharyngeal carcinomas: Target delineation, therapy delivery and stereotactic boost procedures with intensity-modulated/image-guided radiation therapy. Presented at the 38th San Francisco Radiation Oncology Conference, SAN FRANCISCO,CA,CA,CA,CA,CA,CA: KARGER. -
Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas
Le, Q.-T., Kong, C., Lavori, P. W., O'Byrne, K., Erler, J. T., Huang, X., … Koong, A. C. (2007). Expression and prognostic significance of a panel of tissue hypoxia markers in head-and-neck squamous cell carcinomas. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(1), 167–75. -
Identifying and targeting hypoxia in head and neck cancer: A brief overview of current approaches
Le, Q.-T. (2007). Identifying and targeting hypoxia in head and neck cancer: A brief overview of current approaches. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(2), S56–S58. -
Quantification of motion of different thoracic locations using four-dimensional computed tomography: Implications for radiotherapy planning
Maxim, P. G., Loo, B. W., Shirazi, H., Thorndyke, B., Luxton, G., & Le, Q.-T. (2007). Quantification of motion of different thoracic locations using four-dimensional computed tomography: Implications for radiotherapy planning. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(5), 1395–1401. -
Metabolic tumor burden predicts for disease progression and death in lung cancer
Lee, P., Weerasuriya, D. K., Lavori, P. W., Quon, A., Hara, W., Maxim, P. G., … Loo, B. W. (2007). Metabolic tumor burden predicts for disease progression and death in lung cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 69(2), 328–33. -
Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma
Hara, W., Loo, B. W., Goffinet, D. R., Chang, S. D., Adler, J. R., Pinto, H. A., … Le, Q.-T. (2008). Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 71(2), 393–400. -
Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file
Lee, L., Le, Q.-T., & Xing, L. (2008). Retrospective IMRT dose reconstruction based on cone-beam CT and MLC log-file. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 70(2), 634–44. -
In vivo H-1 magnetic resonance spectroscopy of lactate in patients with Stage IV head and neck squamous cell carcinoma
Le, Q.-T., Koong, A., Lieskovsky, Y. Y., Narasimhan, B., Graves, E., Pinto, H., … Spielman, D. (2008). In vivo H-1 magnetic resonance spectroscopy of lactate in patients with Stage IV head and neck squamous cell carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 71(4), 1151–57. -
LINAC-based on-board imaging feasibility and the dosimetric consequences of head roll in head-and-neck IMRT plans
Kim, G.-Y., Pawlicki, T., Le, Q.-T., & Luxton, G. (2008). LINAC-based on-board imaging feasibility and the dosimetric consequences of head roll in head-and-neck IMRT plans. MEDICAL DOSIMETRY, 33(1), 93–99. -
Clinical biomarkers for hypoxia targeting
Le, Q.-T., & Courter, D. (2008). Clinical biomarkers for hypoxia targeting. CANCER AND METASTASIS REVIEWS, 27(3), 351–62. -
Lower osteopontin plasma levels are associated with superior outcomes in advanced non-small-cell lung cancer patients receiving platinum-based chemotherapy: SWOG study S0003
Mack, P. C., Redman, M. W., Chansky, K., Williamson, S. K., Farneth, N. C., Lara, P. N., … Gandara, D. R. (2008). Lower osteopontin plasma levels are associated with superior outcomes in advanced non-small-cell lung cancer patients receiving platinum-based chemotherapy: SWOG study S0003. JOURNAL OF CLINICAL ONCOLOGY, 26(29), 4771–4776. -
Integrating Biologically Targeted Therapy in Head and Neck Squamous Cell Carcinomas
Le, Q.-T., & Rabent, D. (2009). Integrating Biologically Targeted Therapy in Head and Neck Squamous Cell Carcinomas. SEMINARS IN RADIATION ONCOLOGY, 19(1), 53–62. -
Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche
Erler, J. T., Bennewith, K. L., Cox, T. R., Lang, G., Bird, D., Koong, A., … Giaccia, A. J. (2009). Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche. CANCER CELL, 15(1), 35–44. -
Molecular Imaging of Hypoxia-Inducible Factor 1 alpha and von Hippel-Lindau Interaction in Mice
Choi, C. Y. H., Chau, D. A., Paulmurugan, R., Sutphin, P. D., Le, Q.-T., Koong, A. C., … Giaccia, A. J. (2008). Molecular Imaging of Hypoxia-Inducible Factor 1 alpha and von Hippel-Lindau Interaction in Mice. MOLECULAR IMAGING, 7(3), 139–46. -
X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas.
Romero-Ramirez, L., Cao, H., Regalado, M. P., Kambham, N., Siemann, D., Kim, J. J., … Koong, A. C. (2009). X box-binding protein 1 regulates angiogenesis in human pancreatic adenocarcinomas. Translational Oncology, 2(1), 31–38. -
METABOLIC TUMOR VOLUME PREDICTS FOR RECURRENCE AND DEATH IN HEAD-AND-NECK CANCER
La, T. H., Filion, E. J., Turnbull, B. B., Chu, J. N., Lee, P., Nguyen, K., … Le, Q.-T. (2009). METABOLIC TUMOR VOLUME PREDICTS FOR RECURRENCE AND DEATH IN HEAD-AND-NECK CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 74(5), 1335–41. -
COMPARISON OF TREATMENT RESULTS BETWEEN ADULT AND JUVENILE NASOPHARYNGEAL CARCINOMA
Downing, N. L., Wolden, S., Wong, P., Petrik, D. W., Hara, W., & Le, Q.-T. (2009). COMPARISON OF TREATMENT RESULTS BETWEEN ADULT AND JUVENILE NASOPHARYNGEAL CARCINOMA. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 75(4), 1064–70. -
THE RELATIONSHIP BETWEEN HUMAN PAPILLOMAVIRUS STATUS AND OTHER MOLECULAR PROGNOSTIC MARKERS IN HEAD AND NECK SQUAMOUS CELL CARCINOMAS
Kong, C. S., Narasimhan, B., Cao, H., Kwok, S., Erickson, J. P., Koong, A., … Le, Q.-T. (2009). THE RELATIONSHIP BETWEEN HUMAN PAPILLOMAVIRUS STATUS AND OTHER MOLECULAR PROGNOSTIC MARKERS IN HEAD AND NECK SQUAMOUS CELL CARCINOMAS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 74(2), 553–61. -
PET of EGFR Antibody Distribution in Head and Neck Squamous Cell Carcinoma Models
Niu, G., Li, Z., Xie, J., Le, Q.-T., & Chen, X. (2009). PET of EGFR Antibody Distribution in Head and Neck Squamous Cell Carcinoma Models. JOURNAL OF NUCLEAR MEDICINE, 50(7), 1116–23. -
INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF OROPHARYNGEAL CANCER: CLINICAL OUTCOMES AND PATTERNS OF FAILURE
Daly, M. E., Le, Q.-T., Maxim, P. G., Loo, B. W., Kaplan, M. J., Fischbein, N. J., … Chang, D. T. (2010). INTENSITY-MODULATED RADIOTHERAPY IN THE TREATMENT OF OROPHARYNGEAL CANCER: CLINICAL OUTCOMES AND PATTERNS OF FAILURE. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 76(5), 1339–46. -
Mucositis-Related Morbidity and Resource Utilization in Head and Neck Cancer Patients Receiving Radiation Therapy With or Without Chemotherapy
Murphy, B. A., Beaumont, J. L., Isitt, J., Garden, A. S., Gwede, C. K., Trotti, A. M., … Cella, D. (2009). Mucositis-Related Morbidity and Resource Utilization in Head and Neck Cancer Patients Receiving Radiation Therapy With or Without Chemotherapy. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 38(4), 522–532. -
Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03
Le, Q.-T., Harris, J., Magliocco, A. M., Kong, C. S., Diaz, R., Shin, B., … Ang, K. K. (2009). Validation of Lysyl Oxidase As a Prognostic Marker for Metastasis and Survival in Head and Neck Squamous Cell Carcinoma: Radiation Therapy Oncology Group Trial 90-03. JOURNAL OF CLINICAL ONCOLOGY, 27(26), 4281–86. -
Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation
Huang, X., Ding, L., Bennewith, K. L., Tong, R. T., Welford, S. M., Ang, K. K., … Giaccia, A. J. (2009). Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation. MOLECULAR CELL, 35(6), 856–67. -
Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis
Chang, S. T., Zahn, J. M., Horecka, J., Kunz, P. L., Ford, J. M., Fisher, G. A., … Koong, A. C. (2009). Identification of a biomarker panel using a multiplex proximity ligation assay improves accuracy of pancreatic cancer diagnosis. JOURNAL OF TRANSLATIONAL MEDICINE, 7. -
Imaging the Unfolded Protein Response in Primary Tumors Reveals Microenvironments with Metabolic Variations that Predict Tumor Growth
Spiotto, M. T., Banh, A., Papandreou, I., Cao, H., Galvez, M. G., Gurtner, G. C., … Koong, A. C. (2010). Imaging the Unfolded Protein Response in Primary Tumors Reveals Microenvironments with Metabolic Variations that Predict Tumor Growth. CANCER RESEARCH, 70(1), 78–88. -
HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA
Filion, E. J., McClure, L. A., Huang, D., Seng, K., Kaplan, M. J., Colevas, A. D., … Le, Q.-T. (2010). HIGHER INCIDENCE OF HEAD AND NECK CANCERS AMONG VIETNAMESE AMERICAN MEN IN CALIFORNIA. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 32(10), 1336–44. -
Cetuximab-Based Immunotherapy and Radioimmunotherapy of Head and Neck Squamous Cell Carcinoma
Niu, G., Sun, X., Cao, Q., Courter, D., Koong, A., Le, Q.-T., … Chen, X. (2010). Cetuximab-Based Immunotherapy and Radioimmunotherapy of Head and Neck Squamous Cell Carcinoma. CLINICAL CANCER RESEARCH, 16(7), 2095–2105. -
The RGD Domain of Human Osteopontin Promotes Tumor Growth and Metastasis through Activation of Survival Pathways
Courter, D., Cao, H., Kwok, S., Kong, C., Banh, A., Kuo, P., … Le, Q.-T. (2010). The RGD Domain of Human Osteopontin Promotes Tumor Growth and Metastasis through Activation of Survival Pathways. PLOS ONE, 5(3). -
Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer
Ho, A. S., Huang, X., Cao, H., Christman-Skieller, C., Bennewith, K., Le, Q.-T., & Koong, A. C. (2010). Circulating miR-210 as a Novel Hypoxia Marker in Pancreatic Cancer. TRANSLATIONAL ONCOLOGY, 3(2), 109–13. -
MiR-210-micromanager of the hypoxia pathway
Huang, X., Le, Q.-T., & Giaccia, A. J. (2010). MiR-210-micromanager of the hypoxia pathway. TRENDS IN MOLECULAR MEDICINE, 16(5), 230–37. -
Dose reconstruction for volumetric modulated arc therapy (VMAT) using cone-beam CT and dynamic log files
Qian, J., Lee, L., Liu, W., Chu, K., Mok, E., Luxton, G., … Xing, L. (2010). Dose reconstruction for volumetric modulated arc therapy (VMAT) using cone-beam CT and dynamic log files. PHYSICS IN MEDICINE AND BIOLOGY, 55(13), 3597–3610. -
Image-based modeling of tumor shrinkage in head and neck radiation therapy
Chao, M., Xie, Y., Moros, E. G., Le, Q.-T., & Xing, L. (2010). Image-based modeling of tumor shrinkage in head and neck radiation therapy. MEDICAL PHYSICS, 37(5), 2351–58. -
POSTRADIATION METABOLIC TUMOR VOLUME PREDICTS OUTCOME IN HEAD-AND-NECK CANCER
Murphy, J. D., La, T. H., Chu, K., Quon, A., Fischbein, N. J., Maxim, P. G., … Le, Q.-T. (2011). POSTRADIATION METABOLIC TUMOR VOLUME PREDICTS OUTCOME IN HEAD-AND-NECK CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 80(2), 514–21. -
HIGH RETENTION AND SAFETY OF PERCUTANEOUSLY IMPLANTED ENDOVASCULAR EMBOLIZATION COILS AS FIDUCIAL MARKERS FOR IMAGE-GUIDED STEREOTACTIC ABLATIVE RADIOTHERAPY OF PULMONARY TUMORS
Hong, J. C., Yu, Y., Rao, A. K., Ditererich, S., Maxim, P. G., Le, Q.-T., … Loo, B. W. (2011). HIGH RETENTION AND SAFETY OF PERCUTANEOUSLY IMPLANTED ENDOVASCULAR EMBOLIZATION COILS AS FIDUCIAL MARKERS FOR IMAGE-GUIDED STEREOTACTIC ABLATIVE RADIOTHERAPY OF PULMONARY TUMORS. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(1), 85–90. -
INTENSITY-MODULATED RADIOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA: PATTERNS OF FAILURE AND PREDICTORS OF LOCAL CONTROL
Daly, M. E., Quynh-Thu Le, Q. T., Kozak, M. M., Maxim, P. G., Murphy, J. D., Hsu, A., … Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR ORAL CAVITY SQUAMOUS CELL CARCINOMA: PATTERNS OF FAILURE AND PREDICTORS OF LOCAL CONTROL. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 80(5), 1412–22. -
The Tumor Microenvironment in Non-Small-Cell Lung Cancer
Graves, E. E., Maity, A., & Le, Q.-T. (2010). The Tumor Microenvironment in Non-Small-Cell Lung Cancer. SEMINARS IN RADIATION ONCOLOGY, 20(3), 156–63. -
Prognostic Significance of p16(INK4A) and Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial
Rischin, D., Young, R. J., Fisher, R., Fox, S. B., Le, Q.-T., Peters, L. J., … McArthur, G. A. (2010). Prognostic Significance of p16(INK4A) and Human Papillomavirus in Patients With Oropharyngeal Cancer Treated on TROG 02.02 Phase III Trial. JOURNAL OF CLINICAL ONCOLOGY. ORLANDO,FL,FL,FL,FL,FL: AMER SOC CLINICAL ONCOLOGY. -
INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX
Daly, M. E., Le, Q.-T., Jain, A. K., Maxim, P. G., Hsu, A., Loo, B. W., … Chang, D. T. (2011). INTENSITY-MODULATED RADIOTHERAPY FOR LOCALLY ADVANCED CANCERS OF THE LARYNX AND HYPOPHARYNX. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 33(1), 103–11. -
Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics
Graves, E. E., Vilalta, M., Cecic, I. K., Erler, J. T., Tran, P. T., Felsher, D., … Giaccia, A. J. (2010). Hypoxia in Models of Lung Cancer: Implications for Targeted Therapeutics. CLINICAL CANCER RESEARCH, 16(19), 4843–52. -
MYB Expression and Translocation in Adenoid Cystic Carcinomas and Other Salivary Gland Tumors With Clinicopathologic Correlation
West, R. B., Kong, C., Clarke, N., Gilks, T., Lipsick, J. S., Cao, H., … Le, Q.-T. (2011). MYB Expression and Translocation in Adenoid Cystic Carcinomas and Other Salivary Gland Tumors With Clinicopathologic Correlation. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 35(1), 92–99. -
Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003)
Chung, C. H., Dignam, J. J., Hammond, M. E., Klimowicz, A. C., Petrillo, S. K., Magliocco, A., … Ang, K. K. (2011). Glioma-Associated Oncogene Family Zinc Finger 1 Expression and Metastasis in Patients With Head and Neck Squamous Cell Carcinoma Treated With Radiation Therapy (RTOG 9003). JOURNAL OF CLINICAL ONCOLOGY, 29(10), 1326–1333. -
Head and Neck Cancer-Specific Survival Based on Socioeconomic Status in Asians and Pacific Islanders
Chu, K. P., Shema, S., Wu, S., Gomez, S. L., Chang, E. T., & Quynh-Thu Le, Q. T. (2011). Head and Neck Cancer-Specific Survival Based on Socioeconomic Status in Asians and Pacific Islanders. CANCER, 117(9), 1935–45. -
ON-BOARD IMAGING VALIDATION OF OPTICALLY GUIDED STEREOTACTIC RADIOSURGERY POSITIONING SYSTEM FOR CONVENTIONALLY FRACTIONATED RADIOTHERAPY FOR PARANASAL SINUS AND SKULL BASE CANCER
Maxim, P. G., Loo, B. W., Murphy, J. D., Chu, K. P. M., Hsu, A., & Quynh-Thu Le, Q. T. (2011). ON-BOARD IMAGING VALIDATION OF OPTICALLY GUIDED STEREOTACTIC RADIOSURGERY POSITIONING SYSTEM FOR CONVENTIONALLY FRACTIONATED RADIOTHERAPY FOR PARANASAL SINUS AND SKULL BASE CANCER. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(4), 1153–59. -
Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis
Banh, A., Zhang, J., Cao, H., Bouley, D. M., Kwok, S., Kong, C., … Le, Q.-T. (2011). Tumor Galectin-1 Mediates Tumor Growth and Metastasis through Regulation of T-Cell Apoptosis. CANCER RESEARCH, 71(13), 4423–31. -
Intensity-Modulated and Image-Guided Radiation Therapy for Head and Neck Cancers
Chu, K. P.-M., & Le, Q.-T. (2011). Intensity-Modulated and Image-Guided Radiation Therapy for Head and Neck Cancers. IMRT IGRT SBRT- ADVANCES IN THE TREATMENT PLANNING AND DELIVERY OF RADIOTHERAPY, 43, 217–54. -
Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity
Murphy, J. D., Chisholm, K. M., Daly, M. E., Wiegner, E. A., Truong, D., Iagaru, A., … Le, Q.-T. (2011). Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity. RADIOTHERAPY AND ONCOLOGY, 101(3), 356–61. -
Palifermin Reduces Severe Mucositis in Definitive Chemoradiotherapy of Locally Advanced Head and Neck Cancer: A Randomized, Placebo-Controlled Study
Le, Q.-T., Kim, H. E., Schneider, C. J., Murakozy, G., Skladowski, K., Reinisch, S., … Henke, M. (2011). Palifermin Reduces Severe Mucositis in Definitive Chemoradiotherapy of Locally Advanced Head and Neck Cancer: A Randomized, Placebo-Controlled Study. JOURNAL OF CLINICAL ONCOLOGY, 29(20), 2808–14. -
Metabolic Tumor Volume is an Independent Prognostic Factor in Patients Treated Definitively for Non-Small-Cell Lung Cancer
Lee, P., Bazan, J. G., Lavori, P. W., Weerasuriya, D. K., Quon, A., Quynh-Thu Le, Q. T., … Loo, B. W. (2012). Metabolic Tumor Volume is an Independent Prognostic Factor in Patients Treated Definitively for Non-Small-Cell Lung Cancer. CLINICAL LUNG CANCER, 13(1), 52–58. -
Results from a Single Institution Phase II Trial of Concurrent Docetaxel/Carboplatin/Radiotherapy Followed by Surgical Resection and Consolidation Docetaxel/Carboplatin in Stage III Non-Small-Cell Lung Cancer
Das, M., Donington, J. S., Murphy, J., Kozak, M., Eclov, N., Whyte, R. I., … Wakelee, H. (2011). Results from a Single Institution Phase II Trial of Concurrent Docetaxel/Carboplatin/Radiotherapy Followed by Surgical Resection and Consolidation Docetaxel/Carboplatin in Stage III Non-Small-Cell Lung Cancer. CLINICAL LUNG CANCER, 12(5), 280–85. -
Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer
Kozak, M. M., Murphy, J. D., Schipper, M. L., Donington, J. S., Zhou, L., Whyte, R. I., … Loo, B. W. (2011). Tumor Volume as a Potential Imaging-Based Risk-Stratification Factor in Trimodality Therapy for Locally Advanced Non-small Cell Lung Cancer. JOURNAL OF THORACIC ONCOLOGY, 6(5), 920–26. -
Quantitation of Human Papillomavirus DNA in Plasma of Oropharyngeal Carcinoma Patients
Cao, H., Banh, A., Kwok, S., Shi, X., Wu, S., Krakow, T., … Quynh-Thu Le, Q. T. (2012). Quantitation of Human Papillomavirus DNA in Plasma of Oropharyngeal Carcinoma Patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 82(3), E351–E358. -
A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo
Banh, A., Xiao, N., Cao, H., Chen, C.-H., Kuo, P., Krakow, T., … Quynh-Thu Le, Q. T. (2011). A Novel Aldehyde Dehydrogenase-3 Activator Leads to Adult Salivary Stem Cell Enrichment In Vivo. CLINICAL CANCER RESEARCH, 17(23), 7265–72. -
Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure
Wiegner, E. A., Daly, M. E., Murphy, J. D., Abelson, J., Chapman, C. H., Chung, M., … Chang, D. T. (2012). Intensity-Modulated Radiotherapy for Tumors of the Nasal Cavity and Paranasal Sinuses: Clinical Outcomes and Patterns of Failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. SAN DIEGO,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA,CA: ELSEVIER SCIENCE INC. -
Prognostic Significance of Plasma Osteopontin in Patients with Locoregionally Advanced Head and Neck Squamous Cell Carcinoma Treated on TROG 02.02 Phase III Trial
Lim, A. M., Rischin, D., Fisher, R., Cao, H., Kwok, K., Truong, D., … Le, Q.-T. (2012). Prognostic Significance of Plasma Osteopontin in Patients with Locoregionally Advanced Head and Neck Squamous Cell Carcinoma Treated on TROG 02.02 Phase III Trial. CLINICAL CANCER RESEARCH, 18(1), 301–7. -
A Planned Neck Dissection Is Not Necessary in All Patients With N2-3 Head-and-Neck Cancer After Sequential Chemoradiotherapy
Soltys, S. G., Choi, C. Y. H., Fee, W. E., Pinto, H. A., & Le, Q.-T. (2012). A Planned Neck Dissection Is Not Necessary in All Patients With N2-3 Head-and-Neck Cancer After Sequential Chemoradiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(3), 994–99. -
Esophageal tolerance to high-dose stereotactic ablative radiotherapy
Abelson, J. A., Murphy, J. D., Loo, B. W., Chang, D. T., Daly, M. E., Wiegner, E. A., … Gibbs, I. C. (2012). Esophageal tolerance to high-dose stereotactic ablative radiotherapy. DISEASES OF THE ESOPHAGUS, 25(7), 623–29. -
Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial
Lee, N. Y., Zhang, Q., Pfister, D. G., Kim, J., Garden, A. S., Mechalakos, J., … Ang, K. K. (2012). Addition of bevacizumab to standard chemoradiation for locoregionally advanced nasopharyngeal carcinoma (RTOG 0615): a phase 2 multi-institutional trial. LANCET ONCOLOGY, 13(2), 172–80. -
Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head-and-Neck Cancer Outcomes
Chu, K. P., Murphy, J. D., La, T. H., Krakow, T. E., Iagaru, A., Graves, E. E., … Quynh-Thu Le, Q. T. (2012). Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head-and-Neck Cancer Outcomes. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), 1521–27. -
Validation that metabolic tumor volume predicts outcome in head-and-neck cancer.
Tang, C., Murphy, J. D., Khong, B., La, T. H., Kong, C., Fischbein, N. J., … Le, Q.-T. (2012). Validation that metabolic tumor volume predicts outcome in head-and-neck cancer. International Journal of Radiation Oncology, Biology, Physics, 83(5), 1514–20. -
Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors
Trakul, N., Chang, C. N., Harris, J., Chapman, C., Rao, A., Shen, J., … Diehn, M. (2012). Tumor Volume-Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(1), 231–37. -
Prognostic and Predictive Significance of Plasma HGF and IL-8 in a Phase III Trial of Chemoradiation with or without Tirapazamine in Locoregionally Advanced Head and Neck Cancer
Quynh-Thu Le, Q. T., Fisher, R., Oliner, K. S., Young, R. J., Cao, H., Kong, C., … Rischin, D. (2012). Prognostic and Predictive Significance of Plasma HGF and IL-8 in a Phase III Trial of Chemoradiation with or without Tirapazamine in Locoregionally Advanced Head and Neck Cancer. CLINICAL CANCER RESEARCH, 18(6), 1798–1807. -
Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck.
Tang, C., Fischbein, N. J., Murphy, J. D., Chu, K. P., Bavan, B., Dieterich, S., … Le, Q.-T. (2013). Stereotactic radiosurgery for retreatment of gross perineural invasion in recurrent cutaneous squamous cell carcinoma of the head and neck. American Journal of Clinical Oncology, 36(3), 293–98. -
Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images
Li, R., Mok, E., Chang, D. T., Daly, M., Loo, B. W., Diehn, M., … Xing, L. (2012). Intrafraction Verification of Gated RapidArc by Using Beam-Level Kilovoltage X-Ray Images. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 83(5), E709–E715. -
Evaluation of ProExC as a Prognostic Marker in Oropharyngeal Squamous Cell Carcinomas
Mills, A. M., Beck, A. H., Pourmand, N., Quynh Thu Le, Q. T., & Kong, C. S. (2012). Evaluation of ProExC as a Prognostic Marker in Oropharyngeal Squamous Cell Carcinomas. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 36(8), 1158–64. -
CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma
Janisiewicz, A. M., Shin, J. H., Murillo-Sauca, O., Kwok, S., Quynh-Thu Le, Q. T., Kong, C., … Sunwoo, J. B. (2012). CD44+cells have cancer stem cell-like properties in nasopharyngeal carcinoma. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY, 2(6), 465–70. -
Stereotactic Ablative Radiotherapy for Reirradiation of Locally Recurrent Lung Tumors
Trakul, N., Harris, J. P., Le, Q.-T., Hara, W. Y., Maxim, P. G., Loo, B. W., & Diehn, M. (2012). Stereotactic Ablative Radiotherapy for Reirradiation of Locally Recurrent Lung Tumors. JOURNAL OF THORACIC ONCOLOGY, 7(9), 1462–65. -
Volumetric-modulated arc radiotherapy for skull-base and non-skull-base head and neck cancer: a treatment planning comparison with fixed Beam IMRT.
Chen, J., Mok, E., Wang, L., Chen, C., & Le, Q. (2013). Volumetric-modulated arc radiotherapy for skull-base and non-skull-base head and neck cancer: a treatment planning comparison with fixed Beam IMRT. Technology in Cancer Research & Treatment, 12(1), 11–18. -
Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy.
Abelson, J. A., Murphy, J. D., Trakul, N., Bazan, J. G., Maxim, P. G., Graves, E. E., … Loo, B. W. (2012). Metabolic imaging metrics correlate with survival in early stage lung cancer treated with stereotactic ablative radiotherapy. Lung Cancer , 78(3), 219–24. -
Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse.
Kong, C. S., Cao, H., Kwok, S., Nguyen, C. M., Jordan, R. C., Beaudry, V. G., … Le, Q.-T. (2013). Loss of the p53/p63 target PERP is an early event in oral carcinogenesis and correlates with higher rate of local relapse. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 115(1), 95–103. -
Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence.
Ho, A. S., Tsao, G. J., Chen, F. W., Shen, T., Kaplan, M. J., Colevas, A. D., … Yao, M. (2013). Impact of positron emission tomography/computed tomography surveillance at 12 and 24 months for detecting head and neck cancer recurrence. Cancer, 119(7), 1349–56. -
Salvage Treatment for Locally Recurrent Nasopharyngeal Carcinoma (NPC).
Chen, C., Fee, W., Chen, J., Chan, C., Khong, B., Hara, W., … Le, Q.-T. (2014). Salvage Treatment for Locally Recurrent Nasopharyngeal Carcinoma (NPC). American Journal of Clinical Oncology, 37(4), 327–31. -
An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma.
Le, Q.-T., Zhang, Q., Cao, H., Cheng, A.-J., Pinsky, B. A., Hong, R.-L., … Chan, K. C. A. (2013). An international collaboration to harmonize the quantitative plasma Epstein-Barr virus DNA assay for future biomarker-guided trials in nasopharyngeal carcinoma. Clinical Cancer Research , 19(8), 2208–15. -
Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy.
Hong, J. C., Eclov, N. C. W., Yu, Y., Rao, A. K., Dieterich, S., Le, Q.-T., … Maxim, P. G. (2013). Migration of implanted markers for image-guided lung tumor stereotactic ablative radiotherapy. Journal of Applied Clinical Medical Physics , 14(2), 4046-? -
Opportunities and challenges in the era of molecularly targeted agents and radiation therapy.
Lin, S. H., George, T. J., Ben-Josef, E., Bradley, J., Choe, K. S., Edelman, M. J., … Chung, C. H. (2013). Opportunities and challenges in the era of molecularly targeted agents and radiation therapy. Journal of the National Cancer Institute, 105(10), 686–93. -
Long-Term Outcomes of Surgery Followed by Radiation Therapy for Minor Salivary Gland Carcinomas
Zeidan, Y. H., Shultz, D. B., Murphy, J. D., Chan, C., Kaplan, M. J., Colevas, A. D., … Le, Q.-T. (2013). Long-Term Outcomes of Surgery Followed by Radiation Therapy for Minor Salivary Gland Carcinomas. LARYNGOSCOPE, 123(11), 2675–80. -
Radiotherapy for nonadenoid cystic carcinomas of major salivary glands.
Chung, M. P., Tang, C., Chan, C., Hara, W. Y., Loo, B. W., Kaplan, M. J., … Chang, D. T. (2013). Radiotherapy for nonadenoid cystic carcinomas of major salivary glands. American Journal of Otolaryngology, 34(5), 425–30. -
Human papillomavirus 16 detected in nasopharyngeal carcinomas in white Americans but not in endemic Southern Chinese patients.
Lin, Z., Khong, B., Kwok, S., Cao, H., West, R. B., Le, Q.-T., & Kong, C. S. (2014). Human papillomavirus 16 detected in nasopharyngeal carcinomas in white Americans but not in endemic Southern Chinese patients. Head & Neck, 36(5), 709–14. -
Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy.
Sasportas, L. S., Hosford, D. N., Sodini, M. A., Waters, D. J., Zambricki, E. A., Barral, J. K., … Sirjani, D. (2013). Cost-effectiveness landscape analysis of treatments addressing xerostomia in patients receiving head and neck radiation therapy. Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, 116(1), e37–51. -
Low-dose radiation therapy (2 Gy × 2) in the treatment of orbital lymphoma.
Fasola, C. E., Jones, J. C., Huang, D. D., Le, Q.-T., Hoppe, R. T., & Donaldson, S. S. (2013). Low-dose radiation therapy (2 Gy × 2) in the treatment of orbital lymphoma. International Journal of Radiation Oncology, Biology, Physics, 86(5), 930–35. -
PATTERN OF RECURRENCE OF MEDULLOBLASTOMA AFTER LOW-DOSE CRANIOSPINAL RADIOTHERAPY
Wara, W. M., LE, Q. T. X., Sneed, P. K., Larson, D. A., Prados, M. D., Levin, V. A., … Weil, M. D. (1994). PATTERN OF RECURRENCE OF MEDULLOBLASTOMA AFTER LOW-DOSE CRANIOSPINAL RADIOTHERAPY. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 30(3), 551–556. -
Prognostic factors in adult soft-tissue sarcomas of the head and neck
LE, Q. T. X., Fu, K. K., KROLL, S., Fitts, L., Massullo, V., Ferrell, L., … Phillips, T. L. (1997). Prognostic factors in adult soft-tissue sarcomas of the head and neck. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 37(5), 975–984. -
Adult medulloblastoma: An analysis of survival and prognostic factors
Le, Q. T., Weil, M. D., Wara, W. M., Lamborn, K. R., Prados, M. D., Edwards, M. S. B., & Gutin, P. H. (1997). Adult medulloblastoma: An analysis of survival and prognostic factors. CANCER JOURNAL, 3(4), 238–245. -
Influence of fraction size, total dose, and overall time on local control of T1-T2 glottic carcinoma
LE, Q. T. X., Fu, K. K., KROLL, S., Ryu, J. K., Quivey, J. M., MEYLER, T. S., … Phillips, T. L. (1997). Influence of fraction size, total dose, and overall time on local control of T1-T2 glottic carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 39(1), 115–126. -
A medical knowledge based system for the section of beam orientations in intensity modulated radiation therapy (IMRT).
A medical knowledge based system for the section of beam orientations in intensity modulated radiation therapy (IMRT). (1998). Int J Radiat Oncol Biol Phys, 3S(45). -
Spinal cord dose discrepancy in IMRT treated patients at Stanford revealed by Monte Carlo dose verification: clinical summary.
Spinal cord dose discrepancy in IMRT treated patients at Stanford revealed by Monte Carlo dose verification: clinical summary. (1998). Int J Radiat Oncol Biol Phys, 3S(45). -
Soft-tissue sarcomas. In: Phillips TL, Leibel S, eds.
Soft-tissue sarcomas. In: Phillips TL, Leibel S, eds. (1998). Textbook of Radiation Oncology, 1st Edition. Philadelphia: WB Saunders. -
Post-operative irradiation of minor salivary gland malignancies of the head and neck.
Post-operative irradiation of minor salivary gland malignancies of the head and neck. (1999). Radiotherapy Oncology, 2(52). -
Targeting Galectin-1, a Hypoxia Induced Protein, in Non-Small Cell Lung Cancers
Banh, A., Zhang, J., Cao, H., Bouley, D., Kwok, S., Kong, C., … Le, Q. (2011). Targeting Galectin-1, a Hypoxia Induced Protein, in Non-Small Cell Lung Cancers. Presented at the European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care, STOCKHOLM,SWEDEN: ELSEVIER SCI LTD. -
Volume Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors
Trakul, N., Harris, J., Dieterich, S., Maxim, P., Le, Q., Loo, B. W., & Diehn, M. (2010). Volume Adapted Dosing in Stereotactic Ablative Radiotherapy of Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S179–S179. -
Stereotactic Ablative Radiotherapy for Previously Irradiated Lung Tumors
Trakul, N., Harris, J. P., Le, Q., Hara, W. Y., Maxim, P. G., Loo, B. W., & Diehn, M. (2011). Stereotactic Ablative Radiotherapy for Previously Irradiated Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(2), S605–S605. -
Metabolic tumor volume predicts for recurrence and death in head and neck cancer
La, T. H., Filion, E. J., Turnbull, B. B., CHU, J. N., Lee, P., Nguyen, K., … Le, Q. (2008). Metabolic tumor volume predicts for recurrence and death in head and neck cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72(1), S159–S160. -
XBP-1 regulates angiogenesis in human pancreatic adenocarcinomas
Romero-Ramirez, L., Cao, H., Regalado, M. P., Kambham, N., Siemann, D., Kim, J. J., … Koong, A. C. (2009). XBP-1 regulates angiogenesis in human pancreatic adenocarcinomas. TRANSLATIONAL ONCOLOGY, 2(1), 31–U42. -
Quantification of pre-treatment metabolic tumor growth rate in lung cancer
Eastham, D., Chapman, C. H., Rao, A. K., Balasubramanian, N., Quon, A., Vasanawala, M. S., … Loo, B. W. (2009). Quantification of pre-treatment metabolic tumor growth rate in lung cancer. JOURNAL OF THORACIC ONCOLOGY, 4(9), S733–S733. -
Does Pre-treatment Metabolic Tumor Growth Rate (MTGR) Predict Progression in Lung Cancer?
Eastham, D. V., Chapman, C. H., Rao, A. K., Narasimhan, B., Quon, A., Vasanawala, M. S., … Loo, B. W. (2009). Does Pre-treatment Metabolic Tumor Growth Rate (MTGR) Predict Progression in Lung Cancer? INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 75(3), S446–S446. -
Definitive Radiotherapy for New Primary Tumors in the Lung: The Benefit of the Doubt
Jones, J. C., Trakul, N., Hara, W., Abelson, J. A., Maxim, P., Dieterich, S., … Loo, B. W. (2010). Definitive Radiotherapy for New Primary Tumors in the Lung: The Benefit of the Doubt. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S500–S500. -
Clinical Management of Patients with Temporal Lobe Necrosis
Krakow, T. E., Hara, W., Yun, S., Soltys, S., Chang, S., Fischbein, N., … Le, Q. (2010). Clinical Management of Patients with Temporal Lobe Necrosis. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S455–S455. -
Can Temporal Lobe Necrosis be Prevented in Patients with Nasopharyngeal/Skull Base Tumors Undergoing a Stereotactic Radiosurgery Boost? A Dose Volume Analysis
Hara, W., Yun, S., Hsu, A., Soltys, S., Adler, J., Le, Q., & Loo, B. W. (2010). Can Temporal Lobe Necrosis be Prevented in Patients with Nasopharyngeal/Skull Base Tumors Undergoing a Stereotactic Radiosurgery Boost? A Dose Volume Analysis. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S431–S431. -
Radiotherapy For Adenoid Cystic Carcinomas Of The Head and Neck: Clinical Outcomes And Patterns Of Failure
Shultz, D. B., Murphy, J. D., Daly, M. E., Hara, W., Le, Q. T., & Chang, D. T. (2011). Radiotherapy For Adenoid Cystic Carcinomas Of The Head and Neck: Clinical Outcomes And Patterns Of Failure. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(2), S528–S528. -
Feasibility of Optimizing IMRT Plans Based on Measured Mucosal Dose to Adjacent Metallic Dental Fillings for Head-and-Neck Cancer Patients
Wang, L., Mok, E., Xing, L., Khong, B., Hara, W., & Le, Q. (2012). Feasibility of Optimizing IMRT Plans Based on Measured Mucosal Dose to Adjacent Metallic Dental Fillings for Head-and-Neck Cancer Patients. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(3), S462–S463. -
Volume Doubling Times and Outcomes in Stereotactic Ablative Radiotherapy of Early-stage Non-small Cell Lung Cancer
Chung, M. P., Trakul, N., Le, Q., Hara, W. Y., Dieterich, S., Maxim, P. G., … Loo, B. W. (2011). Volume Doubling Times and Outcomes in Stereotactic Ablative Radiotherapy of Early-stage Non-small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(2), S592–S592. -
Targeting Lung Tumors in Image-Guided Stereotactic Ablative Radiotherapy using Pulmonary Interstitial Lymphography
Abelson, J. A., Kothary, N., Fleischmann, D., Hofmann, L., Kielar, K. N., Maxim, P. G., … Loo, B. W. (2011). Targeting Lung Tumors in Image-Guided Stereotactic Ablative Radiotherapy using Pulmonary Interstitial Lymphography. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(2), S601–S601. -
Changes in FDG-PET/CT Parameters on Serial Pre-radiotherapy Scans Predict Disease Progression and Survival in Patients with Non-small Cell Lung Cancer
Bazan, J. G., Chung, M. P., Eastham, D. V., Wakelee, H., Hara, W. Y., Maxim, P. G., … Loo, B. W. (2011). Changes in FDG-PET/CT Parameters on Serial Pre-radiotherapy Scans Predict Disease Progression and Survival in Patients with Non-small Cell Lung Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(2), S579–S580. -
Tumor size is a critical determinant of local control in single fraction stereotactic radiotherapy of pulmonary tumors
Loo, B. W., Shen, J., Quinlan-Davidson, S., Filion, E., Dieterich, S., Maxim, P. G., … Le, Q. (2008). Tumor size is a critical determinant of local control in single fraction stereotactic radiotherapy of pulmonary tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72(1), S467–S468. -
Analysis of Migration of Implanted Markers for Image-Guided Lung Tumor Stereotactic Ablative Radiotherapy
Hong, J. C., Eclov, N. C. W., Yu, Y., Rao, A. K., Dieterich, S., Maxim, P. G., … Loo, B. W. (2011). Analysis of Migration of Implanted Markers for Image-Guided Lung Tumor Stereotactic Ablative Radiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 81(2), S580–S581. -
Mid-treatment PET predicts progression in hypofractionated accelerated radiation therapy for lung tumors
Chang, C. N., Fillion, E., Chapman, C., Rao, A., Wakelee, H., Ganjoo, K., … Loo, B. W. (2009). Mid-treatment PET predicts progression in hypofractionated accelerated radiation therapy for lung tumors. JOURNAL OF THORACIC ONCOLOGY, 4(9), S939–S939. -
Excellent early local control with tumor volume adapted dosing of stereotactic body radiation therapy for pulmonary tumors
Chang, C. N., Zhou, L. Y., MacFarlane, G., Tran, P., Rao, A., Chapman, C., … Loo, B. W. (2009). Excellent early local control with tumor volume adapted dosing of stereotactic body radiation therapy for pulmonary tumors. JOURNAL OF THORACIC ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
High Retention and Safety of Percutaneously Implanted Endovascular Embolization Coils as Fiducial Markers for Image-guided Stereotactic Ablative Radiotherapy of Pulmonary Tumors
Hong, J. C., Yu, Y., Rao, A. K., Dieterich, S., Maxim, P. G., Le, Q. T., … Loo, B. W. (2010). High Retention and Safety of Percutaneously Implanted Endovascular Embolization Coils as Fiducial Markers for Image-guided Stereotactic Ablative Radiotherapy of Pulmonary Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S518–S519. -
Radiologic Assessment of Lymph Node Involvement in HPV/p16+Oropharyngeal Cancers
Tang, C., Komakula, S., Chan, C., Murphy, J., Kong, C., Jensen, K., & Le, Q. (2012). Radiologic Assessment of Lymph Node Involvement in HPV/p16+Oropharyngeal Cancers. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(3), S473–S473. -
Identification of Pathogens in Archival Tissues Using a High-Throughput Sequencing Approach, 35EQ
SWEENEY, R. T., Brunner, A. L., Montgomery, K. D., Zhu, S. X., Kong, C., Le, Q., & West, R. B. (2012). Identification of Pathogens in Archival Tissues Using a High-Throughput Sequencing Approach, 35EQ. Presented at the 101st Annual Meeting of United-States-and-Canadian-Academy-of-Pathology (USCAP), VANCOUVER,CANADA: NATURE PUBLISHING GROUP. -
Identification of Pathogens in Archival Tissues Using a High-Throughput Sequencing Approach, 3SEQ
SWEENEY, R. T., Brunner, A. L., Montgomery, K. D., Zhu, S. X., Kong, C., Le, Q., & West, R. B. (2012). Identification of Pathogens in Archival Tissues Using a High-Throughput Sequencing Approach, 3SEQ. Presented at the 101st Annual Meeting of United-States-and-Canadian-Academy-of-Pathology (USCAP), VANCOUVER,CANADA: NATURE PUBLISHING GROUP. -
Computer-assisted selection of importance factors in inverse planning
Le, Q. T., Li, J. G., Pugachev, A., Boyer, A. L., & Xing, L. (2000). Computer-assisted selection of importance factors in inverse planning. Presented at the 13th International Conference on the Use of Computers in Radiation Therapy, HEIDELBERG,GERMANY: SPRINGER-VERLAG BERLIN. -
Towards adaptive radiation therapy: Image-based tumor shrinkage modeling in head and neck cancer
Chao, M., Xie, Y., Le, Q., & Xing, L. (2009). Towards adaptive radiation therapy: Image-based tumor shrinkage modeling in head and neck cancer. JOURNAL OF CLINICAL ONCOLOGY, 27(15). -
Retrospective IMRT dose reconstruction based on cone-beam computed tomography (CBCT) and the MLC positional log-file recorded during treatment
Lee, K., Le, Q., & Xing, L. (2007). Retrospective IMRT dose reconstruction based on cone-beam computed tomography (CBCT) and the MLC positional log-file recorded during treatment. MEDICAL PHYSICS, 34(6), 2600–2600. -
Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire
Epstein, J. B., Beaumont, J. L., Gwede, C. K., Murphy, B., Garden, A. S., Meredith, R., … Cella, D. (2007). Longitudinal evaluation of the oral mucositis weekly questionnaire-head and neck cancer, a patient-reported outcomes questionnaire. CANCER, 109(9), 1914–1922. -
Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial
Rischin, D., Young, R., Fisher, R., Fox, S., Le, Q., Peters, L., … McArthur, G. (2009). Prognostic significance of HPV and p16 status in patients with oropharyngeal cancer treated on a large international phase III trial. JOURNAL OF CLINICAL ONCOLOGY, 27(15). -
A differentiation based immunohistochemical classifier that is prognostic for head and neck tumor patients
Ross, D. T., Ring, B. Z., Seitz, R. S., Beck, R. A., DeFoe, S., Robert, F., … Le, Q. T. (2007). A differentiation based immunohistochemical classifier that is prognostic for head and neck tumor patients. Presented at the 96th Annual Meeting of the United-States-and-Canadian-Academy-of-Pathology, SAN DIEGO,CA: NATURE PUBLISHING GROUP. -
Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head and Neck Cancer Outcomes
Chu, K. P. M., Murphy, J., La, T. H., Loo, B. W., Krakow, T. E., Hsu, A., … Le, Q. (2010). Prognostic Value of Metabolic Tumor Volume and Velocity in Predicting Head and Neck Cancer Outcomes. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 78(3), S460–S460. -
A Novel Aldehyde Dehydrogenase-3 Activator (Alda-89) Protects Submandibular Gland Function from Irradiation without Accelerating Tumor Growth.
Xiao, N., Cao, H., Chen, C.-H., Kong, C. S., Ali, R., Chan, C., … Le, Q.-T. (2013). A Novel Aldehyde Dehydrogenase-3 Activator (Alda-89) Protects Submandibular Gland Function from Irradiation without Accelerating Tumor Growth. Clinical Cancer Research , 19(16), 4455–64. -
Feasibility of Pulmonary Interstitial Lymphography-guided Targeting in Stereotactic Ablative Radiation Therapy of Lung Tumors
Abelson, J. A., Kothary, N., Fleischmann, D., Hofmann, L., Kielar, K., Maxim, P., … Loo, B. W. (2012). Feasibility of Pulmonary Interstitial Lymphography-guided Targeting in Stereotactic Ablative Radiation Therapy of Lung Tumors. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 84(3), S173–S173. -
Relationship between human papillomavirus (HPV) status, epidermal growth factor receptor (EGFR) and Phospho-EGFR (pEGFR) expression in head and neck squamous cell carcinoma (HNSCC)
Filion, E. J., Kong, C. S., Narasimhan, B., Cao, H., Erickson, J. P., Andersson, A., … Le, Q. (2008). Relationship between human papillomavirus (HPV) status, epidermal growth factor receptor (EGFR) and Phospho-EGFR (pEGFR) expression in head and neck squamous cell carcinoma (HNSCC). INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 72(1), S23–S23. -
The Unique Microenvironments of Spontaneous Tumors Differentially Sensitize Them to Radiation
Spiotto, M. T., Bahn, A., Cao, H., Le, Q., & Koong, A. C. (2009). The Unique Microenvironments of Spontaneous Tumors Differentially Sensitize Them to Radiation. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 75(3), S171–S171. -
Detection of circulating hypoxia-regulated miR-210 in pancreatic adenocarcinoma patients
Ho, A. S., Huang, X., Cao, H., Koong, A. C., & Le, Q. T. (2009). Detection of circulating hypoxia-regulated miR-210 in pancreatic adenocarcinoma patients. JOURNAL OF CLINICAL ONCOLOGY, 27(15). -
Radio logic assessment of retropharyngeal node involvement in oropharyngeal carcinomas stratified by HPV status
Tang, C., Komakula, S., Chan, C., Murphy, J. D., Jiang, W., Kong, C., … Quynh-Thu Le, Q. T. (2013). Radio logic assessment of retropharyngeal node involvement in oropharyngeal carcinomas stratified by HPV status. RADIOTHERAPY AND ONCOLOGY, 109(2), 293–96. -
Radiologic assessment of retropharyngeal node involvement in oropharyngeal carcinomas stratified by HPV status.
Tang, C., Komakula, S., Chan, C., Murphy, J. D., Jiang, W., Kong, C., … Le, Q.-T. (2013). Radiologic assessment of retropharyngeal node involvement in oropharyngeal carcinomas stratified by HPV status. Radiotherapy and Oncology , 109(2), 293–96. -
Thymic Malignancies
Ettinger, D. S., Akerley, W., Bepler, G., Blum, M. G., Chang, A., Cheney, R. T., … Yang, S. C. (2010). Thymic Malignancies. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 8(11), 1302–15. -
Discovery of recurrent structural variants in nasopharyngeal carcinoma.
Valouev, A., Weng, Z., Sweeney, R. T., Varma, S., Le, Q.-T., Kong, C., … West, R. B. (2014). Discovery of recurrent structural variants in nasopharyngeal carcinoma. Genome Research, 24(2), 300–309. -
A Population-Based Comparative Effectiveness Study of Radiation Therapy Techniques in Stage III Non-Small Cell Lung Cancer.
Harris, J. P., Murphy, J. D., Hanlon, A. L., Le, Q.-T., Loo, B. W., & Diehn, M. (2014). A Population-Based Comparative Effectiveness Study of Radiation Therapy Techniques in Stage III Non-Small Cell Lung Cancer. International Journal of Radiation Oncology, Biology, Physics, 88(4), 872–84. -
Clinical impact of dose overestimation by effective path length calculation in stereotactic ablative radiation therapy of lung tumors.
Liu, M. B., Eclov, N. C. W., Trakul, N., Murphy, J., Diehn, M., Le, Q.-T., … Loo, B. W. (2013). Clinical impact of dose overestimation by effective path length calculation in stereotactic ablative radiation therapy of lung tumors. Practical Radiation Oncology, 3(4), 294–300. -
Evaluation of a metal artifact reduction technique in tonsillar cancer delineation.
Abelson, J. A., Murphy, J. D., Wiegner, E. A., Abelson, D., Sandman, D. N., Boas, F. E., … Le, Q.-T. (2012). Evaluation of a metal artifact reduction technique in tonsillar cancer delineation. Practical Radiation Oncology, 2(1), 27–34. -
Risk Factors for Clinician-Reported Symptom Clusters in Patients With Advanced Head and Neck Cancer in a Phase 3 Randomized Clinical Trial: RTOG 0129
Xiao, C., Hanlon, A., Zhang, Q., Movsas, B., Ang, K., Rosenthal, D. I., … Bruner, D. W. (2014). Risk Factors for Clinician-Reported Symptom Clusters in Patients With Advanced Head and Neck Cancer in a Phase 3 Randomized Clinical Trial: RTOG 0129. CANCER, 120(6), 848–54. -
Imaging features associated with disease progression after stereotactic ablative radiotherapy for stage I non-small-cell lung cancer.
Shultz, D. B., Trakul, N., Abelson, J. A., Murphy, J. D., Maxim, P. G., Le, Q.-T., … Diehn, M. (2014). Imaging features associated with disease progression after stereotactic ablative radiotherapy for stage I non-small-cell lung cancer. Clinical Lung Cancer, 15(4), 294–301 e3. -
Racial Disparity in Consultation, Treatment, and the Impact on Survival in Metastatic Colorectal Cancer
Simpson, D. R., Martinez, M. E., Gupta, S., Hattangadi-Gluth, J., Mell, L. K., Heestand, G., … Murphy, J. D. (2013). Racial Disparity in Consultation, Treatment, and the Impact on Survival in Metastatic Colorectal Cancer. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 105(23), 1814–20. -
Image-guided extracranial radiosurgery
Sattah, M., Guerrero, T., Chang, S., Martin, D., Le, Q. T., Gibbs, I., & Adler, J. (2001). Image-guided extracranial radiosurgery. Presented at the 7th International Meeting on Progress in Radio-Oncology (ICRO/OGRO 7), SALZBURG,AUSTRIA: MEDIMOND S R L. -
Neurotrophic factor GDNF promotes survival of salivary stem cells.
Xiao, N., Lin, Y., Cao, H., Sirjani, D., Giaccia, A. J., Koong, A. C., … Le, Q.-T. (2014). Neurotrophic factor GDNF promotes survival of salivary stem cells. Journal of Clinical Investigation, 124(8), 3364–77. -
CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma.
Murillo-Sauca, O., Chung, M. K., Shin, J. H., Karamboulas, C., Kwok, S., Jung, Y. H., … Sunwoo, J. B. (2014). CD271 is a functional and targetable marker of tumor-initiating cells in head and neck squamous cell carcinoma. Oncotarget, 5(16), 6854–66. -
Galectin-1 links tumor hypoxia and radiotherapy.
Kuo, P., & Le, Q.-T. (2014). Galectin-1 links tumor hypoxia and radiotherapy. Glycobiology, 24(10), 921–25. -
A unifying probabilistic Bayesian approach to derive electron density from MRI for radiation therapy treatment planning.
Gudur, M. S. R., Hara, W., Le, Q.-T., Wang, L., Xing, L., & Li, R. (2014). A unifying probabilistic Bayesian approach to derive electron density from MRI for radiation therapy treatment planning. Physics in Medicine and Biology, 59(21), 6595–6606. -
Commutability of the Epstein-Barr Virus WHO International Standard across Two Quantitative PCR Methods
Abeynayake, J., Johnson, R., Libiran, P., Sahoo, M. K., Cao, H., Bowen, R., … Pinsky, B. A. (2014). Commutability of the Epstein-Barr Virus WHO International Standard across Two Quantitative PCR Methods. JOURNAL OF CLINICAL MICROBIOLOGY, 52(10), 3802–4. -
Age Disparity in Palliative Radiation Therapy Among Patients With Advanced Cancer
Wong, J., Xu, B., Yeung, H. N., Roeland, E. J., Martinez, M. E., Quynh-Thu Le, Q. T., … Murphy, J. D. (2014). Age Disparity in Palliative Radiation Therapy Among Patients With Advanced Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 90(1), 224–30. -
Galectin-1 mediates radiation-related lymphopenia and attenuates NSCLC radiation response.
Kuo, P., Bratman, S. V., Shultz, D. B., von Eyben, R., Chan, C., Wang, Z., … Le, Q.-T. (2014). Galectin-1 mediates radiation-related lymphopenia and attenuates NSCLC radiation response. Clinical Cancer Research , 20(21), 5558–69. -
A unifying probabilistic Bayesian approach to derive electron density from MRI for radiation therapy treatment planning
Gudur, M. S. R., Hara, W., Le, Q.-T., Wang, L., Xing, L., & Li, R. (2014). A unifying probabilistic Bayesian approach to derive electron density from MRI for radiation therapy treatment planning. PHYSICS IN MEDICINE AND BIOLOGY, 59(21), 6595–6606. -
Institutional clinical trial accrual volume and survival of patients with head and neck cancer.
Wuthrick, E. J., Zhang, Q., Machtay, M., Rosenthal, D. I., Nguyen-Tan, P. F., Fortin, A., … Gillison, M. L. (2015). Institutional clinical trial accrual volume and survival of patients with head and neck cancer. Journal of Clinical Oncology , 33(2), 156–64. -
Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma.
Fakhry, C., Zhang, Q., Nguyen-Tan, P. F., Rosenthal, D., El-Naggar, A., Garden, A. S., … Gillison, M. (2014). Human papillomavirus and overall survival after progression of oropharyngeal squamous cell carcinoma. Journal of Clinical Oncology , 32(30), 3365–73. -
p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma.
Chung, C. H., Zhang, Q., Kong, C. S., Harris, J., Fertig, E. J., Harari, P. M., … Le, Q.-T. (2014). p16 protein expression and human papillomavirus status as prognostic biomarkers of nonoropharyngeal head and neck squamous cell carcinoma. Journal of Clinical Oncology , 32(35), 3930–38. -
Concurrent cetuximab versus platinum-based chemoradiation for the definitive treatment of locoregionally advanced head and neck cancer.
Tang, C., Chan, C., Jiang, W., Murphy, J. D., von Eyben, R., Colevas, A. D., … Le, Q.-T. (2015). Concurrent cetuximab versus platinum-based chemoradiation for the definitive treatment of locoregionally advanced head and neck cancer. Head & Neck, 37(3), 386–92. -
Prognostic model for distant metastasis in locally advanced nasopharyngeal carcinoma after concurrent chemoradiotherapy
Chen, C., Chen, S., Le, Q.-T., Chen, J., Chen, Z., Li, D., … Li, D. (2015). Prognostic model for distant metastasis in locally advanced nasopharyngeal carcinoma after concurrent chemoradiotherapy. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK, 37(2), 209–14. -
Survival benefit for adjuvant radiation therapy in minor salivary gland cancers.
Zeidan, Y. H., Pekelis, L., An, Y., Holsinger, F. C., Kong, C. S., Chang, D. T., & Le, Q.-T. (2015). Survival benefit for adjuvant radiation therapy in minor salivary gland cancers. Oral Oncology, 51(5), 438–45. -
Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose
Chung, C. H., Mirakhur, B., Chan, E., Le, Q.-T., Berlin, J., Morse, M., … Platts-Mills, T. A. E. (2008). Cetuximab-induced anaphylaxis and IgE specific for galactose-alpha-1,3-galactose. NEW ENGLAND JOURNAL OF MEDICINE, 358(11), 1109–17. -
New developments in radiation therapy for head and neck cancer: Intensity-modulated radiation therapy and hypoxia targeting
Lee, N. Y., & Le, Q.-T. (2008). New developments in radiation therapy for head and neck cancer: Intensity-modulated radiation therapy and hypoxia targeting. SEMINARS IN ONCOLOGY, 35(3), 236–50. -
Patterns of care in palliative radiotherapy: a population-based study.
Murphy, J. D., Nelson, L. M., Chang, D. T., Mell, L. K., & Le, Q.-T. (2013). Patterns of care in palliative radiotherapy: a population-based study. Journal of Oncology Practice / American Society of Clinical Oncology, 9(5), e220–7. -
Radiation Resistance in Cancer Therapy: meeting summary and research opportunities. Report of an NCI Workshop held September 1-3, 2010.
Glazer, P. M., Grandis, J., Powell, S. N., Brown, J. M., Helleday, T., Bristow, R., … Bernhard, E. J. (2011). Radiation Resistance in Cancer Therapy: meeting summary and research opportunities. Report of an NCI Workshop held September 1-3, 2010. Radiation Research, 176(3), e0016–21. -
Molecular profiling to optimize treatment in non-small cell lung cancer: a review of potential molecular targets for radiation therapy by the translational research program of the radiation therapy oncology group.
Ausborn, N. L., Le, Q. T., Bradley, J. D., Choy, H., Dicker, A. P., Saha, D., … Lu, B. (2012). Molecular profiling to optimize treatment in non-small cell lung cancer: a review of potential molecular targets for radiation therapy by the translational research program of the radiation therapy oncology group. International Journal of Radiation Oncology, Biology, Physics, 83(4), e453–64. -
Gastrointestinal Toxicities With Combined Antiangiogenic and Stereotactic Body Radiation Therapy.
Pollom, E. L., Deng, L., Pai, R. K., Brown, J. M., Giaccia, A., Loo, B. W., … Chang, D. T. (2015). Gastrointestinal Toxicities With Combined Antiangiogenic and Stereotactic Body Radiation Therapy. International Journal of Radiation Oncology, Biology, Physics, 92(3), 568–76. -
Colorectal Histology Is Associated With an Increased Risk of Local Failure in Lung Metastases Treated With Stereotactic Ablative Radiation Therapy
Binkley, M. S., Trakul, N., Jacobs, L. R., von Eyben, R., Quynh-Thu Le, Q. T., Maxim, P. G., … Diehn, M. (2015). Colorectal Histology Is Associated With an Increased Risk of Local Failure in Lung Metastases Treated With Stereotactic Ablative Radiation Therapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 92(5), 1044–52. -
TU-AB-BRA-10: Prognostic Value of Intra-Radiation Treatment FDG-PET and CT Imaging Features in Locally Advanced Head and Neck Cancer.
Song, J., Cui, Y., Pollom, E., Durkee, B., Aggarwal, S., Bui, T., … Li, R. (2015). TU-AB-BRA-10: Prognostic Value of Intra-Radiation Treatment FDG-PET and CT Imaging Features in Locally Advanced Head and Neck Cancer. Medical Physics, 42(6), 3588-? -
Aspiration pneumonia after concurrent chemoradiotherapy for head and neck cancer.
Xu, B., Boero, I. J., Hwang, L., Le, Q.-T., Moiseenko, V., Sanghvi, P. R., … Murphy, J. D. (2015). Aspiration pneumonia after concurrent chemoradiotherapy for head and neck cancer. Cancer, 121(8), 1303–1311. -
Results of a phase 2 study examining the effects of omitting elective neck irradiation to nodal levels IV and Vb in patients with N(0-1) nasopharyngeal carcinoma.
Chen, J.-zhou, Le, Q.-T., Han, F., Lu, L.-X., Huang, S.-M., Lin, C.-guang, … Zhao, C. (2013). Results of a phase 2 study examining the effects of omitting elective neck irradiation to nodal levels IV and Vb in patients with N(0-1) nasopharyngeal carcinoma. International Journal of Radiation Oncology, Biology, Physics, 85(4), 929–934. -
Reply to B. O'Sullivan et Al.
Fakhry, C., Zhang, Q., Nguyen-Tan, P. F., Rosenthal, D., El-Naggar, A. K., Garden, A. S., … Gillison, M. (2015). Reply to B. O'Sullivan et Al. Journal of Clinical Oncology , 33(15), 1708–9. -
New translational possibilities for microenvironmental modulation of radiosensitivity.
Glazer, P. M., Le, Q.-T., Bristow, R., Helleday, T., Pelroy, R., & Bernhard, E. J. (2011). New translational possibilities for microenvironmental modulation of radiosensitivity. Radiation Research, 176(3), 412–414. -
Emerging Treatment Paradigms in Radiation Oncology.
Le, Q.-T., Shirato, H., Giaccia, A. J., & Koong, A. C. (2015). Emerging Treatment Paradigms in Radiation Oncology. Clinical Cancer Research , 21(15), 3393–3401. -
Commutability of the Epstein-Barr virus WHO international standard across two quantitative PCR methods.
Abeynayake, J., Johnson, R., Libiran, P., Sahoo, M. K., Cao, H., Bowen, R., … Pinsky, B. A. (2014). Commutability of the Epstein-Barr virus WHO international standard across two quantitative PCR methods. Journal of Clinical Microbiology, 52(10), 3802–4. -
Metabolic tumor volume as a prognostic imaging-based biomarker for head-and-neck cancer: pilot results from Radiation Therapy Oncology Group protocol 0522.
Schwartz, D. L., Harris, J., Yao, M., Rosenthal, D. I., Opanowski, A., Levering, A., … Le, Q.-T. (2015). Metabolic tumor volume as a prognostic imaging-based biomarker for head-and-neck cancer: pilot results from Radiation Therapy Oncology Group protocol 0522. International Journal of Radiation Oncology, Biology, Physics, 91(4), 721–29. -
Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity.
Nguyen-Tan, P. F., Zhang, Q., Ang, K. K., Weber, R. S., Rosenthal, D. I., Soulieres, D., … Le, Q.-T. (2014). Randomized phase III trial to test accelerated versus standard fractionation in combination with concurrent cisplatin for head and neck carcinomas in the Radiation Therapy Oncology Group 0129 trial: long-term report of efficacy and toxicity. Journal of Clinical Oncology , 32(34), 3858–66. -
ß-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging.
King, M. T., Carpenter, C. M., Sun, C., Ma, X., Le, Q.-T., Sunwoo, J. B., … Xing, L. (2015). ß-Radioluminescence Imaging: A Comparative Evaluation with Cerenkov Luminescence Imaging. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 56(9), 1458–64. -
Palliative Radiation Before Hospice: The Long and the Short of It
Yeung, H. N., Mitchell, W. M., Roeland, E. J., Xu, B., Mell, L. K., Quynh-Thu Le, Q. T., & Murphy, J. D. (2014). Palliative Radiation Before Hospice: The Long and the Short of It. JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 48(6), 1070–79. -
A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers.
Pollom, E. L., Wang, E., Bui, T. T., Ognibene, G., von Eyben, R., Divi, V., … Hara, W. Y. (2015). A prospective study of electronic quality of life assessment using tablet devices during and after treatment of head and neck cancers. Oral Oncology, 51(12), 1132–37. -
Quantitative and qualitative analysis of [(18)F]FDG and [(18)F]FAZA positron emission tomography of head and neck cancers and associations with HPV status and treatment outcome.
Graves, E. E., Hicks, R. J., Binns, D., Bressel, M., Le, Q.-T., Peters, L., … Rischin, D. (2016). Quantitative and qualitative analysis of [(18)F]FDG and [(18)F]FAZA positron emission tomography of head and neck cancers and associations with HPV status and treatment outcome. European Journal of Nuclear Medicine and Molecular Imaging, 43(4), 617–25. -
Prognostic value of midtreatment FDG-PET in oropharyngeal cancer.
Pollom, E. L., Song, J., Durkee, B. Y., Aggarwal, S., Bui, T., von Eyben, R., … Hara, W. Y. (2016). Prognostic value of midtreatment FDG-PET in oropharyngeal cancer. Head & Neck, 38(10), 1472–78. -
Proposal for the 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy.
Pan, J. J., Ng, W. T., Zong, J. F., Chan, L. L. K., O'Sullivan, B., Lin, S. J., … Lee, A. W. M. (2016). Proposal for the 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy. Cancer, 122(4), 546–58. -
Botulinum Toxin Confers Radioprotection in Murine Salivary Glands
Zeidan, Y. H., Xiao, N., Cao, H., Kong, C., Le, Q.-T., & Sirjani, D. (2016). Botulinum Toxin Confers Radioprotection in Murine Salivary Glands. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 94(5), 1190–97. -
Importance of Radiation Oncologist Experience Among Patients With Head-and-Neck Cancer Treated With Intensity-Modulated Radiation Therapy.
Boero, I. J., Paravati, A. J., Xu, B., Cohen, E. E. W., Mell, L. K., Le, Q.-T., & Murphy, J. D. (2016). Importance of Radiation Oncologist Experience Among Patients With Head-and-Neck Cancer Treated With Intensity-Modulated Radiation Therapy. Journal of Clinical Oncology , 34(7), 684–90. -
Long-term results of radiation therapy oncology group 9903: a randomized phase 3 trial to assess the effect of erythropoietin on local-regional control in anemic patients treated with radiation therapy for squamous cell carcinoma of the head and neck.
Shenouda, G., Zhang, Q., Ang, K. K., Machtay, M., Parliament, M. B., Hershock, D., … Le, Q.-T. (2015). Long-term results of radiation therapy oncology group 9903: a randomized phase 3 trial to assess the effect of erythropoietin on local-regional control in anemic patients treated with radiation therapy for squamous cell carcinoma of the head and neck. International Journal of Radiation Oncology, Biology, Physics, 91(5), 907–15. -
Age disparity in palliative radiation therapy among patients with advanced cancer.
Wong, J., Xu, B., Yeung, H. N., Roeland, E. J., Martinez, M. E., Le, Q.-T., … Murphy, J. D. (2014). Age disparity in palliative radiation therapy among patients with advanced cancer. International Journal of Radiation Oncology, Biology, Physics, 90(1), 224–30. -
Botulinum Toxin Confers Radioprotection in Murine Salivary Glands.
Zeidan, Y. H., Xiao, N., Cao, H., Kong, C., Le, Q.-T., & Sirjani, D. (2016). Botulinum Toxin Confers Radioprotection in Murine Salivary Glands. International Journal of Radiation Oncology, Biology, Physics, 94(5), 1190–97. -
Neurotrophic Factors and Their Potential Applications in Tissue Regeneration.
Xiao, N., & Le, Q.-T. (2016). Neurotrophic Factors and Their Potential Applications in Tissue Regeneration. Archivum Immunologiae Et Therapiae Experimentalis, 64(2), 89–99. -
Pre-treatment non-target lung FDG-PET uptake predicts symptomatic radiation pneumonitis following Stereotactic Ablative Radiotherapy (SABR).
Chaudhuri, A. A., Binkley, M. S., Rigdon, J., Carter, J. N., Aggarwal, S., Dudley, S. A., … Guo, H. H. (2016). Pre-treatment non-target lung FDG-PET uptake predicts symptomatic radiation pneumonitis following Stereotactic Ablative Radiotherapy (SABR). Radiotherapy and Oncology , 119(3), 454–60. -
Acridine Derivatives as Inhibitors of the IRE1a-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma.
Jiang, D., Tam, A. B., Alagappan, M., Hay, M. P., Gupta, A., Kozak, M. M., … Koong, A. C. (2016). Acridine Derivatives as Inhibitors of the IRE1a-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma. Molecular Cancer Therapeutics, 15(9), 2055–65. -
Design and rationale of a prospective multi-institutional registry for patients with sinosodal malignancy
Beswick, D. M., Holsinger, F. C., Kaplan, M. J., Fischbein, N. J., Hara, W. Y., Colevas, A. D., … Hwang, P. H. (2016). Design and rationale of a prospective multi-institutional registry for patients with sinosodal malignancy. The Laryngoscope, ([Epub ahead of print]). -
Establishing quality indicators for neck dissection: Correlating the number of lymph nodes with oncologic outcomes (NRG Oncology RTOG 9501 and RTOG 0234).
Divi, V., Harris, J., Harari, P. M., Cooper, J. S., McHugh, J., Bell, D., … Holsinger, F. C. (2016). Establishing quality indicators for neck dissection: Correlating the number of lymph nodes with oncologic outcomes (NRG Oncology RTOG 9501 and RTOG 0234). Cancer. -
Design and rationale of a prospective, multi-institutional registry for patients with sinonasal malignancy.
Beswick, D. M., Holsinger, F. C., Kaplan, M. J., Fischbein, N. J., Hara, W., Colevas, A. D., … Hwang, P. H. (2016). Design and rationale of a prospective, multi-institutional registry for patients with sinonasal malignancy. Laryngoscope, 126(9), 1977–80. -
Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours.
Golias, T., Papandreou, I., Sun, R., Kumar, B., Brown, N. V., Swanson, B. J., … Denko, N. C. (2016). Hypoxic repression of pyruvate dehydrogenase activity is necessary for metabolic reprogramming and growth of model tumours. Scientific Reports, 6, 31146-? -
Correlation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience.
Bar-Ad, V., Zhang, Q. E., Harari, P. M., Axelrod, R., Rosenthal, D. I., Trotti, A., … Le, Q.-T. (2016). Correlation Between the Severity of Cetuximab-Induced Skin Rash and Clinical Outcome for Head and Neck Cancer Patients: The RTOG Experience. International Journal of Radiation Oncology, Biology, Physics, 95(5), 1346–54. -
Identification of Doxorubicin as an Inhibitor of the IRE1a-XBP1 Axis of the Unfolded Protein Response.
Jiang, D., Lynch, C., Medeiros, B. C., Liedtke, M., Bam, R., Tam, A. B., … Koong, A. C. (2016). Identification of Doxorubicin as an Inhibitor of the IRE1a-XBP1 Axis of the Unfolded Protein Response. Scientific Reports, 6, 33353-? -
Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis.
Bhat, R., Belardi, B., Mori, H., Kuo, P., Tam, A., Hines, W. C., … Bissell, M. J. (2016). Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis. Proceedings of the National Academy of Sciences of the United States of America, 113(33), E4820–7. -
Prognostic Value of p16 Status on the Development of a Complete Response in Involved Oropharynx Cancer Neck Nodes After Cisplatin-Based Chemoradiation: A Secondary Analysis of NRG Oncology RTOG 0129.
Galloway, T. J., Zhang, Q. E., Nguyen-Tan, P. F., Rosenthal, D. I., Soulieres, D., Fortin, A., … Le, Q.-T. (2016). Prognostic Value of p16 Status on the Development of a Complete Response in Involved Oropharynx Cancer Neck Nodes After Cisplatin-Based Chemoradiation: A Secondary Analysis of NRG Oncology RTOG 0129. International Journal of Radiation Oncology, Biology, Physics, 96(2), 362–71. -
Radiographic assessment of the sinuses in patients treated for nasopharyngeal carcinoma
Raviv, J., Downing, L., Le, Q.-T., & Hwang, P. (2008). Radiographic assessment of the sinuses in patients treated for nasopharyngeal carcinoma. AMERICAN JOURNAL OF RHINOLOGY, 22(1), 64–67. -
The Application of FDG-PET as Prognostic Indicators in Head and Neck Squamous Cell Carcinoma.
Siddiqui, F., Faulhaber, P. F., Yao, M., & Le, Q.-T. (2012). The Application of FDG-PET as Prognostic Indicators in Head and Neck Squamous Cell Carcinoma. PET Clinics, 7(4), 381–94. -
Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129.
Xiao, C., Zhang, Q., Nguyen-Tân, P. F., List, M., Weber, R. S., Ang, K. K., … Bruner, D. (2016). Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Standard Radiation Versus Accelerated Radiation Plus Cisplatin for Locally Advanced Head and Neck Carcinoma: NRG Oncology RTOG 0129. International Journal of Radiation Oncology, Biology, Physics. -
Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522.
Truong, M. T., Zhang, Q., Rosenthal, D. I., List, M., Axelrod, R., Sherman, E., … Bruner, D. (2016). Quality of Life and Performance Status From a Substudy Conducted Within a Prospective Phase 3 Randomized Trial of Concurrent Accelerated Radiation Plus Cisplatin With or Without Cetuximab for Locally Advanced Head and Neck Carcinoma: NRG Oncology Radiation Therapy Oncology Group 0522. International Journal of Radiation Oncology, Biology, Physics. -
Flexible radioluminescence imaging for FDG-guided surgery
King, M. T., Jenkins, C. H., Sun, C., Carpenter, C. M., Ma, X., Cheng, K., … Xing, L. (2016). Flexible radioluminescence imaging for FDG-guided surgery. MEDICAL PHYSICS, 43(10). -
Prognostic nomogram for refining the prognostication of the proposed 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy.
Pan, J. J., Ng, W. T., Zong, J. F., Lee, S. W. M., Choi, H. C. W., Chan, L. L. K., … Lee, A. W. M. (2016). Prognostic nomogram for refining the prognostication of the proposed 8th edition of the AJCC/UICC staging system for nasopharyngeal cancer in the era of intensity-modulated radiotherapy. Cancer, 122(21), 3307–15. -
Galectin-1 links tumor hypoxia and radiotherapy
Kuo, P., & Quynh-Thu Le, Q. T. (2014). Galectin-1 links tumor hypoxia and radiotherapy. GLYCOBIOLOGY, 24(10), 921–925. -
Robust Estimation of Electron Density From Anatomic Magnetic Resonance Imaging of the Brain Using a Unifying Multi-Atlas Approach.
Ren, S., Hara, W., Wang, L., Buyyounouski, M. K., Le, Q.-T., Xing, L., & Li, R. (2017). Robust Estimation of Electron Density From Anatomic Magnetic Resonance Imaging of the Brain Using a Unifying Multi-Atlas Approach. International Journal of Radiation Oncology, Biology, Physics, 97(4), 849–57. -
Radiation Resistance in Cancer Therapy: Meeting Summary and Research Opportunities: Report of an NCI Workshop held September 1-3, 2010.
Glazer, P. M., Grandis, J., Powell, S. N., Brown, J. M., Helleday, T., Bristow, R., … Bernhard, E. J. (2011). Radiation Resistance in Cancer Therapy: Meeting Summary and Research Opportunities: Report of an NCI Workshop held September 1-3, 2010. Radiation Research, -? -
Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting.
Bauman, J. E., Cohen, E., Ferris, R. L., Adelstein, D. J., Brizel, D. M., Ridge, J. A., … Malik, S. (2016). Immunotherapy of head and neck cancer: Emerging clinical trials from a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting. Cancer. -
The role of postoperative chemoradiation for oropharynx carcinoma: A critical appraisal revisited.
Cooper, J. S., Fortpied, C., Gregoire, V., Le, Q.-T., Pajak, T. F., Zhang, Q. E., & Bernier, J. (2017). The role of postoperative chemoradiation for oropharynx carcinoma: A critical appraisal revisited. Cancer, 123(1), 12–16. -
Immunotherapy of Head and Neck Cancer: Emerging Clinical Trials From a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting
Bauman, J. E., Cohen, E., Ferris, R. L., Adelstein, D. J., Brizel, D. M., Ridge, J. A., … Malik, S. (2017). Immunotherapy of Head and Neck Cancer: Emerging Clinical Trials From a National Cancer Institute Head and Neck Cancer Steering Committee Planning Meeting. CANCER, 123(7), 1259–71. -
The impact of developing a speech and swallow rehab program: Improving patient satisfaction and multidisciplinary care.
Starmer, H. M., Ayoub, N., Byward, C., Kizner, J., Le, Q., Hara, W., & Holsinger, F. C. (2017). The impact of developing a speech and swallow rehab program: Improving patient satisfaction and multidisciplinary care. Laryngoscope. -
Very high-energy electron (VHEE) beams in radiation therapy; Treatment plan comparison between VHEE, VMAT, and PPBS.
Schüler, E., Eriksson, K., Hynning, E., Hancock, S. L., Hiniker, S. M., Bazalova-Carter, M., … Maxim, P. G. (2017). Very high-energy electron (VHEE) beams in radiation therapy; Treatment plan comparison between VHEE, VMAT, and PPBS. Medical Physics. -
A Human Genome-wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1a-XBP1 Activation.
Yang, Z., Zhang, J., Jiang, D., Khatri, P., Solow-Cordero, D. E., Toesca, D. A., … Koong, A. C. (2018). A Human Genome-wide RNAi Screen Reveals Diverse Modulators that Mediate IRE1a-XBP1 Activation. Molecular Cancer Research : MCR. -
Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines
Gregoire, V., Evans, M., Quynh-Thu Le, Bourhis, J., Budach, V., Chen, A., … Grau, C. (2018). Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines. RADIOTHERAPY AND ONCOLOGY. ELSEVIER IRELAND LTD. -
Meeting Viewpoint
Ahmed, M. M., Coleman, C. N., Mendonca, M., Bentzen, S., Vikram, B., Seltzer, S. M., … Mitchell, J. (2018). Meeting Viewpoint. CANCER RESEARCH, 78(9), 2166–70. -
Development and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer
Fakhry, C., Zhang, Q., Nguyen-Tan, P. F., Rosenthal, D. I., Weber, R. S., Lambert, L., … Gillison, M. L. (2017). Development and Validation of Nomograms Predictive of Overall and Progression-Free Survival in Patients With Oropharyngeal Cancer. JOURNAL OF CLINICAL ONCOLOGY, 35(36), 4057-+. -
International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma
Lee, A. W., Ng, W. T., Pan, J. J., Poh, S. S., Ahn, Y. C., AlHussain, H., … Wee, J. T. (2018). International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma. RADIOTHERAPY AND ONCOLOGY. ELSEVIER IRELAND LTD. -
Mid-radiotherapy PET/CT for prognostication and detection of early progression in patients with stage III non-small cell lung cancer
Gensheimer, M. F., Hong, J. C., Chang-Halpenny, C., Zhu, H., Eclov, N. C. W., To, J., … Loo, B. W. (2017). Mid-radiotherapy PET/CT for prognostication and detection of early progression in patients with stage III non-small cell lung cancer. RADIOTHERAPY AND ONCOLOGY, 125(2), 338–43. -
Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.
Saiki, J. P., Cao, H., Van Wassenhove, L. D., Viswanathan, V., Bloomstein, J., Nambiar, D. K., … Mochly-Rosen, D. (2018). Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes. Proceedings of the National Academy of Sciences of the United States of America. -
Future cancer research priorities in the USA: a Lancet Oncology Commission
Jaffee, E. M., Dang, C. V., Agus, D. B., Alexander, B. M., Anderson, K. C., Ashworth, A., … Yung, A. (2017). Future cancer research priorities in the USA: a Lancet Oncology Commission. LANCET ONCOLOGY, 18(11), E653–E706. -
Clinical Utility of Epstein-Barr Virus DNA Testing in the Treatment of Nasopharyngeal Carcinoma Patients Reply
Le, Q.-T., Yom, S. S., Ng, R. H. W., Bratman, S. V., Welch, J. J., Chan, K. C. A., & Kim, K. Y. (2017). Clinical Utility of Epstein-Barr Virus DNA Testing in the Treatment of Nasopharyngeal Carcinoma Patients Reply. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 99(5), 1307. -
Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology
Bristow, R. G., Alexander, B., Baumann, M., Bratman, S. V., Brown, J. M., Camphausen, K., … Harari, P. M. (2018). Combining precision radiotherapy with molecular targeting and immunomodulatory agents: a guideline by the American Society for Radiation Oncology. LANCET ONCOLOGY, 19(5), E240–E251. -
Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update
Forastiere, A. A., Ismaila, N., Lewin, J. S., Nathan, C. A., Adelstein, D. J., Eisbruch, A., … Wolf, G. T. (2018). Use of Larynx-Preservation Strategies in the Treatment of Laryngeal Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update. JOURNAL OF CLINICAL ONCOLOGY, 36(11), 1143-+. -
Midtreatment metabolic imaging as a biomarker of treatment response
Le, Q.-T. (2017). Midtreatment metabolic imaging as a biomarker of treatment response. CLINICAL CANCER RESEARCH, 23(23). -
Selection of external beam radiotherapy approaches for precise and accurate cancer treatment
Shirato, H., Quynh-Thu Le, Kobashi, K., Prayongrat, A., Takao, S., Shimizu, S., … Umegaki, K. (2018). Selection of external beam radiotherapy approaches for precise and accurate cancer treatment. JOURNAL OF RADIATION RESEARCH, 59, I2–I10. -
Current State of PCR-Based Epstein-Barr Virus DNA Testing for Nasopharyngeal Cancer
Kim, K. Y., Le, Q.-T., Yom, S. S., Pinsky, B. A., Bratman, S. V., Ng, R. H. W., … Conley, B. A. (2017). Current State of PCR-Based Epstein-Barr Virus DNA Testing for Nasopharyngeal Cancer. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 109(4). -
Comprehensive Analysis of the Unfolded Protein Response in Breast Cancer Subtypes.
Jiang, D., Turner, B., Song, J., Li, R., Diehn, M., Le, Q.-T., … Koong, A. C. (2017). Comprehensive Analysis of the Unfolded Protein Response in Breast Cancer Subtypes. JCO Precision Oncology, 2017. -
In Regard to Beadle and Anderson.
Le, Q.-T., Yom, S. S., Wee, J. T., Lee, A. W., Grau, C., Gregoire, V., … Mehanna, H. (2018). In Regard to Beadle and Anderson. International Journal of Radiation Oncology, Biology, Physics, 102(1), 229–30. -
Characteristics of Radiotherapy Trials Compared With Other Oncological Clinical Trials in the Past 10 Years
Liu, X., Zhang, Y., Tang, L.-L., Quynh Thu Le, Chua, M. L. K., Wee, J. T. S., … Ma, J. (2018). Characteristics of Radiotherapy Trials Compared With Other Oncological Clinical Trials in the Past 10 Years. JAMA ONCOLOGY, 4(8), 1073–79. -
Feasibility of optimizing intensity-modulated radiation therapy plans based on measured mucosal dose adjacent to dental fillings and toxicity outcomes
Seol, S. W., Aggarwal, S., von Eyben, R., Wang, Z., Chan, C., Say, C., … Quynh Thu Le. (2018). Feasibility of optimizing intensity-modulated radiation therapy plans based on measured mucosal dose adjacent to dental fillings and toxicity outcomes. JOURNAL OF APPLIED CLINICAL MEDICAL PHYSICS, 19(5), 444–52. -
Delineation of the neck node levels for head and neck tumors: A 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines
Gregoire, V., Ang, K., Budach, W., Grau, C., Hamoir, M., Langendijk, J. A., … Lengele, B. (2014). Delineation of the neck node levels for head and neck tumors: A 2013 update. DAHANCA, EORTC, HKNPCSG, NCIC CTG, NCRI, RTOG, TROG consensus guidelines. RADIOTHERAPY AND ONCOLOGY, 110(1), 172–81. -
Failure of Further Validation for Survival Nomograms in Oropharyngeal Cancer
Fakhry, C., Phuc Felix Nguyen-Tan, Lambert, L., Rosenthal, D. I., Weber, R. S., Gillison, M. L., … Quynh-Thu Le. (2018). Failure of Further Validation for Survival Nomograms in Oropharyngeal Cancer. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 102(3), 669–70. -
Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis.
Xiang, M., Holsinger, F. C., Colevas, A. D., Chen, M. M., Le, Q.-T., & Beadle, B. M. (2018). Survival of patients with head and neck cancer treated with definitive radiotherapy and concurrent cisplatin or concurrent cetuximab: A Surveillance, Epidemiology, and End Results-Medicare analysis. Cancer. -
A pooled analysis of individual patient data from National Clinical Trials Network clinical trials of concurrent chemoradiotherapy for limited-stage small cell lung cancer in elderly patients versus younger patients.
Stinchcombe, T. E., Fan, W., Schild, S. E., Vokes, E. E., Bogart, J., Le, Q.-T., … Wang, X. (2018). A pooled analysis of individual patient data from National Clinical Trials Network clinical trials of concurrent chemoradiotherapy for limited-stage small cell lung cancer in elderly patients versus younger patients. Cancer. -
Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism
Benej, M., Hong, X., Vibhute, S., Scott, S., Wu, J., Graves, E., … Denko, N. C. (2018). Papaverine and its derivatives radiosensitize solid tumors by inhibiting mitochondrial metabolism. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115(42), 10756–61. -
Focus on the Number of Radiation Oncology Trials or on Clinical Relevance-Reply.
Liu, X., Le, Q. T., & Ma, J. (2018). Focus on the Number of Radiation Oncology Trials or on Clinical Relevance-Reply. JAMA Oncology. -
Clinical Outcomes in Elderly Patients Treated for Oral Cavity Squamous Cell Carcinoma
Chen, J. J., Shah, J. L., Harris, J. P., Bui, T. T., Schaberg, K., Kong, C. S., … Hara, W. Y. (2017). Clinical Outcomes in Elderly Patients Treated for Oral Cavity Squamous Cell Carcinoma. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 98(4), 775–83. -
Adaptive radiotherapy for head and neck cancer: Are we ready to put it into routine clinical practice?
Gensheimer, M. F., & Le, Q.-T. (2018). Adaptive radiotherapy for head and neck cancer: Are we ready to put it into routine clinical practice? Oral Oncology, 86, 19–24. -
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial.
Gillison, M. L., Trotti, A. M., Harris, J., Eisbruch, A., Harari, P. M., Adelstein, D. J., … Le, Q. T. (2018). Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial. Lancet (London, England). -
The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy.
Starkov, P., Aguilera, T. A., Golden, D. I., Shultz, D. B., Trakul, N., Maxim, P. G., … Rubin, D. L. (2018). The use of texture-based radiomics CT analysis to predict outcomes in early-stage non-small cell lung cancer treated with stereotactic ablative radiotherapy. The British Journal of Radiology, 20180228. -
SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells
Ozawa, H., Ranaweera, R. S., Izumchenko, E., Makarev, E., Zhavoronkov, A., Fertig, E. J., … Chung, C. H. (2017). SMAD4 Loss Is Associated with Cetuximab Resistance and Induction of MAPK/JNK Activation in Head and Neck Cancer Cells. CLINICAL CANCER RESEARCH, 23(17), 5162–75. -
Increased Galectin-1 Expression in Thymic Epithelial Tumors.
Riess, J. W., Kong, C. S., West, R. B., Padda, S. K., Neal, J. W., Wakelee, H. A., & Le, Q.-T. (2018). Increased Galectin-1 Expression in Thymic Epithelial Tumors. Clinical Lung Cancer. -
Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States.
Harris, J. P., Saraswathula, A., Kaplun, B., Qian, Y., Chan, K. C., Chan, A. T., … Pollom, E. (2019). Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery, 194599819832593. -
Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials.
Fakhry, C., Zhang, Q., Gillison, M. L., Nguyen-Tan, P. F., Rosenthal, D. I., Weber, R. S., … Le, Q.-T. (2019). Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials. Cancer. -
Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy.
Thu Le, Q., Dimitrios Colevas, A., O'Sullivan, B., Lee, A. W., Lee, N., Ma, B., … Malik, S. (2019). Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy. Journal of the National Cancer Institute. -
Integrating tumor and nodal imaging characteristics at baseline and mid-treatment CT scans to predict distant metastasis in oropharyngeal cancer treated with concurrent chemoradiotherapy.
Wu, J., Gensheimer, M. F., Zhang, N., Han, F., Liang, R., Qian, Y., … Li, R. (2019). Integrating tumor and nodal imaging characteristics at baseline and mid-treatment CT scans to predict distant metastasis in oropharyngeal cancer treated with concurrent chemoradiotherapy. International Journal of Radiation Oncology, Biology, Physics. -
Future cancer research priorities in the USA: a Lancet Oncology Commission.
Jaffee, E. M., Dang, C. V., Agus, D. B., Alexander, B. M., Anderson, K. C., Ashworth, A., … Yung, A. (2017). Future cancer research priorities in the USA: a Lancet Oncology Commission. The Lancet. Oncology, 18(11), e653–e706. -
Clinical Utility of Epstein-Barr Virus DNA Testing in the Treatment of Nasopharyngeal Carcinoma Patients.
Kim, K. Y., Le, Q.-T. T., Yom, S. S., Ng, R. H., Chan, K. C., Bratman, S. V., … Conley, B. A. (2017). Clinical Utility of Epstein-Barr Virus DNA Testing in the Treatment of Nasopharyngeal Carcinoma Patients. International Journal of Radiation Oncology, Biology, Physics, 98(5), 996–1001. -
Formation of an international intergroup to coordinate clinical trials in head and neck cancers: HNCIG.
Le, Q. T., Welch, J. J., Vermorken, J. B., Rischin, D., & Mehanna, H. (2017). Formation of an international intergroup to coordinate clinical trials in head and neck cancers: HNCIG. Oral Oncology, 71, 180–183. -
Overview of Advances in Head and Neck Cancer.
Rischin, D., Ferris, R. L., & Le, Q.-T. T. (2015). Overview of Advances in Head and Neck Cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 33(29), 3225–6. -
Individualizing treatment for patients with nasopharyngeal cancer.
Hara, W., & Le, Q.-T. T. (2015). Individualizing treatment for patients with nasopharyngeal cancer. Cancer, 121(16), 2671–3. -
Acceler-dated fractionation: the end of the era of the large, "one size fits all" trial for locally advanced head and neck cancer.
Le, Q.-T. T., & Machtay, M. (2014). Acceler-dated fractionation: the end of the era of the large, "one size fits all" trial for locally advanced head and neck cancer. International Journal of Radiation Oncology, Biology, Physics, 89(1), 7–9. -
Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer: ASCO Provisional Clinical Opinion.
Adelstein, D. J., Ismaila, N., Ku, J. A., Burtness, B., Swiecicki, P. L., Mell, L., … Ridge, J. A. (2019). Role of Treatment Deintensification in the Management of p16+ Oropharyngeal Cancer: ASCO Provisional Clinical Opinion. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO1900441. -
Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial
Gillison, M. L., Trotti, A. M., Harris, J., Eisbruch, A., Harari, P. M., Adelstein, D. J., … Quynh Thu Le. (2019). Radiotherapy plus cetuximab or cisplatin in human papillomavirus-positive oropharyngeal cancer (NRG Oncology RTOG 1016): a randomised, multicentre, non-inferiority trial. LANCET, 393(10166), 40–50. -
Increased Galectin-1 Expression in Thymic Epithelial Tumors
Riess, J. W., Kong, C. S., West, R. B., Padda, S. K., Neal, J. W., Wakelee, H. A., & Le, Q.-T. (2019). Increased Galectin-1 Expression in Thymic Epithelial Tumors. CLINICAL LUNG CANCER, 20(3), E356–E361. -
Nasopharyngeal carcinoma.
Chen, Y.-P., Chan, A. T., Le, Q.-T., Blanchard, P., Sun, Y., & Ma, J. (2019). Nasopharyngeal carcinoma. Lancet (London, England). -
The changing therapeutic landscape of head and neck cancer.
Cramer, J. D., Burtness, B., Le, Q. T., & Ferris, R. L. (2019). The changing therapeutic landscape of head and neck cancer. Nature Reviews. Clinical Oncology. -
Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials
Fakhry, C., Zhang, Q., Gillison, M. L., Nguyen-Tan, P. F., Rosenthal, D. I., Weber, R. S., … Quynh-Thu Le. (2019). Validation of NRG oncology/RTOG-0129 risk groups for HPV-positive and HPV-negative oropharyngeal squamous cell cancer: Implications for risk-based therapeutic intensity trials. CANCER, 125(12), 2027–38. -
Integrating Tumor and Nodal Imaging Characteristics at Baseline and Mid-Treatment Computed Tomography Scans to Predict Distant Metastasis in Oropharyngeal Cancer Treated With Concurrent Chemoradiotherapy
Wu, J., Gensheimer, M. F., Zhang, N., Han, F., Liang, R., Qian, Y., … Li, R. (2019). Integrating Tumor and Nodal Imaging Characteristics at Baseline and Mid-Treatment Computed Tomography Scans to Predict Distant Metastasis in Oropharyngeal Cancer Treated With Concurrent Chemoradiotherapy. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 104(4), 942–52. -
International Guideline on Dose Prioritization and Acceptance Criteria in Radiotherapy Planning for Nasopharyngeal Carcinoma.
Lee, A. W., Ng, W. T., Pan, J. J., Chiang, C.-L., Poh, S. S., Choi, H. C., … Wee, J. T. (2019). International Guideline on Dose Prioritization and Acceptance Criteria in Radiotherapy Planning for Nasopharyngeal Carcinoma. International Journal of Radiation Oncology, Biology, Physics. -
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC).
Cohen, E. E., Bell, R. B., Bifulco, C. B., Burtness, B., Gillison, M. L., Harrington, K. J., … Ferris, R. L. (2019). The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of squamous cell carcinoma of the head and neck (HNSCC). Journal for Immunotherapy of Cancer, 7(1), 184. -
Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States
Harris, J. P., Saraswathula, A., Kaplun, B., Qian, Y., Chan, K. C. A., Chan, A. T. C., … Pollom, E. (2019). Cost-effectiveness of Screening for Nasopharyngeal Carcinoma among Asian American Men in the United States. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 161(1), 82–90. -
Radiographic Extranodal Extension in Human Papillomavirus-Associated Oropharyngeal Carcinoma: Can it Help Tailor Treatment?
Gensheimer, M. F., & Le, Q.-T. (2019). Radiographic Extranodal Extension in Human Papillomavirus-Associated Oropharyngeal Carcinoma: Can it Help Tailor Treatment? International Journal of Radiation Oncology, Biology, Physics, 104(5), 1028–29. -
Role of Treatment Deintensification in the Management of p16+Oropharyngeal Cancer: ASCO Provisional Clinical Opinion
Adelstein, D. J., Ismaila, N., Ku, J. A., Burtness, B., Swiecicki, P. L., Mell, L., … Ridge, J. A. (2019). Role of Treatment Deintensification in the Management of p16+Oropharyngeal Cancer: ASCO Provisional Clinical Opinion. JOURNAL OF CLINICAL ONCOLOGY, 37(18). -
Role of chemotherapy in 5000 patients with head and neck cancer treated by curative surgery: A subgroup analysis of the meta-analysis of chemotherapy in head and neck cancer.
Dauzier, E., Lacas, B., Blanchard, P., Le, Q.-T. T., Simon, C., Wolf, G., … Pignon, J.-P. P. (2019). Role of chemotherapy in 5000 patients with head and neck cancer treated by curative surgery: A subgroup analysis of the meta-analysis of chemotherapy in head and neck cancer. Oral Oncology, 95, 106–14. -
Tumor Subregion Evolution-based Imaging Features to Assess Early Response and Predict Prognosis in Oropharyngeal Cancer.
Wu, J., Gensheimer, M., Zhang, N., Guo, M., Liang, R., Zhang, C., … Li, R. (2019). Tumor Subregion Evolution-based Imaging Features to Assess Early Response and Predict Prognosis in Oropharyngeal Cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. -
Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer.
Mell, L. K., Shen, H., Nguyen-Tan, P. F., Rosenthal, D. I., Zakeri, K., Vitzthum, L. K., … Le, Q.-T. (2019). Nomogram to Predict the Benefit of Intensive Treatment for Locoregionally Advanced Head and Neck Cancer. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition.
Wu, P.-H. H., Onodera, Y., Recuenco, F. C., Giaccia, A. J., Le, Q.-T. T., Shimizu, S., … Nam, J.-M. M. (2019). Lambda-Carrageenan Enhances the Effects of Radiation Therapy in Cancer Treatment by Suppressing Cancer Cell Invasion and Metastasis through Racgap1 Inhibition. Cancers, 11(8). -
Survival After Definitive Chemoradiotherapy With Concurrent Cisplatin or Carboplatin for Head and Neck Cancer.
Xiang, M., Colevas, A. D., Holsinger, F. C., Le, Q.-T. X., & Beadle, B. M. (2019). Survival After Definitive Chemoradiotherapy With Concurrent Cisplatin or Carboplatin for Head and Neck Cancer. Journal of the National Comprehensive Cancer Network : JNCCN, 17(9), 1065–73. -
Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy
Le, Q. T., Colevas, A. D., OSullivan, B., Lee, A. W. M., Lee, N., Ma, B., … Malik, S. (2019). Current Treatment Landscape of Nasopharyngeal Carcinoma and Potential Trials Evaluating the Value of Immunotherapy. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 111(7), 655–63. -
Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance.
Nambiar, D. K., Aguilera, T., Cao, H., Kwok, S., Kong, C., Bloomstein, J., … Le, Q. T. (2019). Galectin-1-driven T cell exclusion in the tumor endothelium promotes immunotherapy resistance. The Journal of Clinical Investigation. -
Proton radiotherapy and treatment delay in head and neck squamous cell carcinoma.
Jin, M. C., Harris, J. P., Sabolch, A. N., Gensheimer, M., Le, Q.-T., Beadle, B. M., & Pollom, E. L. (2019). Proton radiotherapy and treatment delay in head and neck squamous cell carcinoma. The Laryngoscope. -
Comments on the Publication by Corkum etal on "Does 5 + 5mm Equal Better Radiation Treatment Plans in Head and Neck Cancers?"
Gregoire, V., Grau, C., Le, Q.-T., & Yom, S. S. (2020). Comments on the Publication by Corkum etal on "Does 5 + 5mm Equal Better Radiation Treatment Plans in Head and Neck Cancers?". Advances in Radiation Oncology, 5(1), 140–41. -
The role of Glial cell derived neurotrophic factor in head and neck cancer.
Cao, H., He, Q., Eyben, R. von, Bloomstein, J., Nambiar, D. K., Viswanathan, V., … Le, Q.-T. (2020). The role of Glial cell derived neurotrophic factor in head and neck cancer. PloS One, 15(2), e0229311. -
Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations.
Aguilera, T. A., Elghonaimy, E., Shehade, H., Rafat, M., Castellini, L., Jiang, D., … Giaccia, A. J. (2020). Induced tumor heterogeneity reveals factors informing radiation and immunotherapy combinations. Clinical Cancer Research : an Official Journal of the American Association for Cancer Research. -
Retraction Note: Lysyl oxidase is essential for hypoxia-induced metastasis.
Erler, J. T., Bennewith, K. L., Nicolau, M., Dornhofer, N., Kong, C., Le, Q.-T., … Giaccia, A. J. (2020). Retraction Note: Lysyl oxidase is essential for hypoxia-induced metastasis. Nature, 579(7799), 456. -
Head and Neck Cancer International Group (HNCIG) Consensus Guidelines for the delivery of postoperative radiation therapy in complex cutaneous squamous cell carcinoma of the head and neck (cSCCHN).
Porceddu, S. V., Daniels, C., Yom, S. S., Liu, H., Waldron, J., Gregoire, V., … Le, Q.-T. (2020). Head and Neck Cancer International Group (HNCIG) Consensus Guidelines for the delivery of postoperative radiation therapy in complex cutaneous squamous cell carcinoma of the head and neck (cSCCHN). International Journal of Radiation Oncology, Biology, Physics. -
Understanding High-Dose, Ultra-High Dose-Rate and , Spatially Fractionated Radiotherapy.
Griffin, R. J., Ahmed, M. M., Amendola, B., Belyakov, O., Bentzen, S. M., Butterworth, K. T., … Limoli, C. L. (2020). Understanding High-Dose, Ultra-High Dose-Rate and , Spatially Fractionated Radiotherapy. International Journal of Radiation Oncology, Biology, Physics. -
Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: an ASTRO-ESTRO consensus statement.
Thomson, D. J., Palma, D., Guckenberger, M., Balermpas, P., Beitler, J. J., Blanchard, P., … Yom, S. S. (2020). Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: an ASTRO-ESTRO consensus statement. International Journal of Radiation Oncology, Biology, Physics. -
De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies.
Mehanna, H., Rischin, D., Wong, S. J., Gregoire, V., Ferris, R., Waldron, J., … Porceddu, S. (2020). De-Escalation After DE-ESCALATE and RTOG 1016: A Head and Neck Cancer InterGroup Framework for Future De-Escalation Studies. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2000056. -
Pilot study of loss of the p53/p63 target genePERPat the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma
Holmes, B. J., von Eyben, R., Attardi, L. D., Kong, C. S., Le, Q.-T., & Nathan, C.-A. O. (2020). Pilot study of loss of the p53/p63 target genePERPat the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK. -
Reprint of: Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: An ASTRO-ESTRO consensus statement.
Thomson, D. J., Palma, D., Guckenberger, M., Balermpas, P., Beitler, J. J., Blanchard, P., … Yom, S. S. (2020). Reprint of: Practice recommendations for risk-adapted head and neck cancer radiotherapy during the COVID-19 pandemic: An ASTRO-ESTRO consensus statement. Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. -
Resection following concurrent chemotherapy and high-dose radiation for stage IIIA non-small cell lung cancer.
Donington, J. S., Paulus, R., Edelman, M. J., Krasna, M. J., Le, Q.-T., Suntharalingam, M., … Bradley, J. D. (2020). Resection following concurrent chemotherapy and high-dose radiation for stage IIIA non-small cell lung cancer. The Journal of Thoracic and Cardiovascular Surgery. -
Multicenter Clinical Cancer Research After COVID-19: A Perspective From NRG Oncology.
Gensheimer, M. F., Yom, S. S., Soto, N., Dignam, J. J., Le, Q.-T., Machtay, M., & Curran, W. J. (2020). Multicenter Clinical Cancer Research After COVID-19: A Perspective From NRG Oncology. International Journal of Radiation Oncology, Biology, Physics, 108(2), 483–85. -
Predictive classifier for intensive treatment of head and neck cancer.
Zakeri, K., Rotolo, F., Lacas, B., Vitzthum, L. K., Le, Q.-T. T., Gregoire, V., … Mell, L. K. (2020). Predictive classifier for intensive treatment of head and neck cancer. Cancer. -
Pilot study of loss of the p53/p63 target gene PERP at the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma.
Holmes, B. J., von Eyben, R., Attardi, L. D., Kong, C. S., Le, Q.-T. T., & Nathan, C.-A. O. (2020). Pilot study of loss of the p53/p63 target gene PERP at the surgical margin as a potential predictor of local relapse in head and neck squamous cell carcinoma. Head & Neck. -
18 FDG PET/CT prediction of treatment outcomes in patients with p16-positive, non-smoking associated, locoregionally advanced oropharyngeal cancer (LAOPC) receiving deintensified therapy: Results from NRG-HN002.
Subramaniam, R. M., Demora, L., Yao, M., Yom, S. S., Gillison, M. L., Caudell, J. J., … Le, Q.-T. (2020). 18 FDG PET/CT prediction of treatment outcomes in patients with p16-positive, non-smoking associated, locoregionally advanced oropharyngeal cancer (LAOPC) receiving deintensified therapy: Results from NRG-HN002. JOURNAL OF CLINICAL ONCOLOGY, 38(15). -
Lysosomal trafficking mediated by Arl8b and BORC promotes invasion of cancer cells that survive radiation.
Wu, P.-H. H., Onodera, Y., Giaccia, A. J., Le, Q.-T. T., Shimizu, S., Shirato, H., & Nam, J.-M. M. (2020). Lysosomal trafficking mediated by Arl8b and BORC promotes invasion of cancer cells that survive radiation. Communications Biology, 3(1), 620. -
Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer.
Tailor, D., Going, C. C., Resendez, A., Kumar, V., Nambiar, D. K., Li, Y., … Malhotra, S. V. (2020). Novel Aza-podophyllotoxin derivative induces oxidative phosphorylation and cell death via AMPK activation in triple-negative breast cancer. British Journal of Cancer. -
Cost-Effectiveness of Nasopharyngeal Carcinoma Screening with Epstein-Barr Virus Polymerase Chain Reaction or Serology in High-Incidence Populations Worldwide.
Miller, J. A., Le, Q.-T., Pinsky, B. A., & Wang, H. (2020). Cost-Effectiveness of Nasopharyngeal Carcinoma Screening with Epstein-Barr Virus Polymerase Chain Reaction or Serology in High-Incidence Populations Worldwide. Journal of the National Cancer Institute. -
Prolongation of definitive head and neck cancer radiotherapy: Survival impact and predisposing factors.
Xiang, M., Gensheimer, M. F., Pollom, E. L., Holsinger, F. C., Colevas, A. D., Le, Q.-T. T., & Beadle, B. M. (2020). Prolongation of definitive head and neck cancer radiotherapy: Survival impact and predisposing factors. Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology. -
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy.
Lechner, M., Schartinger, V. H., Steele, C. D., Nei, W. L., Ooft, M. L., Schreiber, L.-M., … Lund, V. J. (2021). Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy. Nature Communications, 12(1), 117. -
Rab27b contributes to radioresistance and exerts a paracrine effect via epiregulin in glioblastoma.
Nishioka, S., Wu, P.-H., Yakabe, T., Giaccia, A. J., Le, Q.-T., Aoyama, H., … Nam, J.-M. (2020). Rab27b contributes to radioresistance and exerts a paracrine effect via epiregulin in glioblastoma. Neuro-Oncology Advances, 2(1), vdaa091. -
Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline.
Chen, Y.-P., Ismaila, N., Chua, M. L., Colevas, A. D., Haddad, R., Huang, S. H., … Ma, J. (2021). Chemotherapy in Combination With Radiotherapy for Definitive-Intent Treatment of Stage II-IVA Nasopharyngeal Carcinoma: CSCO and ASCO Guideline. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2003237. -
Postoperative Observation Versus Radiotherapy for Pathologic N1 Oral Cavity Squamous Cell Carcinoma.
Xiang, M., Holsinger, F. C., Gensheimer, M. F., Divi, V., Pollom, E. L., Colevas, A. D., … Beadle, B. M. (2021). Postoperative Observation Versus Radiotherapy for Pathologic N1 Oral Cavity Squamous Cell Carcinoma. American Journal of Clinical Oncology, Publish Ahead of Print. -
Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002).
Yom, S. S., Torres-Saavedra, P., Caudell, J. J., Waldron, J. N., Gillison, M. L., Xia, P., … Le, Q.-T. T. (2021). Reduced-Dose Radiation Therapy for HPV-Associated Oropharyngeal Carcinoma (NRG Oncology HN002). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2003128. -
International Recommendations on Re-irradiation by Intensity-modulated Radiotherapy for Locally Recurrent Nasopharyngeal Carcinoma.
Ng, W. T., Soong, Y. L., Chan Ahn, Y., AlHussain, H., Choi, H. C., Corry, J., … Lee, A. W. (2021). International Recommendations on Re-irradiation by Intensity-modulated Radiotherapy for Locally Recurrent Nasopharyngeal Carcinoma. International Journal of Radiation Oncology, Biology, Physics. -
Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores - A pooled analysis of RTOG 0129 and 0522.
Awan, M. J., Gittleman, H., Barnholtz-Sloan, J., Machtay, M., Nguyen-Tan, P. F., Rosenthal, D. I., … Yao, M. (2021). Risk groups of laryngeal cancer treated with chemoradiation according to nomogram scores - A pooled analysis of RTOG 0129 and 0522. Oral Oncology, 116, 105241. -
Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer.
Tailor, D., Resendez, A., Garcia-Marques, F. J., Pandrala, M., Going, C. C., Bermudez, A., … Malhotra, S. V. (2021). Y box binding protein 1 inhibition as a targeted therapy for ovarian cancer. Cell Chemical Biology. -
The impact of age on outcome in phase III NRG Oncology/RTOG trials of radiotherapy (XRT) +/- systemic therapy in locally advanced head and neck cancer.
Kish, J. A., Zhang, Q., Langer, C. J., Nguyen-Tan, P. F., Rosenthal, D. I., Weber, R. S., … Le, Q.-T. (2021). The impact of age on outcome in phase III NRG Oncology/RTOG trials of radiotherapy (XRT) +/- systemic therapy in locally advanced head and neck cancer. Journal of Geriatric Oncology. -
Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis.
Petit, C., Lacas, B., Pignon, J.-P. P., Le, Q. T., Grégoire, V., Grau, C., … Blanchard, P. (2021). Chemotherapy and radiotherapy in locally advanced head and neck cancer: an individual patient data network meta-analysis. The Lancet. Oncology. -
Evaluation of Oncology Trial Results Reporting Over a 10-Year Period.
Liu, X., Zhang, Y., Li, W.-F., Vokes, E., Sun, Y., Le, Q.-T., & Ma, J. (2021). Evaluation of Oncology Trial Results Reporting Over a 10-Year Period. JAMA Network Open, 4(5), e2110438. -
Reply to A. Cmelak et al and B. Kalra et al.
Yom, S. S., Torres-Saavedra, P. A., & Le, Q.-T. T. (2021). Reply to A. Cmelak et al and B. Kalra et al. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, JCO2100882. -
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models.
Mehibel, M., Xu, Y., Li, C. G., Moon, E. J., Thakkar, K. N., Diep, A. N., … Giaccia, A. J. (2021). Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination-deficient cancer models. The Journal of Clinical Investigation, 131(11). -
Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination & ndash;deficient cancer models
Mehibel, M., Xu, Y., Li, C. G., Moon, E. J., Thakkar, K. N., Diep, A. N., … Giaccia, A. J. (2021). Eliminating hypoxic tumor cells improves response to PARP inhibitors in homologous recombination & ndash;deficient cancer models. JOURNAL OF CLINICAL INVESTIGATION, 131(11). -
NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer
Bauman, J. E., Harris, J., Uppaluri, R., Yao, M., Ferris, R. L., Chen, J., … Quynh-Thu Le. (2021). NRG-HN003: Phase I and Expansion Cohort Study of Adjuvant Pembrolizumab, Cisplatin and Radiation Therapy in Pathologically High-Risk Head and Neck Cancer. CANCERS, 13(12). -
Risk stratification after recurrence of human papillomavirus (HPV)-related and non-HPV-related oropharyngeal cancer: A secondary analysis of NRG Oncology RTOG 0129 and 0522.
Bigelow, E. O., Harris, J., Fakhry, C., Gillison, M. L., Nguyen-Tan, P. F., Rosenthal, D. I., … Le, Q.-T. (2021). Risk stratification after recurrence of human papillomavirus (HPV)-related and non-HPV-related oropharyngeal cancer: A secondary analysis of NRG Oncology RTOG 0129 and 0522. Head & Neck. -
NRG Oncology HN006: Randomized phase II/III trial of sentinel lymph node biopsy versus elective neck dissection for early-stage oral cavity cancer.
Lai, S. Y., Torres-Saavedra, P. A., Dunlap, N. E., Beadle, B. M., Chang, S. S., Subramaniam, R. M., … Le, Q.-T. (2021). NRG Oncology HN006: Randomized phase II/III trial of sentinel lymph node biopsy versus elective neck dissection for early-stage oral cavity cancer. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
JUPITER-02 trial: advancing survival for recurrent metastatic nasopharyngeal carcinoma and next steps.
Tan, L. L., Le, Q.-T., Lee, N. Y., & Chua, M. L. (1800). JUPITER-02 trial: advancing survival for recurrent metastatic nasopharyngeal carcinoma and next steps. Cancer Communications (London, England). -
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma.
Lechner, M., Takahashi, Y., Turri-Zanoni, M., Liu, J., Counsell, N., Hermsen, M., … Hanna, E. Y. (1800). Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma. European Journal of Cancer (Oxford, England : 1990). -
An International Consensus on the Design of Prospective Clinical-Translational Trials in Spatially Fractionated Radiation Therapy.
Mayr, N. A., Snider, J. W., Regine, W. F., Mohiuddin, M., Hippe, D. S., Penagaricano, J., … Simone, C. B. (2022). An International Consensus on the Design of Prospective Clinical-Translational Trials in Spatially Fractionated Radiation Therapy. Advances in Radiation Oncology, 7(2), 100866. -
De-escalating elective nodal irradiation for nasopharyngeal carcinoma.
Miller, J. A., Beadle, B. M., Gensheimer, M. F., & Le, Q.-T. (2022). De-escalating elective nodal irradiation for nasopharyngeal carcinoma. The Lancet. Oncology. -
The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-?B signaling.
Tay, J. K., Zhu, C., Shin, J. H., Zhu, S. X., Varma, S., Foley, J. W., … West, R. B. (2022). The microdissected gene expression landscape of nasopharyngeal cancer reveals vulnerabilities in FGF and noncanonical NF-?B signaling. Science Advances, 8(14), eabh2445. -
Nodal Metastasis Count and Oncologic Outcomes in Head and Neck Cancer: A Secondary Analysis of NRG/RTOG 9501, NRG/RTOG 0234, and EORTC 22931.
Lu, D. J., Luu, M., Gay, C., Nguyen, A. T., Anderson, E. M., Bernier, J., … Zumsteg, Z. S. (2022). Nodal Metastasis Count and Oncologic Outcomes in Head and Neck Cancer: A Secondary Analysis of NRG/RTOG 9501, NRG/RTOG 0234, and EORTC 22931. International Journal of Radiation Oncology, Biology, Physics. -
Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA.
Zhang, W., Li, I., Reticker-Flynn, N. E., Good, Z., Chang, S., Samusik, N., … Plevritis, S. K. (2022). Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA. Nature Methods. -
Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype.
Viswanathan, V., Cao, H., Saiki, J., Jiang, D., Mattingly, A., Nambiar, D., … Le, Q.-T. (2022). Aldehyde dehydrogenase 3A1 deficiency leads to mitochondrial dysfunction and impacts salivary gland stem cell phenotype. PNAS Nexus, 1(2), pgac056. -
National Effort to Re-Establish Heavy Ion Cancer Therapy in the United States.
Pompos, A., Foote, R. L., Koong, A. C., Le, Q. T., Mohan, R., Paganetti, H., & Choy, H. (2022). National Effort to Re-Establish Heavy Ion Cancer Therapy in the United States. Frontiers in Oncology, 12, 880712. -
International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System
Lechner, M., Takahashi, Y., Turri-Zanoni, M., Ferrari, M., Liu, J., Counsell, N., … Hanna, E. Y. (2022). International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System. JOURNAL OF NEUROLOGICAL SURGERY PART B-SKULL BASE. -
Multiplex Epstein-Barr virus BALF2 genotyping detects high-risk variants in plasma for population screening of nasopharyngeal carcinoma.
Miller, J. A., Sahoo, M. K., Yamamoto, F., Huang, C. H., Wang, H., Zehnder, J. L., … Pinsky, B. A. (2022). Multiplex Epstein-Barr virus BALF2 genotyping detects high-risk variants in plasma for population screening of nasopharyngeal carcinoma. Molecular Cancer, 21(1), 154. -
Posttreatment FDG-PET/CT Hopkins criteria predict locoregional recurrence after definitive radiotherapy for oropharyngeal squamous cell carcinoma.
Miller, J. A., Moradi, F., Sundaram, V., Liang, R., Zhang, C., Nguyen, N. K., … Gensheimer, M. F. (2022). Posttreatment FDG-PET/CT Hopkins criteria predict locoregional recurrence after definitive radiotherapy for oropharyngeal squamous cell carcinoma. Head & Neck. -
The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer.
Sodji, Q. H., Nambiar, D. K., Viswanathan, V., von Eyben, R., Colburg, D., Binkley, M. S., … Giaccia, A. J. (2022). The Combination of Radiotherapy and Complement C3a Inhibition Potentiates Natural Killer cell Functions Against Pancreatic Cancer. Cancer Research Communications, 2(7), 725–738. -
Evolutionary Action Score of TP53 Analysis in Pathologically High-Risk Human Papillomavirus-Negative Head and Neck Cancer From a Phase 2 Clinical Trial: NRG Oncology Radiation Therapy Oncology Group 0234
Michikawa, C., Torres-Saavedra, P. A., Silver, N. L., Harari, P. M., Kies, M. S., Rosenthal, D. I., … Myers, J. N. (2022). Evolutionary Action Score of TP53 Analysis in Pathologically High-Risk Human Papillomavirus-Negative Head and Neck Cancer From a Phase 2 Clinical Trial: NRG Oncology Radiation Therapy Oncology Group 0234. ADVANCES IN RADIATION ONCOLOGY, 7(6). -
Nodal Metastasis Count and Oncologic Outcomes in Head and Neck Cancer: A Secondary Analysis of NRG/RTOG 9501, NRG/RTOG 0234, and EORTC 22931
Lu, D. J., Luu, M., Gay, C., Nguyen, A. T., Anderson, E. M., Bernier, J., … Zumsteg, Z. S. (2022). Nodal Metastasis Count and Oncologic Outcomes in Head and Neck Cancer: A Secondary Analysis of NRG/RTOG 9501, NRG/RTOG 0234, and EORTC 22931. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 113(4), 787–795. -
Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma.
Rodriguez, C. P., Kang, H., Geiger, J. L., Burtness, B., Chung, C. H., Pickering, C. R., … Malik, S. (2022). Clinical Trial Development in TP53-Mutated Locally Advanced and Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. Journal of the National Cancer Institute. -
An International Consensus on the Design of Prospective Clinical-Translational Trials in Spatially Fractionated Radiation Therapy for Advanced Gynecologic Cancer
Amendola, B. E., Mahadevan, A., Suarez, J. M. B., Griffin, R. J., Wu, X., Perez, N. C., … Mayr, N. A. (2022). An International Consensus on the Design of Prospective Clinical-Translational Trials in Spatially Fractionated Radiation Therapy for Advanced Gynecologic Cancer. CANCERS, 14(17). -
18F FDG PET/CT Prediction of Treatment Outcomes in HPV-positive, Locally Advanced Oropharyngeal Cancer Receiving De-intensified Therapy: Results from NRG-HN002.
Subramaniam, R. M., DeMora, L., Yao, M., Yom, S. S., Gillison, M., Caudell, J. J., … Le, Q.-T. (2022). 18F FDG PET/CT Prediction of Treatment Outcomes in HPV-positive, Locally Advanced Oropharyngeal Cancer Receiving De-intensified Therapy: Results from NRG-HN002. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. -
Safety of nivolumab added to chemoradiotherapy platforms for intermediate and high-risk local-regionally advanced head and neck squamous cell carcinoma: RTOG Foundation 3504.
Gillison, M. L., Ferris, R. L., Harris, J., Colevas, A. D., Mell, L. K., Kong, C., … Le, Q. T. (2022). Safety of nivolumab added to chemoradiotherapy platforms for intermediate and high-risk local-regionally advanced head and neck squamous cell carcinoma: RTOG Foundation 3504. International Journal of Radiation Oncology, Biology, Physics. -
Association of plasma tumor tissue modified viral HPV DNA (TTMV) with tumor burden, treatment type, and outcome: A translational analysis from NRG-HN002.
Yom, S. S., Torres-Saavedra, P. A., Kuperwasser, C., Kumar, S., Gupta, P. B., Ha, P., … Le, Q.-T. (2022). Association of plasma tumor tissue modified viral HPV DNA (TTMV) with tumor burden, treatment type, and outcome: A translational analysis from NRG-HN002. JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Evolutionary Action Score of TP53 Analysis in Pathologically High-Risk Human Papillomavirus-Negative Head and Neck Cancer From a Phase 2 Clinical Trial: NRG Oncology Radiation Therapy Oncology Group 0234.
Michikawa, C., Torres-Saavedra, P. A., Silver, N. L., Harari, P. M., Kies, M. S., Rosenthal, D. I., … Myers, J. N. (2022). Evolutionary Action Score of TP53 Analysis in Pathologically High-Risk Human Papillomavirus-Negative Head and Neck Cancer From a Phase 2 Clinical Trial: NRG Oncology Radiation Therapy Oncology Group 0234. Advances in Radiation Oncology, 7(6), 100989. -
International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic.
Lee, V. H.-F., Adham, M., Ben Kridis, W., Bossi, P., Chen, M.-Y. Y., Chitapanarux, I., … Wee, J. T. (2022). International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic. The Lancet. Oncology, 23(12), e544–e551. -
Reflections on the 2021 Accreditation Council for Graduate Medical Education and American Board of Radiology Family and Medical Leave of Absence Policies: An Opportunity to Increase Structural Support for Physicians.
Baniel, C. C., Klebaner, D., Beadle, B. M., Ponce, S. E., Takiar, V., Gibbs, I. C., … Pollom, E. L. (2023). Reflections on the 2021 Accreditation Council for Graduate Medical Education and American Board of Radiology Family and Medical Leave of Absence Policies: An Opportunity to Increase Structural Support for Physicians. International Journal of Radiation Oncology, Biology, Physics, 115(1), 19–22. -
Long-term update of NRG/RTOG 0522: a randomized phase III trial of concurrent radiation and cisplatin with or without cetuximab in locoregionally advanced head and neck cancer.
Caudell, J. J., Torres-Saavedra, P. A., Rosenthal, D. I., Axelrod, R. S., Nguyen-Tan, P. F., Sherman, E. J., … Le, Q.-T. (2022). Long-term update of NRG/RTOG 0522: a randomized phase III trial of concurrent radiation and cisplatin with or without cetuximab in locoregionally advanced head and neck cancer. International Journal of Radiation Oncology, Biology, Physics. -
Improving lung cancer screening rates among patients with head and neck cancer in a radiation oncology clinic
Soto, L., Nesbit, S., Ramsey, M., Gensheimer, M. F., Le, Q. T., Beadle, B. M., & Lui, N. S. (2022). Improving lung cancer screening rates among patients with head and neck cancer in a radiation oncology clinic. JOURNAL OF THORACIC DISEASE. -
Improving lung cancer screening rates among patients with head and neck cancer in a radiation oncology clinic.
Soto, L., Nesbit, S., Ramsey, M., Gensheimer, M. F., Le, Q. T., Beadle, B. M., & Lui, N. S. (2022). Improving lung cancer screening rates among patients with head and neck cancer in a radiation oncology clinic. Journal of Thoracic Disease, 14(12), 4633–4640. -
NFE2L2 mutations enhance radioresistance in head and neck cancer by modulating intratumoral myeloid cells.
Guan, L., Nambiar, D. K., Cao, H., Viswanathan, V., Kwok, S., Hui, A. B., … Le, Q.-T. T. (2023). NFE2L2 mutations enhance radioresistance in head and neck cancer by modulating intratumoral myeloid cells. Cancer Research. -
Radiotherapy and paclitaxel plus pazopanib or placebo in anaplastic thyroid cancer (NRG/RTOG 0912): a randomised, double-blind, placebo-controlled, multicentre, phase 2 trial.
Sherman, E. J., Harris, J., Bible, K. C., Xia, P., Ghossein, R. A., Chung, C. H., … Lee, N. Y. (2023). Radiotherapy and paclitaxel plus pazopanib or placebo in anaplastic thyroid cancer (NRG/RTOG 0912): a randomised, double-blind, placebo-controlled, multicentre, phase 2 trial. The Lancet. Oncology. -
Recommendations for Epstein-Barr virus-based screening for nasopharyngeal cancer in high- and intermediate-risk regions.
Lam, W. K., King, A. D., Miller, J. A., Liu, Z., Yu, K. J., Chua, M. L., … Hildesheim, A. (2023). Recommendations for Epstein-Barr virus-based screening for nasopharyngeal cancer in high- and intermediate-risk regions. Journal of the National Cancer Institute. -
In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradiation.
Jun, M., Pinto, H., Le, Q.-T. T., Quon, A., Hara, W., Coty, J., … Colevas, A. D. (2023). In search for optimal induction chemotherapy for advanced nasopharyngeal cancer: Standard dosing of Docetaxel, Platinum, and 5-Fluorouracil (TPF) followed by chemoradiation. PloS One, 18(2), e0276651. -
Utilizing a Culture Committee to Improve and Maintain a Positive Workplace Environment During a Global Pandemic.
Lau, B., Guo, F., Valenton, J., Chang, D., Le, Q.-T., & Horst, K. (2023). Utilizing a Culture Committee to Improve and Maintain a Positive Workplace Environment During a Global Pandemic. Practical Radiation Oncology. -
Final Report of NRG Oncology RTOG 0022: A Phase I/II Study of Conformal and Intensity.
Garden, A. S., Harris, J., Eisbruch, A., Chao, K. S., Morrison, W. H., Harari, P. M., … Le, Q. T. (2023). Final Report of NRG Oncology RTOG 0022: A Phase I/II Study of Conformal and Intensity. International Journal of Radiation Oncology, Biology, Physics. -
Comparison of Real-Time PCR and Digital PCR for Detection of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma.
Miller, J. A., Huang, C. H., Yamamoto, F., Sahoo, M. K., Le, Q.-T., & Pinsky, B. A. (2023). Comparison of Real-Time PCR and Digital PCR for Detection of Plasma Epstein-Barr Virus DNA in Nasopharyngeal Carcinoma. The Journal of Molecular Diagnostics : JMD. -
International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic
Lee, V. H.-F., Adham, M., Ben Kridis, W., Bossi, P., Chen, M.-Y., Chitapanarux, I., … Wee, J. T. (2022). International recommendations for plasma Epstein-Barr virus DNA measurement in nasopharyngeal carcinoma in resource-constrained settings: lessons from the COVID-19 pandemic. LANCET ONCOLOGY, 23(12), E544–E551. -
Long-term Outcomes of Bevacizumab and Chemoradiation for Locoregionally Advanced Nasopharyngeal Carcinoma: A Nonrandomized Controlled Trial.
Lee, N. Y., Harris, J., Kim, J., Garden, A., Mechalakos, J., Pfister, D. G., … Le, Q.-T. (2023). Long-term Outcomes of Bevacizumab and Chemoradiation for Locoregionally Advanced Nasopharyngeal Carcinoma: A Nonrandomized Controlled Trial. JAMA Network Open, 6(6), e2316094. -
Lessons and Opportunities for Biomarker-Driven Radiation Personalization in Head and Neck Cancer.
Rahimy, E., Gensheimer, M. F., Beadle, B., & Le, Q.-T. T. (2023). Lessons and Opportunities for Biomarker-Driven Radiation Personalization in Head and Neck Cancer. Seminars in Radiation Oncology, 33(3), 336–347. -
International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System.
Lechner, M., Takahashi, Y., Turri-Zanoni, M., Ferrari, M., Liu, J., Counsell, N., … Hanna, E. Y. (2023). International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System. Journal of Neurological Surgery. Part B, Skull Base, 84(4), 307–319. -
Galectin-1 mediates chronic STING activation in tumors to promote metastasis through MDSC recruitment.
Nambiar, D. K., Viswanathan, V., Cao, H., Zhang, W., Guan, L., Chamoli, M., … Le, Q.-T. T. (2023). Galectin-1 mediates chronic STING activation in tumors to promote metastasis through MDSC recruitment. Cancer Research. -
Adaptive Region-Specific Loss for Improved Medical Image Segmentation.
Chen, Y., Yu, L., Wang, J.-Y., Panjwani, N., Obeid, J.-P., Liu, W., … Xing, L. (2023). Adaptive Region-Specific Loss for Improved Medical Image Segmentation. IEEE Transactions on Pattern Analysis and Machine Intelligence, PP. -
Hot on the trail in the TME: Clues from a trilogy of checkpoint inhibitor trials in nasopharyngeal cancer
Ma, B. B. Y., & Le, Q. T. (2023). Hot on the trail in the TME: Clues from a trilogy of checkpoint inhibitor trials in nasopharyngeal cancer. CANCER CELL, 41(6), 1006–1008. -
Individualized Stereotactic Ablative Radiotherapy for Lung Tumors: The iSABR Phase 2 Nonrandomized Controlled Trial.
Gensheimer, M. F., Gee, H., Shirato, H., Taguchi, H., Snyder, J. M., Chin, A. L., … Diehn, M. (2023). Individualized Stereotactic Ablative Radiotherapy for Lung Tumors: The iSABR Phase 2 Nonrandomized Controlled Trial. JAMA Oncology. -
Targeted proteomic quantitation of NRF2 signaling and predictive biomarkers in HNSCC.
Wamsley, N. T., Wilkerson, E. M., Guan, L., LaPak, K. M., Schrank, T. P., Holmes, B. J., … Ben Major, M. (2023). Targeted proteomic quantitation of NRF2 signaling and predictive biomarkers in HNSCC. Molecular & Cellular Proteomics : MCP, 100647. -
Association between locoregional failure and NFE2L2/KEAP1/CUL3 pathway mutations in NRG/RTOG 9512: A randomized trial of hyperfractionation vs. conventional fractionation in T2N0 glottic squamous cell carcinoma (SCC).
Guan, L., Torres-Saavedra, P. A., Zhao, X., Major, M. B., Holmes, B. J., Nguyen, N., … Hayes, D. N. (2023). Association between locoregional failure and NFE2L2/KEAP1/CUL3 pathway mutations in NRG/RTOG 9512: A randomized trial of hyperfractionation vs. conventional fractionation in T2N0 glottic squamous cell carcinoma (SCC). JOURNAL OF CLINICAL ONCOLOGY. LIPPINCOTT WILLIAMS & WILKINS. -
Radiotherapy Plus Cisplatin With or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial.
Wong, S. J., Torres-Saavedra, P. A., Saba, N. F., Shenouda, G., Bumpous, J. M., Wallace, R. E., … Le, Q.-T. T. (2023). Radiotherapy Plus Cisplatin With or Without Lapatinib for Non-Human Papillomavirus Head and Neck Carcinoma: A Phase 2 Randomized Clinical Trial. JAMA Oncology. -
Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1.
Beach, C., MacLean, D., Majorova, D., Melemenidis, S., Nambiar, D. K., Kim, R. K., … Olcina, M. M. (2023). Improving radiotherapy in immunosuppressive microenvironments by targeting complement receptor C5aR1. The Journal of Clinical Investigation. -
Season of radiotherapy and outcomes of head & neck cancer patients in the MACH-NC & MARCH meta-analyses.
Limkin, E., Blanchard, P., Lacas, B., Bourhis, J., Parmar, M., Licitra, L., … Auperin, A. (2023). Season of radiotherapy and outcomes of head & neck cancer patients in the MACH-NC & MARCH meta-analyses. Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 110011. -
Cancer Informatics for Cancer Centers: Sharing Ideas on How to Build an Artificial Intelligence-Ready Informatics Ecosystem for Radiation Oncology.
Bitterman, D. S., Gensheimer, M. F., Jaffray, D., Pryma, D. A., Jiang, S. B., Morin, O., … Kibbe, W. (2023). Cancer Informatics for Cancer Centers: Sharing Ideas on How to Build an Artificial Intelligence-Ready Informatics Ecosystem for Radiation Oncology. JCO Clinical Cancer Informatics, 7, e2300136. -
Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer.
Ko, R. B., Abelson, J. A., Fleischmann, D., Louie, J. D., Hwang, G. L., Sze, D. Y., … Loo, B. W. (2023). Pulmonary interstitial lymphography: A prospective trial with potential impact on stereotactic ablative radiotherapy planning for early-stage lung cancer. Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 110079. -
First-Year Experience of Stereotactic Body Radiation Therapy/Intensity Modulated Radiation Therapy Treatment Using a Novel Biology-Guided Radiation Therapy Machine.
Shi, M., Simiele, E., Han, B., Pham, D., Palomares, P., Aguirre, M., … Kovalchuk, N. (2024). First-Year Experience of Stereotactic Body Radiation Therapy/Intensity Modulated Radiation Therapy Treatment Using a Novel Biology-Guided Radiation Therapy Machine. Advances in Radiation Oncology, 9(1), 101300. -
The lipid-binding D4 domain of perfringolysin O facilitates the active loading of exogenous cargo into extracellular vesicles.
Opadele, A. E., Nishioka, S., Wu, P.-H., Le, Q.-T., Shirato, H., Nam, J.-M., & Onodera, Y. (2024). The lipid-binding D4 domain of perfringolysin O facilitates the active loading of exogenous cargo into extracellular vesicles. FEBS Letters. -
Surrogate endpoints in clinical trials of p16-positive squamous cell carcinoma of the oropharynx: an individual patient data meta-analysis.
Gharzai, L. A., Morris, E., Suresh, K., Nguyen-Tân, P. F., Rosenthal, D. I., Gillison, M. L., … Schipper, M. J. (2024). Surrogate endpoints in clinical trials of p16-positive squamous cell carcinoma of the oropharynx: an individual patient data meta-analysis. The Lancet. Oncology, 25(3), 366–375. -
Optimization and Local Cost-Effectiveness of Nasopharyngeal Carcinoma Screening Strategies in Southern China: Secondary Analysis of the Guangdong Randomized Trial.
Miller, J. A., Liu, Z., Pinsky, B. A., Le, Q.-T., Li, T., Yu, K. J., … Cao, S.-M. (2024). Optimization and Local Cost-Effectiveness of Nasopharyngeal Carcinoma Screening Strategies in Southern China: Secondary Analysis of the Guangdong Randomized Trial. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology. -
The Assistant Clinical Research Coordinator Program: A Pathway for Recruitment in Radiation Oncology.
Aboytes, M., Cody, M., Laseinde, E., Hall, J., Soltys, S., Beadle, B., … Pollom, E. L. (2024). The Assistant Clinical Research Coordinator Program: A Pathway for Recruitment in Radiation Oncology. Advances in Radiation Oncology, 9(7), 101504. -
Radiotherapy Plan Quality Assurance in NRG Oncology Trials for Brain and Head/Neck Cancers: An AI-Enhanced Knowledge-Based Approach
Wang, D., Geng, H., Gondi, V., Lee, N. Y., Tsien, C. I., Xia, P., … Xiao, Y. (2024). Radiotherapy Plan Quality Assurance in NRG Oncology Trials for Brain and Head/Neck Cancers: An AI-Enhanced Knowledge-Based Approach. CANCERS, 16(11). -
Tert-expressing cells contribute to salivary gland homeostasis and tissue regeneration after radiation therapy.
Guan, L., Viswanathan, V., Jiang, Y., Vijayakumar, S., Cao, H., Zhao, J., … Le, Q.-T. T. (2024). Tert-expressing cells contribute to salivary gland homeostasis and tissue regeneration after radiation therapy. Genes & Development. -
International Recommendations on Postoperative Management for Potentially Resectable Locally Recurrent Nasopharyngeal Carcinoma.
Li, J.-S. S., Blanchard, P., Wong, C. H., Ahn, Y. C., Bonomo, P., Bresson, D., … Ng, W. T. (2024). International Recommendations on Postoperative Management for Potentially Resectable Locally Recurrent Nasopharyngeal Carcinoma. International Journal of Radiation Oncology, Biology, Physics. -
Large Language Model-Augmented Auto-Delineation of Treatment Target Volume in Radiation Therapy.
Rajendran, P., Yang, Y., Niedermayr, T. R., Gensheimer, M., Beadle, B., Le, Q.-T. T., … Dai, X. (2024). Large Language Model-Augmented Auto-Delineation of Treatment Target Volume in Radiation Therapy. ArXiv. -
A case for the study of native extracellular vesicles.
Nambiar, D., Le, Q.-T., & Pucci, F. (2024). A case for the study of native extracellular vesicles. Frontiers in Oncology, 14, 1430971.
Clinical Trials
Clinical trials are research studies that evaluate a new medical approach, device, drug, or other treatment. As a Stanford Health Care patient, you may have access to the latest, advanced clinical trials.
Open trials refer to studies currently accepting participants. Closed trials are not currently enrolling, but may open in the future.
- d-Limonene +Radiation +Platinum Based Chemo for Xerostomia Prevention in Locally Advanced Head and Neck Squamous Cell Carcinoma
- Novel Serum Markers for Monitoring Response to Anti-Cancer Therapy
- Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
- Identification and Characterization of Novel Proteins and Genes in Head and Neck Cancer
- Identification of Secreted Markers for Tumor Hypoxia in Patients With Head and Neck or Lung Cancers
- Human Salivary Gland Disposition of Alda-341 in Patients Undergoing Salivary Gland Surgery
- Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
- Identification of Serum Markers For Tumor Hypoxia in Non-Small Cell Lung Cancers
- Avoiding the Hippocampus During Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
- Individualized Lung Tumor Stereotactic Ablative Radiotherapy (iSABR)
- Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer
- Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors
- Surgery With or Without Internal Radiation Therapy Compared With Stereotactic Body Radiation Therapy in Treating Patients With High-Risk Stage I Non-Small Cell Lung Cancer
Practice Locations
Radiation Oncology at Blake Wilbur Building Palo Alto, CA
Palo Alto, CARadiation Oncology at Blake Wilbur Building
875 Blake Wilbur Drive
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereCyberKnife Stereotactic Radiosurgery Program at 875 Blake Wilbur Palo Alto, CA
Palo Alto, CACyberKnife Stereotactic Radiosurgery Program at 875 Blake Wilbur
875 Blake Wilbur Drive
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereHead and Neck Cancer Program at 875 Blake Wilbur Palo Alto, CA
Palo Alto, CAHead and Neck Cancer Program at 875 Blake Wilbur
875 Blake Wilbur Drive
Palo Alto , CA 94304
Make An Appointment More Clinic Information Getting HereImportant Information about Our Organizations and Physician Affiliation
Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are each independent nonprofit organizations that are affiliated with but separate from each other and from Stanford University. The physicians who provide care at facilities operated by Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners are faculty, foundation, or community physicians who are not employees, representatives, or agents of Stanford Health Care, Stanford Health Care Tri- Valley, or Stanford Medicine Partners. Stanford Health Care, Stanford Health Care Tri-Valley, and Stanford Medicine Partners do not exercise control over the care provided by such faculty, foundation, and community physicians and are not responsible for their actions.
Patient Reviews
(115 reviews)
View More
Referring Physicians
PHYSICIAN HELPLINE
Fax: 650-320-9443
Monday–Friday, 8 a.m.–5 p.m.
Stanford Health Care provides comprehensive services to refer and track patients, as well as the latest information and news for physicians and office staff. For help with all referral needs and questions, visit Referral Information.
You may also submit a web referral or complete a referral form and fax it to 650-320-9443 or email the Referral Center at ReferralCenter@stanfordhealthcare.org.
- Send referrals online
- Place radiology and lab orders
- View referral status
- Access medical records